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The map label for this gene is bpr [H]

Identifier: 222523988

GI number: 222523988

Start: 878463

End: 882683

Strand: Reverse

Name: bpr [H]

Synonym: Chy400_0703

Alternate gene names: 222523988

Gene position: 882683-878463 (Counterclockwise)

Preceding gene: 222523989

Following gene: 222523987

Centisome position: 16.75

GC content: 57.17

Gene sequence:

>4221_bases
ATGCGTCGTCTTCTGTTGCTCTGCACGTTGATCGCGATACTGGGTAGTGTTTTACCGGTGGCAGTACCGCGAGTGGCCGC
TACCCAAACGATTGGATGGCATTCTGATGTGCCGGTGGCGCGTCAGCACCACGCAATGGCGGCGAATGCCACAGAGATAT
TTCTGTTTGGTGGCACAGTTGTCGACCAGAATCCACAATTACAGAATGACTTATGGGTATGGCGTGAGGGGCGCTGGCAA
TGGTTAGGCTTCGGTGGACCTGGACCGCGTAGTCATACAGCGCTGGCGTATGATGCACGTCGTCAGGAACTGGTGCTCTT
TGGTGGGTGGGACGGCCAAACGATGCTGGGTGATACGTGGGTATGGTCAGCCGGGGGATGGCAGCAACGCCAGCCCGCCC
GATCTCCATCACCACGTCGTGCTCACGCCATGGTCTACGATCCTCAGCGCGAGCAGATCCTGCTCTTCGGCGGTTATGAT
GGCCGTTCACGGAATGATACCTGGGTCTGGGATGGCGTTACCTGGACACAACTCTTCCCGGACAGTGAGCCATCAACGCG
GCACGAACACGCCATGGCCTATGATGCAGCTTCCCGACAGATCGTGCTGTTTGGTGGTGCGTCGGTCACCGATTTCGGTT
CGCAGATACTTGATGATACATGGGTGTGGGATGGTACAAGCTGGGTTTTTCAGTCACCAACAACATCACCTTCTGCCCGT
ACTGATCACATCCTGGTGACAACAACAGCGGGTGTTTTACTGTTTGGCGGCGAAGATGAGCAAACCCTGCTTGACGACAC
CTGGTTGTGGCACAACCATTCCTGGCAACGCTTAACACCTTCTCTGTCACCTTTGGCGCGTAGTGGTGCAGCAGCAGCGT
TTGCTCCTGTGCAGCAGCGTCTGCTCTTGTTTGGCGGGAATGGGCTTTTTGAAACATACGCCGATACCTGGTTCTGGAAT
GGGAGTACCTGGCAGCCGCTTTCCGGGCCGTCAGCTCCTTCCTCGCGAACACAGACGGCGCTGGCTGATGATGTTGGACG
CGGAACCATTGTTTTGTTCGGTGGTATTGACGGTGAACCGCTAGACGATACCTGGTTATGGACTGCCGAACAGGGCTGGC
GAATGGTATCACCGCCAACACGACCTTCCCCTCGTTTCGGCCACGCAATGGCCTATGATCCACTTCGTCAAGAGGTTGTC
CTCTTTGGGGGGTACAGTGGTAGTAGCCGTAACGATACCTGGGTGTGGAATGGTAGCACGTGGGTACTGCGCACGCCGTC
TGTGTCACCACCACCACGCTGGGGACACACCCTGACGTATGATGCCGCTCGTGGTCGGATCGTCCTGTTCGGTGGCGCTC
AAGGCACAGCCGGCTTTTACAGTGATACCTGGGAATGGGATGGCCAGACCTGGATTGCGCTATCACCCACTGTTCGTCCG
CCGGCACGCCGCAACCATGCTGCTGCCTATGATTCACTCCGTGGTCGGGTAGTACTGTTTGGTGGTTATGCGCTGCAGGG
CGAAACACCAACCTACTTCGATGATACGTGGGAATGGGATGGGAGTCGCTGGCAGCAGGTGGTGGCTCGTGGCCCTGCTG
CACGTATGGGACACACCCTCTTCTACGATGCCGTTCGCCAAAAGAGCATCCTTTTCGGTGGGATTGGTGATGACGAACTG
AGTGAAGTGCTCTGGGCCTGGGATGGAGTGTCCTGGACGCAACTCCCTGATGTACCGCGTCCTCCTGTATTGTCATTCCA
CGCGGCTGCGTATCAACTGGCAACCTGCCGGGCCTTGATTGTTGGTGGCATACCAGAACGTGAACAACTTTACGTATGGC
AACGTGCTGAGTCCTCTTGCTCGGCTTTGCCGACGGCTCGAATTGACAGTGTGTCACCGAATCCTGCTAATCGCAGTACT
GATCGTATTCAGTTGATCGGGAGTGGTTTTGCCGCTAACGGGAGTGGTCGCCAGATTAATGCCTATCGCTGGTTGATCAA
TGGTGCTGTCCTGCCTGGCACAACCGCTCACCAGACGCTCAATGCGGCTGATTTCGCGGTCGGTGTCTACGAAGTCGCGC
TGGCGGTGCGTGACAGTGCCGGCATCTGGTCGGCACCTGTTACTCAAACCTTAACGATTATCGATAATCCGCAGATTGTA
GTGGCAACCGATCCAATTTCAGCAACCGTCGTGAGCGGTGAGCGTACTGAGCGATTGTTGCCGATAAGCAATCGTGGTGC
CAGCCCGTTGACGATTAATTTGCGGGTTGAGGCTGGTACTGCAACCGCTTCGTCCCATCCGACTGCTGCAACGGATACCT
CATGGACGTTGCCCCGTCTCTATCGTCCACCCGACCGTCTCGATGCTCGCCTTGCCCACTTTGCTCAAACAACATCAACG
CGCCATGAGACCTATCTGGTCTACATGGATGAAGTGGCCGATCTGCGGGCAGCAATGCAAATTGAAGACTGGCGTGAACG
GGGGCGTGCCATAGTCCGTCATCTTCAGGAAGTTGCCGCACGTAGCCAGGCCGAGACGTTACGCTATCTGGAAGGGCAGC
GTCGAACCGGCGCAGTGAGTTTTTACTGGTCGCTGTACAGCGTAAATGCGATTGTGGTGCGAGGGGATGCCGAAACTCTG
CGCACATTGCTGGCGCAGCCACGTGTTATTGGGATTACGATCAGCGAGACCTATGCGATTGATGAGATGCCAACTGGCGC
CTCCCCGCAATCAACTGGCGTCAGATGGAACATTAGACGGATTGGGGCTGATCGGGTCTGGAATGAACTCGGTGTGCGCG
GCGAAGGTGTGGTTGTCGGGAGTATTGACACCGGGGCGAAGCTCGATCATCCGCTTCTCAACGCCAATTATCGTGGTCGT
TATCCCGATGGTAGTTACGATCACAGCTATAGCTGGTTTGATCCGACCGGTACTTTTCCCGACGCGCCCGGTGACGATAA
CGGACATGGCACGCATACGATTGGCACGATGGTCGGTATTGACGGTATCGGTGTCGCACCGGGTGCCCGATGGATCGCCG
CTCGTGCCTGTAGTCGTCGCGCGTGTCAGGATATTGATATCTTGCGGGCGATGGAGTGGATGCTTGCGCCGTATCCGTCT
ACACTCGGCCCGGTGGCAGCTAATCCTGACATGCGACCCCAGGTGGTGAATAATTCGTGGGGCGGGCCGGGTGGTCGGCC
ACTGTTCCAGCAGATGGTAGCCGTATGGCGCGCCGCAGGTATCTTTCCTGCGTTTGCTGCCGGGAATTGCGGGCAGGCCC
GTCCAGGCTGCCTTGTTACCGGTGTGGGTAGTGTCAGTTCGCCCGGTGATTATGCCGAGAGTTTTGCTACCGGTGCCACG
CATGATAACGATACACTGGCAGCCTTCAGTAGCCAGGGCCCGTCGCGTTTGACCAGTAATGTGAAGCCGGATCTCGTTGC
GCCTGGGGTGGCCATCGAGTCGGCGGCACTGAATGGTGGCACGCTTCCCCAGAACGGTACCTCGATGGCCAGTCCTCACA
CCGCAGGAGCAGTGGCGCTCCTGCTATCGCTTCGCCCCGGTCTGGCTATTGACCAGCTTGAAGCCTTACTCCGCACAACC
GCCCGTGATCTGGCAGCACCGGGGCCTGATCAACAGACCGGCTATGGCCTGCTCGATGTCTACGCGGCAGCTCAGGCAGC
TCGCACCGGTCTGGGCTGGTTGCGACTGCCACAAACCAGTGGCGTGATTCAGCCTGGTCAAACCCTCTCCATTCCCATTC
ACTTTGATGGTCGTGGCATGCCGGCGGGCACATATCGGGCTGTGCTCATTATTCAAAGTAATGATCCATCGGCTGCCGAA
ATTCGCATTCCGGTGAGTCTCATTGTACAGAGAGTACTTCGGCAATCGCATCCATTGATTACTCACCGTACCGCTGATGG
CATGCTGATCCGCTGGACAGCGCCTGATGGTCGGATTGCCCGCCTGGAGTACGCCGTGCAGGAAGGAGGGCCGTGGATCA
GGCAAGTCGGTACCGCGAGTGCCATTCCAGGAGAGACACTCTTCGTACTCCGTGGCTTACAGCCAGACACTACCTACTTC
CTGCGTCTGATTGCGATGGATGGCAGCATTGAAGATAACGGAGGTCGTTTCTATCGGGTTACCACAGCACCTGCACTCCC
CTTTGCCATTGACGACATCGTCACGCCGGTTCGGATCTATGTGCCGCTGATTCAGCGCTAA

Upstream 100 bases:

>100_bases
ATACTCTCCCCTCCATACCCTGATCATTGCCAAAAACCACCTTTTCCCTCCGTCTCTTTCTCATAGTAAACCCTAATCTA
TCCAGGTTTGGGAGTGAACT

Downstream 100 bases:

>100_bases
GTTGGGGAAAGGATGGTTCTATGCGTACACGCTCTCTCCGTCCATGGTGGCTATCGTTTGGGTTGATTGCACTGCTCCTG
CTCAGTGTAGTGCGGCCAAT

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: 90 kDa serine proteinase; Esterase; RP-I protease [H]

Number of amino acids: Translated: 1406; Mature: 1406

Protein sequence:

>1406_residues
MRRLLLLCTLIAILGSVLPVAVPRVAATQTIGWHSDVPVARQHHAMAANATEIFLFGGTVVDQNPQLQNDLWVWREGRWQ
WLGFGGPGPRSHTALAYDARRQELVLFGGWDGQTMLGDTWVWSAGGWQQRQPARSPSPRRAHAMVYDPQREQILLFGGYD
GRSRNDTWVWDGVTWTQLFPDSEPSTRHEHAMAYDAASRQIVLFGGASVTDFGSQILDDTWVWDGTSWVFQSPTTSPSAR
TDHILVTTTAGVLLFGGEDEQTLLDDTWLWHNHSWQRLTPSLSPLARSGAAAAFAPVQQRLLLFGGNGLFETYADTWFWN
GSTWQPLSGPSAPSSRTQTALADDVGRGTIVLFGGIDGEPLDDTWLWTAEQGWRMVSPPTRPSPRFGHAMAYDPLRQEVV
LFGGYSGSSRNDTWVWNGSTWVLRTPSVSPPPRWGHTLTYDAARGRIVLFGGAQGTAGFYSDTWEWDGQTWIALSPTVRP
PARRNHAAAYDSLRGRVVLFGGYALQGETPTYFDDTWEWDGSRWQQVVARGPAARMGHTLFYDAVRQKSILFGGIGDDEL
SEVLWAWDGVSWTQLPDVPRPPVLSFHAAAYQLATCRALIVGGIPEREQLYVWQRAESSCSALPTARIDSVSPNPANRST
DRIQLIGSGFAANGSGRQINAYRWLINGAVLPGTTAHQTLNAADFAVGVYEVALAVRDSAGIWSAPVTQTLTIIDNPQIV
VATDPISATVVSGERTERLLPISNRGASPLTINLRVEAGTATASSHPTAATDTSWTLPRLYRPPDRLDARLAHFAQTTST
RHETYLVYMDEVADLRAAMQIEDWRERGRAIVRHLQEVAARSQAETLRYLEGQRRTGAVSFYWSLYSVNAIVVRGDAETL
RTLLAQPRVIGITISETYAIDEMPTGASPQSTGVRWNIRRIGADRVWNELGVRGEGVVVGSIDTGAKLDHPLLNANYRGR
YPDGSYDHSYSWFDPTGTFPDAPGDDNGHGTHTIGTMVGIDGIGVAPGARWIAARACSRRACQDIDILRAMEWMLAPYPS
TLGPVAANPDMRPQVVNNSWGGPGGRPLFQQMVAVWRAAGIFPAFAAGNCGQARPGCLVTGVGSVSSPGDYAESFATGAT
HDNDTLAAFSSQGPSRLTSNVKPDLVAPGVAIESAALNGGTLPQNGTSMASPHTAGAVALLLSLRPGLAIDQLEALLRTT
ARDLAAPGPDQQTGYGLLDVYAAAQAARTGLGWLRLPQTSGVIQPGQTLSIPIHFDGRGMPAGTYRAVLIIQSNDPSAAE
IRIPVSLIVQRVLRQSHPLITHRTADGMLIRWTAPDGRIARLEYAVQEGGPWIRQVGTASAIPGETLFVLRGLQPDTTYF
LRLIAMDGSIEDNGGRFYRVTTAPALPFAIDDIVTPVRIYVPLIQR

Sequences:

>Translated_1406_residues
MRRLLLLCTLIAILGSVLPVAVPRVAATQTIGWHSDVPVARQHHAMAANATEIFLFGGTVVDQNPQLQNDLWVWREGRWQ
WLGFGGPGPRSHTALAYDARRQELVLFGGWDGQTMLGDTWVWSAGGWQQRQPARSPSPRRAHAMVYDPQREQILLFGGYD
GRSRNDTWVWDGVTWTQLFPDSEPSTRHEHAMAYDAASRQIVLFGGASVTDFGSQILDDTWVWDGTSWVFQSPTTSPSAR
TDHILVTTTAGVLLFGGEDEQTLLDDTWLWHNHSWQRLTPSLSPLARSGAAAAFAPVQQRLLLFGGNGLFETYADTWFWN
GSTWQPLSGPSAPSSRTQTALADDVGRGTIVLFGGIDGEPLDDTWLWTAEQGWRMVSPPTRPSPRFGHAMAYDPLRQEVV
LFGGYSGSSRNDTWVWNGSTWVLRTPSVSPPPRWGHTLTYDAARGRIVLFGGAQGTAGFYSDTWEWDGQTWIALSPTVRP
PARRNHAAAYDSLRGRVVLFGGYALQGETPTYFDDTWEWDGSRWQQVVARGPAARMGHTLFYDAVRQKSILFGGIGDDEL
SEVLWAWDGVSWTQLPDVPRPPVLSFHAAAYQLATCRALIVGGIPEREQLYVWQRAESSCSALPTARIDSVSPNPANRST
DRIQLIGSGFAANGSGRQINAYRWLINGAVLPGTTAHQTLNAADFAVGVYEVALAVRDSAGIWSAPVTQTLTIIDNPQIV
VATDPISATVVSGERTERLLPISNRGASPLTINLRVEAGTATASSHPTAATDTSWTLPRLYRPPDRLDARLAHFAQTTST
RHETYLVYMDEVADLRAAMQIEDWRERGRAIVRHLQEVAARSQAETLRYLEGQRRTGAVSFYWSLYSVNAIVVRGDAETL
RTLLAQPRVIGITISETYAIDEMPTGASPQSTGVRWNIRRIGADRVWNELGVRGEGVVVGSIDTGAKLDHPLLNANYRGR
YPDGSYDHSYSWFDPTGTFPDAPGDDNGHGTHTIGTMVGIDGIGVAPGARWIAARACSRRACQDIDILRAMEWMLAPYPS
TLGPVAANPDMRPQVVNNSWGGPGGRPLFQQMVAVWRAAGIFPAFAAGNCGQARPGCLVTGVGSVSSPGDYAESFATGAT
HDNDTLAAFSSQGPSRLTSNVKPDLVAPGVAIESAALNGGTLPQNGTSMASPHTAGAVALLLSLRPGLAIDQLEALLRTT
ARDLAAPGPDQQTGYGLLDVYAAAQAARTGLGWLRLPQTSGVIQPGQTLSIPIHFDGRGMPAGTYRAVLIIQSNDPSAAE
IRIPVSLIVQRVLRQSHPLITHRTADGMLIRWTAPDGRIARLEYAVQEGGPWIRQVGTASAIPGETLFVLRGLQPDTTYF
LRLIAMDGSIEDNGGRFYRVTTAPALPFAIDDIVTPVRIYVPLIQR
>Mature_1406_residues
MRRLLLLCTLIAILGSVLPVAVPRVAATQTIGWHSDVPVARQHHAMAANATEIFLFGGTVVDQNPQLQNDLWVWREGRWQ
WLGFGGPGPRSHTALAYDARRQELVLFGGWDGQTMLGDTWVWSAGGWQQRQPARSPSPRRAHAMVYDPQREQILLFGGYD
GRSRNDTWVWDGVTWTQLFPDSEPSTRHEHAMAYDAASRQIVLFGGASVTDFGSQILDDTWVWDGTSWVFQSPTTSPSAR
TDHILVTTTAGVLLFGGEDEQTLLDDTWLWHNHSWQRLTPSLSPLARSGAAAAFAPVQQRLLLFGGNGLFETYADTWFWN
GSTWQPLSGPSAPSSRTQTALADDVGRGTIVLFGGIDGEPLDDTWLWTAEQGWRMVSPPTRPSPRFGHAMAYDPLRQEVV
LFGGYSGSSRNDTWVWNGSTWVLRTPSVSPPPRWGHTLTYDAARGRIVLFGGAQGTAGFYSDTWEWDGQTWIALSPTVRP
PARRNHAAAYDSLRGRVVLFGGYALQGETPTYFDDTWEWDGSRWQQVVARGPAARMGHTLFYDAVRQKSILFGGIGDDEL
SEVLWAWDGVSWTQLPDVPRPPVLSFHAAAYQLATCRALIVGGIPEREQLYVWQRAESSCSALPTARIDSVSPNPANRST
DRIQLIGSGFAANGSGRQINAYRWLINGAVLPGTTAHQTLNAADFAVGVYEVALAVRDSAGIWSAPVTQTLTIIDNPQIV
VATDPISATVVSGERTERLLPISNRGASPLTINLRVEAGTATASSHPTAATDTSWTLPRLYRPPDRLDARLAHFAQTTST
RHETYLVYMDEVADLRAAMQIEDWRERGRAIVRHLQEVAARSQAETLRYLEGQRRTGAVSFYWSLYSVNAIVVRGDAETL
RTLLAQPRVIGITISETYAIDEMPTGASPQSTGVRWNIRRIGADRVWNELGVRGEGVVVGSIDTGAKLDHPLLNANYRGR
YPDGSYDHSYSWFDPTGTFPDAPGDDNGHGTHTIGTMVGIDGIGVAPGARWIAARACSRRACQDIDILRAMEWMLAPYPS
TLGPVAANPDMRPQVVNNSWGGPGGRPLFQQMVAVWRAAGIFPAFAAGNCGQARPGCLVTGVGSVSSPGDYAESFATGAT
HDNDTLAAFSSQGPSRLTSNVKPDLVAPGVAIESAALNGGTLPQNGTSMASPHTAGAVALLLSLRPGLAIDQLEALLRTT
ARDLAAPGPDQQTGYGLLDVYAAAQAARTGLGWLRLPQTSGVIQPGQTLSIPIHFDGRGMPAGTYRAVLIIQSNDPSAAE
IRIPVSLIVQRVLRQSHPLITHRTADGMLIRWTAPDGRIARLEYAVQEGGPWIRQVGTASAIPGETLFVLRGLQPDTTYF
LRLIAMDGSIEDNGGRFYRVTTAPALPFAIDDIVTPVRIYVPLIQR

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI21314675, Length=320, Percent_Identity=25.9375, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI76443679, Length=326, Percent_Identity=26.6871165644172, Blast_Score=71, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324576, Length=259, Percent_Identity=28.957528957529, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320775, Length=257, Percent_Identity=28.7937743190661, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129923, Length=372, Percent_Identity=23.6559139784946, Blast_Score=81, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24653126, Length=372, Percent_Identity=23.6559139784946, Blast_Score=81, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008969
- InterPro:   IPR014766
- InterPro:   IPR008985
- InterPro:   IPR012103
- InterPro:   IPR008757
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF05547 Peptidase_M6; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 153098; Mature: 153098

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS50853 FN3 ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLLLCTLIAILGSVLPVAVPRVAATQTIGWHSDVPVARQHHAMAANATEIFLFGGTV
CCHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCHHHHHHHEECCCEEEEEECCEE
VDQNPQLQNDLWVWREGRWQWLGFGGPGPRSHTALAYDARRQELVLFGGWDGQTMLGDTW
ECCCCCCCCCEEEEECCCEEEEECCCCCCCCCCEEEEECCCCEEEEEECCCCCEEECCEE
VWSAGGWQQRQPARSPSPRRAHAMVYDPQREQILLFGGYDGRSRNDTWVWDGVTWTQLFP
EECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEECCEEEEEECC
DSEPSTRHEHAMAYDAASRQIVLFGGASVTDFGSQILDDTWVWDGTSWVFQSPTTSPSAR
CCCCCCCHHHHEEECCCCCEEEEEECCCHHHHHHHHHCCCEEECCCCEEEECCCCCCCCC
TDHILVTTTAGVLLFGGEDEQTLLDDTWLWHNHSWQRLTPSLSPLARSGAAAAFAPVQQR
CCEEEEEEECCEEEECCCCCCEEECCEEEECCCCHHHCCCCCCHHHHCCCHHHHHHHHEE
LLLFGGNGLFETYADTWFWNGSTWQPLSGPSAPSSRTQTALADDVGRGTIVLFGGIDGEP
EEEECCCCCHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCC
LDDTWLWTAEQGWRMVSPPTRPSPRFGHAMAYDPLRQEVVLFGGYSGSSRNDTWVWNGST
CCCCEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCE
WVLRTPSVSPPPRWGHTLTYDAARGRIVLFGGAQGTAGFYSDTWEWDGQTWIALSPTVRP
EEEECCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCEEECCEEEEEECCCCCC
PARRNHAAAYDSLRGRVVLFGGYALQGETPTYFDDTWEWDGSRWQQVVARGPAARMGHTL
CCCCCCHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCHHH
FYDAVRQKSILFGGIGDDELSEVLWAWDGVSWTQLPDVPRPPVLSFHAAAYQLATCRALI
HHHHHHCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHE
VGGIPEREQLYVWQRAESSCSALPTARIDSVSPNPANRSTDRIQLIGSGFAANGSGRQIN
ECCCCCCCEEEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCEEEEEECCEECCCCCCEEE
AYRWLINGAVLPGTTAHQTLNAADFAVGVYEVALAVRDSAGIWSAPVTQTLTIIDNPQIV
EEEEEEECEECCCCCHHHHCCHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECCCEEE
VATDPISATVVSGERTERLLPISNRGASPLTINLRVEAGTATASSHPTAATDTSWTLPRL
EEECCCEEEEECCCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
YRPPDRLDARLAHFAQTTSTRHETYLVYMDEVADLRAAMQIEDWRERGRAIVRHLQEVAA
CCCHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSQAETLRYLEGQRRTGAVSFYWSLYSVNAIVVRGDAETLRTLLAQPRVIGITISETYAI
HHHHHHHHHHCCCCCCCEEEEEEEEEEEEEEEEECCHHHHHHHHCCCEEEEEEEECEEEE
DEMPTGASPQSTGVRWNIRRIGADRVWNELGVRGEGVVVGSIDTGAKLDHPLLNANYRGR
CCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCEECCCCCCC
YPDGSYDHSYSWFDPTGTFPDAPGDDNGHGTHTIGTMVGIDGIGVAPGARWIAARACSRR
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEHEECCCCCCCCCCHHHHHHHHHHHH
ACQDIDILRAMEWMLAPYPSTLGPVAANPDMRPQVVNNSWGGPGGRPLFQQMVAVWRAAG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHC
IFPAFAAGNCGQARPGCLVTGVGSVSSPGDYAESFATGATHDNDTLAAFSSQGPSRLTSN
CCHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHCC
VKPDLVAPGVAIESAALNGGTLPQNGTSMASPHTAGAVALLLSLRPGLAIDQLEALLRTT
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
ARDLAAPGPDQQTGYGLLDVYAAAQAARTGLGWLRLPQTSGVIQPGQTLSIPIHFDGRGM
HHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEEEECCCCC
PAGTYRAVLIIQSNDPSAAEIRIPVSLIVQRVLRQSHPLITHRTADGMLIRWTAPDGRIA
CCCCEEEEEEEECCCCCCEEEEECHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCEE
RLEYAVQEGGPWIRQVGTASAIPGETLFVLRGLQPDTTYFLRLIAMDGSIEDNGGRFYRV
EEEEEHHCCCCHHHHCCCCCCCCCCEEEEEECCCCCHHEEEEEEEECCCEECCCCEEEEE
TTAPALPFAIDDIVTPVRIYVPLIQR
EECCCCCEEHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MRRLLLLCTLIAILGSVLPVAVPRVAATQTIGWHSDVPVARQHHAMAANATEIFLFGGTV
CCHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCHHHHHHHEECCCEEEEEECCEE
VDQNPQLQNDLWVWREGRWQWLGFGGPGPRSHTALAYDARRQELVLFGGWDGQTMLGDTW
ECCCCCCCCCEEEEECCCEEEEECCCCCCCCCCEEEEECCCCEEEEEECCCCCEEECCEE
VWSAGGWQQRQPARSPSPRRAHAMVYDPQREQILLFGGYDGRSRNDTWVWDGVTWTQLFP
EECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEECCEEEEEECC
DSEPSTRHEHAMAYDAASRQIVLFGGASVTDFGSQILDDTWVWDGTSWVFQSPTTSPSAR
CCCCCCCHHHHEEECCCCCEEEEEECCCHHHHHHHHHCCCEEECCCCEEEECCCCCCCCC
TDHILVTTTAGVLLFGGEDEQTLLDDTWLWHNHSWQRLTPSLSPLARSGAAAAFAPVQQR
CCEEEEEEECCEEEECCCCCCEEECCEEEECCCCHHHCCCCCCHHHHCCCHHHHHHHHEE
LLLFGGNGLFETYADTWFWNGSTWQPLSGPSAPSSRTQTALADDVGRGTIVLFGGIDGEP
EEEECCCCCHHHHCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCC
LDDTWLWTAEQGWRMVSPPTRPSPRFGHAMAYDPLRQEVVLFGGYSGSSRNDTWVWNGST
CCCCEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCE
WVLRTPSVSPPPRWGHTLTYDAARGRIVLFGGAQGTAGFYSDTWEWDGQTWIALSPTVRP
EEEECCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCEEECCEEEEEECCCCCC
PARRNHAAAYDSLRGRVVLFGGYALQGETPTYFDDTWEWDGSRWQQVVARGPAARMGHTL
CCCCCCHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHCHHH
FYDAVRQKSILFGGIGDDELSEVLWAWDGVSWTQLPDVPRPPVLSFHAAAYQLATCRALI
HHHHHHCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHE
VGGIPEREQLYVWQRAESSCSALPTARIDSVSPNPANRSTDRIQLIGSGFAANGSGRQIN
ECCCCCCCEEEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCEEEEEECCEECCCCCCEEE
AYRWLINGAVLPGTTAHQTLNAADFAVGVYEVALAVRDSAGIWSAPVTQTLTIIDNPQIV
EEEEEEECEECCCCCHHHHCCHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECCCEEE
VATDPISATVVSGERTERLLPISNRGASPLTINLRVEAGTATASSHPTAATDTSWTLPRL
EEECCCEEEEECCCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
YRPPDRLDARLAHFAQTTSTRHETYLVYMDEVADLRAAMQIEDWRERGRAIVRHLQEVAA
CCCHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSQAETLRYLEGQRRTGAVSFYWSLYSVNAIVVRGDAETLRTLLAQPRVIGITISETYAI
HHHHHHHHHHCCCCCCCEEEEEEEEEEEEEEEEECCHHHHHHHHCCCEEEEEEEECEEEE
DEMPTGASPQSTGVRWNIRRIGADRVWNELGVRGEGVVVGSIDTGAKLDHPLLNANYRGR
CCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCEECCCCCCC
YPDGSYDHSYSWFDPTGTFPDAPGDDNGHGTHTIGTMVGIDGIGVAPGARWIAARACSRR
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEEHEECCCCCCCCCCHHHHHHHHHHHH
ACQDIDILRAMEWMLAPYPSTLGPVAANPDMRPQVVNNSWGGPGGRPLFQQMVAVWRAAG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHC
IFPAFAAGNCGQARPGCLVTGVGSVSSPGDYAESFATGATHDNDTLAAFSSQGPSRLTSN
CCHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHCC
VKPDLVAPGVAIESAALNGGTLPQNGTSMASPHTAGAVALLLSLRPGLAIDQLEALLRTT
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
ARDLAAPGPDQQTGYGLLDVYAAAQAARTGLGWLRLPQTSGVIQPGQTLSIPIHFDGRGM
HHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEEEECCCCC
PAGTYRAVLIIQSNDPSAAEIRIPVSLIVQRVLRQSHPLITHRTADGMLIRWTAPDGRIA
CCCCEEEEEEEECCCCCCEEEEECHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCEE
RLEYAVQEGGPWIRQVGTASAIPGETLFVLRGLQPDTTYFLRLIAMDGSIEDNGGRFYRV
EEEEEHHCCCCHHHHCCCCCCCCCCEEEEEECCCCCHHEEEEEEEECCCEECCCCEEEEE
TTAPALPFAIDDIVTPVRIYVPLIQR
EECCCCCEEHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2106512; 2118514; 2108961; 9384377; 3139638; 2106671 [H]