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The map label for this gene is spoVD [H]

Identifier: 222524109

GI number: 222524109

Start: 1038279

End: 1040096

Strand: Reverse

Name: spoVD [H]

Synonym: Chy400_0825

Alternate gene names: 222524109

Gene position: 1040096-1038279 (Counterclockwise)

Preceding gene: 222524110

Following gene: 222524108

Centisome position: 19.74

GC content: 58.03

Gene sequence:

>1818_bases
ATGGCTACTACGACCCGCCGCTCATCTGTGCCAACGCCAACGACGGCAGCAACGACGCCGGTTCCCGCAGGCAAGCCACT
ACCGCGCTGGCGCTTGCAGGTGCTCCTGGCAAGTTGTTTTCTGATAACAATTATCATCGCTGTTCGCCTCGTTGATCTCC
AGGTGGTGCGTAGCAACGACCTCGCTCGTAAGGCGCGGCTGGAAATTGAGACGCCGACCTTGCTGGCACCGCGCCGTGGG
CAGATTAGCGATGCCAGTGGGACAGTGCTGGCAATGGATGTCGAACGCCAGAGTCTGTTTGCTGTGCCGCCCCAGGTGCC
TGCTGCCCGCAAGGCGGAGATTGCAGTGTTGATTGCCGGCCTGACTGATCAGCCGGCAGATCAGATTTTATCGGCGTTAC
GTTCGGATCGGCAGTGGGTGCGTCTGGCGCGCTGGCTTGAACCAGAAGTGGCGGCACAGGTCGCCGAACTGGAGTTGCCC
GGTCTCTGGCTGGTCTACGAGCCGATGCGTTTCTATCCGCAGGGTATCTCTGCGGCTCAGATTGTCGGTGCATTAAACCT
GAATGGCGAAGGCGTCAGCGGGATCGAAGCCTACTACGATCAATTACTACGTGGTACCGAAGGGCGGATTGAAGGTGAGT
TTGATCCGAATCGCAACCCGATTGCAACCAGCCTGGCCCGCACGCTGCCACCGCAAGATGGTGCCGATTTGCAGTTGACC
ATCGATCCATTTATTCAGCAGGTGGCGGAACGAGAGCTACAGCAGGCCATCGATGAGCAGAATGCCGATGGCGGTACGAT
TATCGTGCTTGATCCGCGTAGTGGCGCTATTCTGGCAATGGCCAACTGGCCATTCTTCGATCCGAATCGCTGGCAAGAGT
ATCCACCAGAGGTGTATGGACGTAACCCGGCAATCGGTACGATTTACGAACCGGGCAGTACCTTTAAGATGGTGACGGCA
GCGGCGGCCCTCAGTTCAGGGGTGGTGACGACAACGACGACGGTTGATGATCCGGGTTGGGTGATACGCTACGGTCAGAC
GTTACGCAATTTTGATGCGGCACCCCACGGCCCGCTGACGCTGGCCGGGATGATTTACTATTCGAGCAATGTGGCGGCAT
TGCAATTTAATGAGTTGGTTGGGCCAGAGACCTTTTACCGGGTCTTGACGCGCTTCGGTTTTGGCCAGCCGACCGGCGTC
GATCTGGCCGGTGAAGAGAGCGGGATTGTTAATTTTTATGGTAGTGCCGGCTACAGTCCGCTCACCTTTTTGACCAACGC
CTACGGTCAGGGGATTTCAGTAACCCCGTTGCAGTTGGTACAGGCCGCCGGTGCCATCGCGAATGATGGGGTGATGATGC
GGCCTTATGTGGTGCAGCAGATTTGCCGCAACAATGAATGTGTCCGCACGGAGCCACAAGTCGTTGCCCGACCGGTGACC
CCAGACGTGGCTCGTGCAGTGCGCGAGATGATGGTCGAGTCGGCGAATCACTACGCACCGGTGATTTGGGGGCCGCGCAC
CGGTAACTGGAGTGACCAGTGGCTTGTACCCGGTTATCGGGTGGGAGCCAAAACGGGAACGGCCTCGATCCCGTTGCCCG
GCGGGGGGTACGATCCCGTCTACACGATTGGCTCGGTGTTGGGCATTGCCCCGGTCGATGAACCGCGGTTTGTCGTACTG
GTGAAGATTGATCGACCAAAGAAGGATACGCTCGGCGTACTTACTGCTATTCCGGTCTATTACAACGTGGTCGAGCAGTT
GTTACGCTACGCGCATATACCGCCTGATCGTAGCCTGGTTAGTCCAGGGCAACCGTGA

Upstream 100 bases:

>100_bases
CATGAAACGGGCCACCGAATTGGGCTTTCGCACACCGACACCCGATCAGGTGCGGTATGTTCGTATTCCAGATTTACCGC
CACTTGATGAGTAACCTGCT

Downstream 100 bases:

>100_bases
TGGGGCAGGAAGATGTTCATCTGGCGGGTTTCAGCTTGTTATCAGCTTGTGCCGACCTCTACCGATAGAGGTCGGCGAAA
GGGAGATGCTATAATGGCCT

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 605; Mature: 604

Protein sequence:

>605_residues
MATTTRRSSVPTPTTAATTPVPAGKPLPRWRLQVLLASCFLITIIIAVRLVDLQVVRSNDLARKARLEIETPTLLAPRRG
QISDASGTVLAMDVERQSLFAVPPQVPAARKAEIAVLIAGLTDQPADQILSALRSDRQWVRLARWLEPEVAAQVAELELP
GLWLVYEPMRFYPQGISAAQIVGALNLNGEGVSGIEAYYDQLLRGTEGRIEGEFDPNRNPIATSLARTLPPQDGADLQLT
IDPFIQQVAERELQQAIDEQNADGGTIIVLDPRSGAILAMANWPFFDPNRWQEYPPEVYGRNPAIGTIYEPGSTFKMVTA
AAALSSGVVTTTTTVDDPGWVIRYGQTLRNFDAAPHGPLTLAGMIYYSSNVAALQFNELVGPETFYRVLTRFGFGQPTGV
DLAGEESGIVNFYGSAGYSPLTFLTNAYGQGISVTPLQLVQAAGAIANDGVMMRPYVVQQICRNNECVRTEPQVVARPVT
PDVARAVREMMVESANHYAPVIWGPRTGNWSDQWLVPGYRVGAKTGTASIPLPGGGYDPVYTIGSVLGIAPVDEPRFVVL
VKIDRPKKDTLGVLTAIPVYYNVVEQLLRYAHIPPDRSLVSPGQP

Sequences:

>Translated_605_residues
MATTTRRSSVPTPTTAATTPVPAGKPLPRWRLQVLLASCFLITIIIAVRLVDLQVVRSNDLARKARLEIETPTLLAPRRG
QISDASGTVLAMDVERQSLFAVPPQVPAARKAEIAVLIAGLTDQPADQILSALRSDRQWVRLARWLEPEVAAQVAELELP
GLWLVYEPMRFYPQGISAAQIVGALNLNGEGVSGIEAYYDQLLRGTEGRIEGEFDPNRNPIATSLARTLPPQDGADLQLT
IDPFIQQVAERELQQAIDEQNADGGTIIVLDPRSGAILAMANWPFFDPNRWQEYPPEVYGRNPAIGTIYEPGSTFKMVTA
AAALSSGVVTTTTTVDDPGWVIRYGQTLRNFDAAPHGPLTLAGMIYYSSNVAALQFNELVGPETFYRVLTRFGFGQPTGV
DLAGEESGIVNFYGSAGYSPLTFLTNAYGQGISVTPLQLVQAAGAIANDGVMMRPYVVQQICRNNECVRTEPQVVARPVT
PDVARAVREMMVESANHYAPVIWGPRTGNWSDQWLVPGYRVGAKTGTASIPLPGGGYDPVYTIGSVLGIAPVDEPRFVVL
VKIDRPKKDTLGVLTAIPVYYNVVEQLLRYAHIPPDRSLVSPGQP
>Mature_604_residues
ATTTRRSSVPTPTTAATTPVPAGKPLPRWRLQVLLASCFLITIIIAVRLVDLQVVRSNDLARKARLEIETPTLLAPRRGQ
ISDASGTVLAMDVERQSLFAVPPQVPAARKAEIAVLIAGLTDQPADQILSALRSDRQWVRLARWLEPEVAAQVAELELPG
LWLVYEPMRFYPQGISAAQIVGALNLNGEGVSGIEAYYDQLLRGTEGRIEGEFDPNRNPIATSLARTLPPQDGADLQLTI
DPFIQQVAERELQQAIDEQNADGGTIIVLDPRSGAILAMANWPFFDPNRWQEYPPEVYGRNPAIGTIYEPGSTFKMVTAA
AALSSGVVTTTTTVDDPGWVIRYGQTLRNFDAAPHGPLTLAGMIYYSSNVAALQFNELVGPETFYRVLTRFGFGQPTGVD
LAGEESGIVNFYGSAGYSPLTFLTNAYGQGISVTPLQLVQAAGAIANDGVMMRPYVVQQICRNNECVRTEPQVVARPVTP
DVARAVREMMVESANHYAPVIWGPRTGNWSDQWLVPGYRVGAKTGTASIPLPGGGYDPVYTIGSVLGIAPVDEPRFVVLV
KIDRPKKDTLGVLTAIPVYYNVVEQLLRYAHIPPDRSLVSPGQP

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=574, Percent_Identity=29.0940766550523, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1786854, Length=491, Percent_Identity=27.2912423625255, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65706; Mature: 65575

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTRRSSVPTPTTAATTPVPAGKPLPRWRLQVLLASCFLITIIIAVRLVDLQVVRSND
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
LARKARLEIETPTLLAPRRGQISDASGTVLAMDVERQSLFAVPPQVPAARKAEIAVLIAG
CHHHHEEEECCCCEECCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCEEEEEEEC
LTDQPADQILSALRSDRQWVRLARWLEPEVAAQVAELELPGLWLVYEPMRFYPQGISAAQ
CCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCHHHCCCCCCHHH
IVGALNLNGEGVSGIEAYYDQLLRGTEGRIEGEFDPNRNPIATSLARTLPPQDGADLQLT
HEEEEECCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCEEEEE
IDPFIQQVAERELQQAIDEQNADGGTIIVLDPRSGAILAMANWPFFDPNRWQEYPPEVYG
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHCC
RNPAIGTIYEPGSTFKMVTAAAALSSGVVTTTTTVDDPGWVIRYGQTLRNFDAAPHGPLT
CCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECHHHHHCCCCCCCCEE
LAGMIYYSSNVAALQFNELVGPETFYRVLTRFGFGQPTGVDLAGEESGIVNFYGSAGYSP
EEEEEEECCCEEEEEHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCH
LTFLTNAYGQGISVTPLQLVQAAGAIANDGVMMRPYVVQQICRNNECVRTEPQVVARPVT
HHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCCCCCCCHHEEECCC
PDVARAVREMMVESANHYAPVIWGPRTGNWSDQWLVPGYRVGAKTGTASIPLPGGGYDPV
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEECCCEEECCCCCCCCCCCCCCCCCHH
YTIGSVLGIAPVDEPRFVVLVKIDRPKKDTLGVLTAIPVYYNVVEQLLRYAHIPPDRSLV
HHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SPGQP
CCCCC
>Mature Secondary Structure 
ATTTRRSSVPTPTTAATTPVPAGKPLPRWRLQVLLASCFLITIIIAVRLVDLQVVRSND
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
LARKARLEIETPTLLAPRRGQISDASGTVLAMDVERQSLFAVPPQVPAARKAEIAVLIAG
CHHHHEEEECCCCEECCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCEEEEEEEC
LTDQPADQILSALRSDRQWVRLARWLEPEVAAQVAELELPGLWLVYEPMRFYPQGISAAQ
CCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCHHHCCCCCCHHH
IVGALNLNGEGVSGIEAYYDQLLRGTEGRIEGEFDPNRNPIATSLARTLPPQDGADLQLT
HEEEEECCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCEEEEE
IDPFIQQVAERELQQAIDEQNADGGTIIVLDPRSGAILAMANWPFFDPNRWQEYPPEVYG
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHCC
RNPAIGTIYEPGSTFKMVTAAAALSSGVVTTTTTVDDPGWVIRYGQTLRNFDAAPHGPLT
CCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECHHHHHCCCCCCCCEE
LAGMIYYSSNVAALQFNELVGPETFYRVLTRFGFGQPTGVDLAGEESGIVNFYGSAGYSP
EEEEEEECCCEEEEEHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCH
LTFLTNAYGQGISVTPLQLVQAAGAIANDGVMMRPYVVQQICRNNECVRTEPQVVARPVT
HHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCCCCCCCHHEEECCC
PDVARAVREMMVESANHYAPVIWGPRTGNWSDQWLVPGYRVGAKTGTASIPLPGGGYDPV
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEECCCEEECCCCCCCCCCCCCCCCCHH
YTIGSVLGIAPVDEPRFVVLVKIDRPKKDTLGVLTAIPVYYNVVEQLLRYAHIPPDRSLV
HHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SPGQP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]