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The map label for this gene is ttuD [H]

Identifier: 222523954

GI number: 222523954

Start: 829245

End: 830606

Strand: Reverse

Name: ttuD [H]

Synonym: Chy400_0669

Alternate gene names: 222523954

Gene position: 830606-829245 (Counterclockwise)

Preceding gene: 222523955

Following gene: 222523950

Centisome position: 15.76

GC content: 64.9

Gene sequence:

>1362_bases
ATGTCTGAGCGATTGTTGACGGCGTCGCTGCGGGCGGCCTGGTGGGGACCTGCGGTTACGCGGATCATGGCTGCTGCCCT
GGCCGCGGCTGATCCGTTCCAGGCCACGCTCACCGCTCTGCAGCGCGACGGCGACTGGCTGATGGTCGGCGAGCGCCGCT
ACGATCTGCGGGCGTTTCAGCGTATCTGGCTGGTCGGTGCGGGCAAAGCCGGTGCAGCAATGGCACAGGCTGCGGTTCAG
GTACTGGGAGATCGCCTGCACGGCGGCCTGGTCGTCGTGAAAGATGACGGTGCCCCACTGCCTGACCTGCCGGGTATCAC
CCTGCTACGCGCCGCCCACCCGACCCCAGACGAACGGAGTGTACTGGCCGGTCAGCAACTCGCGACCTTGCTCGCCGGGG
TCACCGCACACGACCTGGTCCTGGCCCTGATTTCCGGTGGTGGTTCAGCACTGCTCAACCTGCCGGTACCGGGGGTCACC
CTGGCCGACATTCAGATCCTCACTGCCGAACTACTGGCCTGTGGCGCACCGATTGGCGCTATCAACACCCTGCGCAAGCA
TCTCGATCAGATCAAAGGTGGCGGACTGGCGCGCATGGCGGCACCGGCAACACTCATTACCCTCATCCTCTCCGACGTTG
TCGGTAGCCCACTTCAGGTCATCGCCTCCGGGCCAACCGTCGCCGATCCAACCACCTTTGCCGACGCCCTGGCGTTTCTC
GAACAGTACGAATTAATGGAACGGTGTCCACCGGCTATCCTGACGTATCTGATGGCAGGTTCCCGTGGCGACCATCCAGA
GACATTGAAACCGGGCGATCCCTTGCTCACGACGGTGCAGAACATTCTCATCGGGAGCAACGCTCAGGCCGCCCAGGCCG
CACTTATTGCCGCCCGCGACGCCGGCTTCAACGCAATGCTCCTGACCACCTACCTGGAGGGAGAAGCTCGCGAGGTGGGG
CACGTGCTGGCCGGCATTGCCCGCGAAATTGCCACATCCGGCCATCCACTGGCAACGCCGGCCTGCGTGATTGCCGGCGG
CGAAACAACCGTAACCCTGCGTGGAACCGGATTGGGCGGACGGAACCAGGAGCTGGCGTTGAGTGCCGCCATCGCCCTCG
ACGGCCTCGACCAGGCCGCCGTCATTGCCCTGGCAACCGATGGCGGCGACGGACCAACCGATGCTGCCGGCGCAGTTGCC
ACCGGCACAACCGTCGCTCGTGCCAGAGCGATAGGCCACGATCCACTCACTCACCTGCGGCGCAACGACGCCTACCCCTT
CTTCGCCGCCCTCGACGATCTCCTGCGCCCCGGCCCAACCGGCACCAACGTCAACGATCTGGTGTTTATTGTGGTCGGAT
GA

Upstream 100 bases:

>100_bases
AACGCCGGCAGCATGCACGAGGCGAAAAAAGCAGGGCTGGTACGGATGGAAGGCAAGCAGTACATTGTGCAAGATGGAGA
CATTTGCCACTTCCTCTTCA

Downstream 100 bases:

>100_bases
CAGCTTCATCCAGCGGTTTCAGCCTTCTGCGCTATAGCATGCCCGCCATCCACCCCTGCGGCCTCGTCACACGCGAGAGC
GTTTCCCGCTTTCGATATGG

Product: Hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSERLLTASLRAAWWGPAVTRIMAAALAAADPFQATLTALQRDGDWLMVGERRYDLRAFQRIWLVGAGKAGAAMAQAAVQ
VLGDRLHGGLVVVKDDGAPLPDLPGITLLRAAHPTPDERSVLAGQQLATLLAGVTAHDLVLALISGGGSALLNLPVPGVT
LADIQILTAELLACGAPIGAINTLRKHLDQIKGGGLARMAAPATLITLILSDVVGSPLQVIASGPTVADPTTFADALAFL
EQYELMERCPPAILTYLMAGSRGDHPETLKPGDPLLTTVQNILIGSNAQAAQAALIAARDAGFNAMLLTTYLEGEAREVG
HVLAGIAREIATSGHPLATPACVIAGGETTVTLRGTGLGGRNQELALSAAIALDGLDQAAVIALATDGGDGPTDAAGAVA
TGTTVARARAIGHDPLTHLRRNDAYPFFAALDDLLRPGPTGTNVNDLVFIVVG

Sequences:

>Translated_453_residues
MSERLLTASLRAAWWGPAVTRIMAAALAAADPFQATLTALQRDGDWLMVGERRYDLRAFQRIWLVGAGKAGAAMAQAAVQ
VLGDRLHGGLVVVKDDGAPLPDLPGITLLRAAHPTPDERSVLAGQQLATLLAGVTAHDLVLALISGGGSALLNLPVPGVT
LADIQILTAELLACGAPIGAINTLRKHLDQIKGGGLARMAAPATLITLILSDVVGSPLQVIASGPTVADPTTFADALAFL
EQYELMERCPPAILTYLMAGSRGDHPETLKPGDPLLTTVQNILIGSNAQAAQAALIAARDAGFNAMLLTTYLEGEAREVG
HVLAGIAREIATSGHPLATPACVIAGGETTVTLRGTGLGGRNQELALSAAIALDGLDQAAVIALATDGGDGPTDAAGAVA
TGTTVARARAIGHDPLTHLRRNDAYPFFAALDDLLRPGPTGTNVNDLVFIVVG
>Mature_452_residues
SERLLTASLRAAWWGPAVTRIMAAALAAADPFQATLTALQRDGDWLMVGERRYDLRAFQRIWLVGAGKAGAAMAQAAVQV
LGDRLHGGLVVVKDDGAPLPDLPGITLLRAAHPTPDERSVLAGQQLATLLAGVTAHDLVLALISGGGSALLNLPVPGVTL
ADIQILTAELLACGAPIGAINTLRKHLDQIKGGGLARMAAPATLITLILSDVVGSPLQVIASGPTVADPTTFADALAFLE
QYELMERCPPAILTYLMAGSRGDHPETLKPGDPLLTTVQNILIGSNAQAAQAALIAARDAGFNAMLLTTYLEGEAREVGH
VLAGIAREIATSGHPLATPACVIAGGETTVTLRGTGLGGRNQELALSAAIALDGLDQAAVIALATDGGDGPTDAAGAVAT
GTTVARARAIGHDPLTHLRRNDAYPFFAALDDLLRPGPTGTNVNDLVFIVVG

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=523, Percent_Identity=38.4321223709369, Blast_Score=228, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI193205461, Length=468, Percent_Identity=31.4102564102564, Blast_Score=171, Evalue=7e-43,
Organism=Drosophila melanogaster, GI19920578, Length=436, Percent_Identity=33.4862385321101, Blast_Score=166, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 46456; Mature: 46325

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLLTASLRAAWWGPAVTRIMAAALAAADPFQATLTALQRDGDWLMVGERRYDLRAFQ
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCHHHHHHH
RIWLVGAGKAGAAMAQAAVQVLGDRLHGGLVVVKDDGAPLPDLPGITLLRAAHPTPDERS
HHHEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCHH
VLAGQQLATLLAGVTAHDLVLALISGGGSALLNLPVPGVTLADIQILTAELLACGAPIGA
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHH
INTLRKHLDQIKGGGLARMAAPATLITLILSDVVGSPLQVIASGPTVADPTTFADALAFL
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHH
EQYELMERCPPAILTYLMAGSRGDHPETLKPGDPLLTTVQNILIGSNAQAAQAALIAARD
HHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHEEECC
AGFNAMLLTTYLEGEAREVGHVLAGIAREIATSGHPLATPACVIAGGETTVTLRGTGLGG
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCC
RNQELALSAAIALDGLDQAAVIALATDGGDGPTDAAGAVATGTTVARARAIGHDPLTHLR
CCCHHHEEHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHCCHHHHHHHHCCCCHHHHHH
RNDAYPFFAALDDLLRPGPTGTNVNDLVFIVVG
CCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SERLLTASLRAAWWGPAVTRIMAAALAAADPFQATLTALQRDGDWLMVGERRYDLRAFQ
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCHHHHHHH
RIWLVGAGKAGAAMAQAAVQVLGDRLHGGLVVVKDDGAPLPDLPGITLLRAAHPTPDERS
HHHEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCHH
VLAGQQLATLLAGVTAHDLVLALISGGGSALLNLPVPGVTLADIQILTAELLACGAPIGA
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHH
INTLRKHLDQIKGGGLARMAAPATLITLILSDVVGSPLQVIASGPTVADPTTFADALAFL
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHH
EQYELMERCPPAILTYLMAGSRGDHPETLKPGDPLLTTVQNILIGSNAQAAQAALIAARD
HHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHEEECC
AGFNAMLLTTYLEGEAREVGHVLAGIAREIATSGHPLATPACVIAGGETTVTLRGTGLGG
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCC
RNQELALSAAIALDGLDQAAVIALATDGGDGPTDAAGAVATGTTVARARAIGHDPLTHLR
CCCHHHEEHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHCCHHHHHHHHCCCCHHHHHH
RNDAYPFFAALDDLLRPGPTGTNVNDLVFIVVG
CCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]