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The map label for this gene is ubiB [C]

Identifier: 222523966

GI number: 222523966

Start: 845762

End: 847435

Strand: Reverse

Name: ubiB [C]

Synonym: Chy400_0681

Alternate gene names: 222523966

Gene position: 847435-845762 (Counterclockwise)

Preceding gene: 222523967

Following gene: 222523963

Centisome position: 16.08

GC content: 58.12

Gene sequence:

>1674_bases
ATGTGGCCACTTGTTCGCCAGGCCCGTCATCTTGGACGCTACCGCGAAATTGCTCAGGTGCTGGTGCATCACGGTTTTGG
CTATCTGGTCGATCAGCTTGGGTTGAGTGGGCTGTTGTCGTTGCCCCGCCGGGTCATTTTGCGGGCACCGGCACCGCCAC
CACTCGGTAGTGCAGCCCGGCTGCGCGAGGCGCTGATCGAGCTGGGGCCGACGTTCGTCAAGCTGGGCCAGGCTTTGAGC
ACTCGTCCCGATCTTCTTCCAGCCGATGTGGTTGCCGAGCTGAGTAAGTTGCAGGATACGGTGCCGCCGTTTCCCGGCGA
TCAGGCGGTGGCCCTGATCGAAGCAACCTTTAATCGGCCACTTGATCAACTGTTTATTGCCTTTGATCGTCAGCCCTTTG
CCGCTGCCTCGCTTGGTCAGGTACACGCTGCCGTTCTGCCTGATGGAACGCAGGTGGTGGTCAAGGTGCAACGCCCGGAT
ATTGCCTCGCGCATTCAGACCGATCTGGCAATCCTGGCCGATCTGGCAACACTGGCACAGGAACGTCTGGCCTTCGCCGC
CCAATACAACCTGAGCGAGATTGTGTGGGAGTTTAGCGCCATGTTGCGCGCCGAGCTTGATTACGTCCGTGAAGGGCGCA
ATGCCGAGCGCTTCCGCCAGATGTTTTGCACAAATCCGCATATCTATATTCCGCGGGTGTATTGGGAATATACCGATAGC
CGTATCTTGACCACGGAGCGGATTGTTGGGGTTAAGCTAAACGATATGGCAGGATTGCGTGCTGCCGGGGTTGACATGTC
GCGCCTGGCGCGGGCAAGCCTTGATATTACGCTGGAAGAGATTTTTACCCACGGTTTCTTTCACAGCGATCCCCATCCGG
GCAACTTCTTCGTACTCGATGGTGACGTATTGGGAGTAGTTGATTTCGGGCAGGTAGGCACGCTTGATCACGCCACGATG
CAGGGCTTGCTCTGGCTGATGGGTGCGCTGGTCAATCACGATAGTCAGGGGCTGCTCAGATCACTCGAACGCCTGGAAGT
CATACCCCGGCGAGCGGCAAATCTGGCGTTGCGTCGCGATCTGGAACGGTTCGTCGAGGGATTTGTGGATCGGCCCCTCG
GCCTGATTTCGGCCCGCGAGACATTCGATGGCCTCACCACACTCCTACGGCGGCACCGTTTAACCATTCCCGGCCCTCTG
GCCACGTTGCTCAAGACCATTGTGATGATGGAGGGGTTGGGGATGCAACTTGATCCGAACCTGAATGTCTTCGCTGCCGC
CCGCCCGTACATTCAGCGCGCCCTTCGTGAGCAGATGAATCCAACCGCCCTCGGCGCTCAGGCGCTGGCAGGTGGTCGTG
AATTGGGTGAACTGGCGTTTGATCTACCCATCCAGATCAGTCAAACTCTCCAACACCTCAACGATGGCGAGTTGCGCATT
CAAACCCGCGAGCTTGAATTGCGCCGACTGGCCGCTGCGTTGATCGGTGCTGCCAATCGGCTGGCACTGGCGCTGGTTGT
TGCAGCGTTTATCGTAGGGGTAGCAGCATTGGTCATTGCAATGCGTGCTTTGGACTGGTATGGCGTGTTGCCGTGGACAC
TGTTGTTCATCGGGATTGGTGGCGTGATCACCGGCGGAATTATGTTGACGCTGGCGTTGCTACGTCGCGAATGA

Upstream 100 bases:

>100_bases
GAAGCCGGTTTGCTCACCTCTTGGTCTCGAAACCGGGGTATACTACACTTACTGCTGCGTTGTTCGCACGAGTTTCTGCC
TGTAGATAGCTGGTGTTCTC

Downstream 100 bases:

>100_bases
GGTGAGTGACCGGTAGTAGTATCCGGTCACTCTCCGGCAAGTAAGCGGTTAACGGTGGCAACAATCAATCGTCGCTCGAC
CGCCTTTATCCGTTCGTGCA

Product: ABC-1 domain-containing protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MWPLVRQARHLGRYREIAQVLVHHGFGYLVDQLGLSGLLSLPRRVILRAPAPPPLGSAARLREALIELGPTFVKLGQALS
TRPDLLPADVVAELSKLQDTVPPFPGDQAVALIEATFNRPLDQLFIAFDRQPFAAASLGQVHAAVLPDGTQVVVKVQRPD
IASRIQTDLAILADLATLAQERLAFAAQYNLSEIVWEFSAMLRAELDYVREGRNAERFRQMFCTNPHIYIPRVYWEYTDS
RILTTERIVGVKLNDMAGLRAAGVDMSRLARASLDITLEEIFTHGFFHSDPHPGNFFVLDGDVLGVVDFGQVGTLDHATM
QGLLWLMGALVNHDSQGLLRSLERLEVIPRRAANLALRRDLERFVEGFVDRPLGLISARETFDGLTTLLRRHRLTIPGPL
ATLLKTIVMMEGLGMQLDPNLNVFAAARPYIQRALREQMNPTALGAQALAGGRELGELAFDLPIQISQTLQHLNDGELRI
QTRELELRRLAAALIGAANRLALALVVAAFIVGVAALVIAMRALDWYGVLPWTLLFIGIGGVITGGIMLTLALLRRE

Sequences:

>Translated_557_residues
MWPLVRQARHLGRYREIAQVLVHHGFGYLVDQLGLSGLLSLPRRVILRAPAPPPLGSAARLREALIELGPTFVKLGQALS
TRPDLLPADVVAELSKLQDTVPPFPGDQAVALIEATFNRPLDQLFIAFDRQPFAAASLGQVHAAVLPDGTQVVVKVQRPD
IASRIQTDLAILADLATLAQERLAFAAQYNLSEIVWEFSAMLRAELDYVREGRNAERFRQMFCTNPHIYIPRVYWEYTDS
RILTTERIVGVKLNDMAGLRAAGVDMSRLARASLDITLEEIFTHGFFHSDPHPGNFFVLDGDVLGVVDFGQVGTLDHATM
QGLLWLMGALVNHDSQGLLRSLERLEVIPRRAANLALRRDLERFVEGFVDRPLGLISARETFDGLTTLLRRHRLTIPGPL
ATLLKTIVMMEGLGMQLDPNLNVFAAARPYIQRALREQMNPTALGAQALAGGRELGELAFDLPIQISQTLQHLNDGELRI
QTRELELRRLAAALIGAANRLALALVVAAFIVGVAALVIAMRALDWYGVLPWTLLFIGIGGVITGGIMLTLALLRRE
>Mature_557_residues
MWPLVRQARHLGRYREIAQVLVHHGFGYLVDQLGLSGLLSLPRRVILRAPAPPPLGSAARLREALIELGPTFVKLGQALS
TRPDLLPADVVAELSKLQDTVPPFPGDQAVALIEATFNRPLDQLFIAFDRQPFAAASLGQVHAAVLPDGTQVVVKVQRPD
IASRIQTDLAILADLATLAQERLAFAAQYNLSEIVWEFSAMLRAELDYVREGRNAERFRQMFCTNPHIYIPRVYWEYTDS
RILTTERIVGVKLNDMAGLRAAGVDMSRLARASLDITLEEIFTHGFFHSDPHPGNFFVLDGDVLGVVDFGQVGTLDHATM
QGLLWLMGALVNHDSQGLLRSLERLEVIPRRAANLALRRDLERFVEGFVDRPLGLISARETFDGLTTLLRRHRLTIPGPL
ATLLKTIVMMEGLGMQLDPNLNVFAAARPYIQRALREQMNPTALGAQALAGGRELGELAFDLPIQISQTLQHLNDGELRI
QTRELELRRLAAALIGAANRLALALVVAAFIVGVAALVIAMRALDWYGVLPWTLLFIGIGGVITGGIMLTLALLRRE

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=374, Percent_Identity=30.7486631016043, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI40254938, Length=291, Percent_Identity=32.6460481099656, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI217035081, Length=251, Percent_Identity=31.4741035856574, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI27363457, Length=258, Percent_Identity=30.2325581395349, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI217416386, Length=209, Percent_Identity=33.4928229665072, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI34147522, Length=443, Percent_Identity=25.5079006772009, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI2367309, Length=434, Percent_Identity=33.6405529953917, Blast_Score=210, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17559152, Length=244, Percent_Identity=31.9672131147541, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32565180, Length=243, Percent_Identity=31.2757201646091, Blast_Score=109, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321319, Length=241, Percent_Identity=31.1203319502075, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6325148, Length=437, Percent_Identity=23.3409610983982, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323282, Length=241, Percent_Identity=28.6307053941909, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24662575, Length=362, Percent_Identity=30.3867403314917, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI22024280, Length=227, Percent_Identity=32.5991189427313, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI18859849, Length=309, Percent_Identity=28.4789644012945, Blast_Score=115, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 61454; Mature: 61454

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWPLVRQARHLGRYREIAQVLVHHGFGYLVDQLGLSGLLSLPRRVILRAPAPPPLGSAAR
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHH
LREALIELGPTFVKLGQALSTRPDLLPADVVAELSKLQDTVPPFPGDQAVALIEATFNRP
HHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
LDQLFIAFDRQPFAAASLGQVHAAVLPDGTQVVVKVQRPDIASRIQTDLAILADLATLAQ
HHHHHHHHCCCCCHHHHHHHHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
ERLAFAAQYNLSEIVWEFSAMLRAELDYVREGRNAERFRQMFCTNPHIYIPRVYWEYTDS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECEEEEEECCC
RILTTERIVGVKLNDMAGLRAAGVDMSRLARASLDITLEEIFTHGFFHSDPHPGNFFVLD
EEEEHHHEEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
GDVLGVVDFGQVGTLDHATMQGLLWLMGALVNHDSQGLLRSLERLEVIPRRAANLALRRD
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LERFVEGFVDRPLGLISARETFDGLTTLLRRHRLTIPGPLATLLKTIVMMEGLGMQLDPN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCC
LNVFAAARPYIQRALREQMNPTALGAQALAGGRELGELAFDLPIQISQTLQHLNDGELRI
CCEEECCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCCEEE
QTRELELRRLAAALIGAANRLALALVVAAFIVGVAALVIAMRALDWYGVLPWTLLFIGIG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVITGGIMLTLALLRRE
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWPLVRQARHLGRYREIAQVLVHHGFGYLVDQLGLSGLLSLPRRVILRAPAPPPLGSAAR
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHH
LREALIELGPTFVKLGQALSTRPDLLPADVVAELSKLQDTVPPFPGDQAVALIEATFNRP
HHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
LDQLFIAFDRQPFAAASLGQVHAAVLPDGTQVVVKVQRPDIASRIQTDLAILADLATLAQ
HHHHHHHHCCCCCHHHHHHHHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
ERLAFAAQYNLSEIVWEFSAMLRAELDYVREGRNAERFRQMFCTNPHIYIPRVYWEYTDS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECEEEEEECCC
RILTTERIVGVKLNDMAGLRAAGVDMSRLARASLDITLEEIFTHGFFHSDPHPGNFFVLD
EEEEHHHEEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
GDVLGVVDFGQVGTLDHATMQGLLWLMGALVNHDSQGLLRSLERLEVIPRRAANLALRRD
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LERFVEGFVDRPLGLISARETFDGLTTLLRRHRLTIPGPLATLLKTIVMMEGLGMQLDPN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCC
LNVFAAARPYIQRALREQMNPTALGAQALAGGRELGELAFDLPIQISQTLQHLNDGELRI
CCEEECCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCCCEEE
QTRELELRRLAAALIGAANRLALALVVAAFIVGVAALVIAMRALDWYGVLPWTLLFIGIG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVITGGIMLTLALLRRE
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]