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The map label for this gene is rcsC [H]

Identifier: 222524154

GI number: 222524154

Start: 1101503

End: 1103302

Strand: Reverse

Name: rcsC [H]

Synonym: Chy400_0870

Alternate gene names: 222524154

Gene position: 1103302-1101503 (Counterclockwise)

Preceding gene: 222524157

Following gene: 222524150

Centisome position: 20.94

GC content: 55.0

Gene sequence:

>1800_bases
ATGTGGTATTTCACACCCTACATCCTCTTGCCACTTGCTGCGGTGCTCCTGGCGTTAGGGGCAATGCGTCTGGCCTGGCC
ATATCGGCGACTACCGGTGGCAAAGGTCTTTCTTGGCCTGATGTTTAGCACGATCTGGTGGTCGATGTGTCATGCCCTGG
AATTGTCGAATGCGACTATTGCCGGTAAGGTGCTGCTGAGCAATATTCAATACATCAGTGTGGTGAGCGTGCCATTATTG
TGGCTATTGTTTGCACTGTGTTACACAGATCGCGCTCATCTGTTGCCGCGTAGTGTGCTGTACAGTTTGATCCTGCTCCA
AAGCGGATTTTTGATCGGTGCCTGGACAAATGGCTGGCATCGGTTGATGTGGCCGCGGGTGGAATTGACCTATACTGCCG
GTGGCCTTTGGGTGCTGACCGGGCCGCATGGGCCGCTGTGGTACGCCAGTGTTCTGAGCGCCTATGCGATGGTGTTTGCC
GGTACGGTGTTGATGATCAATCAGGCGATCCGCAGTCAATCACTCTACCGCGCCCAGGCGATCAGTCTGGTGGTTGGAGC
ACTCCTCCCTTGGGCAGCGAGTATGCTCTTCGTAACCGGACTCAGTCCGATCCCCTTTGTTGACCCAACGCCGGTCGCTT
TCGCGCTCGGTGGGCTGGCTTTCACCGTTGCGATGCAGCGCTACCGCGCACTTGACCTCTTGCCGGCGGCGCGTGAGCGA
ATCGTTGATCAGATGCCTGATGCGATTATCGTGCTTGATATGCATGATCGGATCATTGACCTGAATCCGGCAGCACAGGC
GATTTTGTCGGCAACGACAGATGTTCTTGGTAAGTCGTTGGCACGTGTTGCACCGCCCTGGCTGATTGAGCAGGTCCGTG
ATCGGTACGAAGGCCAGTTTGAGGTGCAACAGACCGGTGAAACGGGGACGACGACCTACGATTTACGTTGTACCACGTTG
CGCGATCGCGATGGCAGTCCGGCGGGGCGGATCTTTGTGCTGCGCGACATTACCCTCTTCAAGCAGGCAGCACAGGCTTT
GCAAGAAGCGAAGGAGGCGGCTGAAGCGGCCAGTCAAGCGAAAAGTGCCTTCCTATCAATGATGAGTCACGAATTGCGGA
CACCACTGACGGCTATTTTGGGCTACAGTGAGTTTCTACGCGAGGATTTGTTGAATCGGGATCTGCATTCACTGACATCC
GACCTTGACCGGATCATTACGGCTGGACGGCATTTGTTGACGCTGATTAACGATATTCTTGATTACGCGCGCCTGGAAGC
GAATGCCGTGACGATTCACCCAGAGCCAGTTCACATGTCTACGCTGATCAATGAGGTTGTGATGACGTTGCAGGGACTGG
CGAAGCAGGGGCAAAATACTATCACCGTTACTGTGGAACCAGACCTGCCACCGGTGTTGGCCGATCCGGTACGTTTACGT
CAGGTGTTGTTGAACCTGGTTGGCAATGCCTGTAAGTTTACCGGGCAGGGTGAGATTCGTGTTCACTGCTACCGTTCAAC
CACTGCTGAGATTCAGATTGATGTGAGCGATACGGGGATCGGTATTGCTGCCGATCAGCTTCAGCACCTGTTCAAGCCAT
TTGTGCAGGTAGATAATGGTCCAACCAGACGCTACGGTGGCACCGGGCTGGGACTGGCTATCTGTCAGCGCTTGTGTCAG
GTGATGGGAGGCGCGATCCTGGTCACGAGTGAACCGGGCCGTGGTTCGACCTTTAGTGTGCGTTTGCCGATCACAGGTGT
GCCATCTGCACCATGTGAAGTTTCACAAGAGGATGGCTAA

Upstream 100 bases:

>100_bases
TCTATTATACAGGGTTTCTGATTGGTTGGCAAGTCATGGTATGCTATGCTGTATATTGCGTTTATGATCGCGAATAATCG
CAGCGATAACACCTGTGCTT

Downstream 100 bases:

>100_bases
GGATGTGTCGCTGACACAGATGCGCTCCGGTGTGATGGGTAATCTATTGAGGATGAATTCAGTAGTCACACTTGGGGTGC
GGAAGCCTGGCTTCCGCACC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MWYFTPYILLPLAAVLLALGAMRLAWPYRRLPVAKVFLGLMFSTIWWSMCHALELSNATIAGKVLLSNIQYISVVSVPLL
WLLFALCYTDRAHLLPRSVLYSLILLQSGFLIGAWTNGWHRLMWPRVELTYTAGGLWVLTGPHGPLWYASVLSAYAMVFA
GTVLMINQAIRSQSLYRAQAISLVVGALLPWAASMLFVTGLSPIPFVDPTPVAFALGGLAFTVAMQRYRALDLLPAARER
IVDQMPDAIIVLDMHDRIIDLNPAAQAILSATTDVLGKSLARVAPPWLIEQVRDRYEGQFEVQQTGETGTTTYDLRCTTL
RDRDGSPAGRIFVLRDITLFKQAAQALQEAKEAAEAASQAKSAFLSMMSHELRTPLTAILGYSEFLREDLLNRDLHSLTS
DLDRIITAGRHLLTLINDILDYARLEANAVTIHPEPVHMSTLINEVVMTLQGLAKQGQNTITVTVEPDLPPVLADPVRLR
QVLLNLVGNACKFTGQGEIRVHCYRSTTAEIQIDVSDTGIGIAADQLQHLFKPFVQVDNGPTRRYGGTGLGLAICQRLCQ
VMGGAILVTSEPGRGSTFSVRLPITGVPSAPCEVSQEDG

Sequences:

>Translated_599_residues
MWYFTPYILLPLAAVLLALGAMRLAWPYRRLPVAKVFLGLMFSTIWWSMCHALELSNATIAGKVLLSNIQYISVVSVPLL
WLLFALCYTDRAHLLPRSVLYSLILLQSGFLIGAWTNGWHRLMWPRVELTYTAGGLWVLTGPHGPLWYASVLSAYAMVFA
GTVLMINQAIRSQSLYRAQAISLVVGALLPWAASMLFVTGLSPIPFVDPTPVAFALGGLAFTVAMQRYRALDLLPAARER
IVDQMPDAIIVLDMHDRIIDLNPAAQAILSATTDVLGKSLARVAPPWLIEQVRDRYEGQFEVQQTGETGTTTYDLRCTTL
RDRDGSPAGRIFVLRDITLFKQAAQALQEAKEAAEAASQAKSAFLSMMSHELRTPLTAILGYSEFLREDLLNRDLHSLTS
DLDRIITAGRHLLTLINDILDYARLEANAVTIHPEPVHMSTLINEVVMTLQGLAKQGQNTITVTVEPDLPPVLADPVRLR
QVLLNLVGNACKFTGQGEIRVHCYRSTTAEIQIDVSDTGIGIAADQLQHLFKPFVQVDNGPTRRYGGTGLGLAICQRLCQ
VMGGAILVTSEPGRGSTFSVRLPITGVPSAPCEVSQEDG
>Mature_599_residues
MWYFTPYILLPLAAVLLALGAMRLAWPYRRLPVAKVFLGLMFSTIWWSMCHALELSNATIAGKVLLSNIQYISVVSVPLL
WLLFALCYTDRAHLLPRSVLYSLILLQSGFLIGAWTNGWHRLMWPRVELTYTAGGLWVLTGPHGPLWYASVLSAYAMVFA
GTVLMINQAIRSQSLYRAQAISLVVGALLPWAASMLFVTGLSPIPFVDPTPVAFALGGLAFTVAMQRYRALDLLPAARER
IVDQMPDAIIVLDMHDRIIDLNPAAQAILSATTDVLGKSLARVAPPWLIEQVRDRYEGQFEVQQTGETGTTTYDLRCTTL
RDRDGSPAGRIFVLRDITLFKQAAQALQEAKEAAEAASQAKSAFLSMMSHELRTPLTAILGYSEFLREDLLNRDLHSLTS
DLDRIITAGRHLLTLINDILDYARLEANAVTIHPEPVHMSTLINEVVMTLQGLAKQGQNTITVTVEPDLPPVLADPVRLR
QVLLNLVGNACKFTGQGEIRVHCYRSTTAEIQIDVSDTGIGIAADQLQHLFKPFVQVDNGPTRRYGGTGLGLAICQRLCQ
VMGGAILVTSEPGRGSTFSVRLPITGVPSAPCEVSQEDG

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=41.7624521072797, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=40, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI87081816, Length=249, Percent_Identity=42.1686746987952, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI48994928, Length=290, Percent_Identity=35.5172413793103, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI1788713, Length=380, Percent_Identity=28.4210526315789, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1788549, Length=365, Percent_Identity=27.1232876712329, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=33.6322869955157, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=31.2, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=30.1310043668122, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=29.3877551020408, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=31.4655172413793, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788393, Length=241, Percent_Identity=25.7261410788382, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=247, Percent_Identity=27.5303643724696, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=28.5140562248996, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789808, Length=254, Percent_Identity=27.9527559055118, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790300, Length=363, Percent_Identity=27.8236914600551, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790861, Length=245, Percent_Identity=28.1632653061224, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788279, Length=227, Percent_Identity=25.1101321585903, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790567, Length=369, Percent_Identity=25.7452574525745, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790551, Length=227, Percent_Identity=29.0748898678414, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=75, Percent_Identity=46.6666666666667, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65769; Mature: 65769

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWYFTPYILLPLAAVLLALGAMRLAWPYRRLPVAKVFLGLMFSTIWWSMCHALELSNATI
CCEEHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AGKVLLSNIQYISVVSVPLLWLLFALCYTDRAHLLPRSVLYSLILLQSGFLIGAWTNGWH
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCH
RLMWPRVELTYTAGGLWVLTGPHGPLWYASVLSAYAMVFAGTVLMINQAIRSQSLYRAQA
HHCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISLVVGALLPWAASMLFVTGLSPIPFVDPTPVAFALGGLAFTVAMQRYRALDLLPAARER
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVDQMPDAIIVLDMHDRIIDLNPAAQAILSATTDVLGKSLARVAPPWLIEQVRDRYEGQF
HHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEE
EVQQTGETGTTTYDLRCTTLRDRDGSPAGRIFVLRDITLFKQAAQALQEAKEAAEAASQA
EEEECCCCCCEEEEEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
KSAFLSMMSHELRTPLTAILGYSEFLREDLLNRDLHSLTSDLDRIITAGRHLLTLINDIL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYARLEANAVTIHPEPVHMSTLINEVVMTLQGLAKQGQNTITVTVEPDLPPVLADPVRLR
HHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
QVLLNLVGNACKFTGQGEIRVHCYRSTTAEIQIDVSDTGIGIAADQLQHLFKPFVQVDNG
HHHHHHHCCHHEECCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
PTRRYGGTGLGLAICQRLCQVMGGAILVTSEPGRGSTFSVRLPITGVPSAPCEVSQEDG
CCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MWYFTPYILLPLAAVLLALGAMRLAWPYRRLPVAKVFLGLMFSTIWWSMCHALELSNATI
CCEEHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AGKVLLSNIQYISVVSVPLLWLLFALCYTDRAHLLPRSVLYSLILLQSGFLIGAWTNGWH
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCH
RLMWPRVELTYTAGGLWVLTGPHGPLWYASVLSAYAMVFAGTVLMINQAIRSQSLYRAQA
HHCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISLVVGALLPWAASMLFVTGLSPIPFVDPTPVAFALGGLAFTVAMQRYRALDLLPAARER
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVDQMPDAIIVLDMHDRIIDLNPAAQAILSATTDVLGKSLARVAPPWLIEQVRDRYEGQF
HHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEE
EVQQTGETGTTTYDLRCTTLRDRDGSPAGRIFVLRDITLFKQAAQALQEAKEAAEAASQA
EEEECCCCCCEEEEEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
KSAFLSMMSHELRTPLTAILGYSEFLREDLLNRDLHSLTSDLDRIITAGRHLLTLINDIL
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYARLEANAVTIHPEPVHMSTLINEVVMTLQGLAKQGQNTITVTVEPDLPPVLADPVRLR
HHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
QVLLNLVGNACKFTGQGEIRVHCYRSTTAEIQIDVSDTGIGIAADQLQHLFKPFVQVDNG
HHHHHHHCCHHEECCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
PTRRYGGTGLGLAICQRLCQVMGGAILVTSEPGRGSTFSVRLPITGVPSAPCEVSQEDG
CCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]