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The map label for this gene is acoC [H]

Identifier: 222523843

GI number: 222523843

Start: 658496

End: 659380

Strand: Reverse

Name: acoC [H]

Synonym: Chy400_0551

Alternate gene names: 222523843

Gene position: 659380-658496 (Counterclockwise)

Preceding gene: 222523848

Following gene: 222523842

Centisome position: 12.51

GC content: 57.85

Gene sequence:

>885_bases
ATGTCAACATCTTCAACACTCTGGGAAATTGAAAGTCCACTCGGTCCGGTCGCCTTTCGGGTTTCCGGGCAGGGGCGTCC
TCTGATCTTTATCCACGGCTGGGGTGCTTCCAGCCGTTACTGGCAGGCGGCACCAGCGTTCTTACCCAACCGGCGCCTGA
TCGCAATTGACCTTCCCGGTTGTGGCGCATCTCCGGCACCGCTCGAACCGGTTTCTCTGGAGTCGTCTGCGCGGGCGGTG
CTGGCAGTGGCCGATGCTCTGGATATTGATCGATTTGCATTAGTGGGCCATTCTCTCGGCGCCGCAGTGGCGCTTGCTGT
CGCTGGTCTGGCCGGTGCACGGGTAGAGCGTCTCGGCCTGGTGAGTTTTGGGATTGGCGCTAACCTGTACGAGGATGCAC
TGGTCACGCTGGCCGGCGCACAGTGGCAGGTGGCTGCGGCTTACTGGCGACCATTGCTGGTATGGTGGCGTCCCTGGTGG
GAATATACCTCTACCTGGCGACAGGCACTCTGGGCATTGCCACCAACGCCGGACCTCCTGGCGCGACCGCTGGTGCGACA
ACCGCTTGACCGTTCATTGCTGGCGCAAGGCATTGCCGATCTGGCGGCAATGGATCCGCTGGTAGCTATCGAGACCGCAG
CCATTATGGGACATCCCCGTCTGAAACGACTATTGCAACTTCCATTACCGCCGGTTGTTCTGATTAGTGGCAGTGACGAT
CCGGTCTTTCCACCGGTCAATGTCGAGATGCTCAGTCGTGTTTTACCGGATGTACAGGTGGTCTTCATTCCCAATTGTGG
TCATGTACCTATGGTTGAGGAACCGGCAGCATGTTATCAGACAATTGCTCGCTTTCTGGATGGAGAAAACGACTATTTGT
CGTAA

Upstream 100 bases:

>100_bases
CATCCATCATCATACAGCCTTTCAACGCTGGATGAGACAAATGTCAATGCCTGTAACTGTCTGGGATTATAGTGGATATT
GCAAACAGAGGAGGTTTGTC

Downstream 100 bases:

>100_bases
GGTTACTAAAATAGTGTGAATTATCAAGCGCAGTATTGTTCTCTGGACATAGACTGTGAGGCTAATCTTACTGAAGGTAC
TAAAAGTATCATGCAATCTG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSTSSTLWEIESPLGPVAFRVSGQGRPLIFIHGWGASSRYWQAAPAFLPNRRLIAIDLPGCGASPAPLEPVSLESSARAV
LAVADALDIDRFALVGHSLGAAVALAVAGLAGARVERLGLVSFGIGANLYEDALVTLAGAQWQVAAAYWRPLLVWWRPWW
EYTSTWRQALWALPPTPDLLARPLVRQPLDRSLLAQGIADLAAMDPLVAIETAAIMGHPRLKRLLQLPLPPVVLISGSDD
PVFPPVNVEMLSRVLPDVQVVFIPNCGHVPMVEEPAACYQTIARFLDGENDYLS

Sequences:

>Translated_294_residues
MSTSSTLWEIESPLGPVAFRVSGQGRPLIFIHGWGASSRYWQAAPAFLPNRRLIAIDLPGCGASPAPLEPVSLESSARAV
LAVADALDIDRFALVGHSLGAAVALAVAGLAGARVERLGLVSFGIGANLYEDALVTLAGAQWQVAAAYWRPLLVWWRPWW
EYTSTWRQALWALPPTPDLLARPLVRQPLDRSLLAQGIADLAAMDPLVAIETAAIMGHPRLKRLLQLPLPPVVLISGSDD
PVFPPVNVEMLSRVLPDVQVVFIPNCGHVPMVEEPAACYQTIARFLDGENDYLS
>Mature_293_residues
STSSTLWEIESPLGPVAFRVSGQGRPLIFIHGWGASSRYWQAAPAFLPNRRLIAIDLPGCGASPAPLEPVSLESSARAVL
AVADALDIDRFALVGHSLGAAVALAVAGLAGARVERLGLVSFGIGANLYEDALVTLAGAQWQVAAAYWRPLLVWWRPWWE
YTSTWRQALWALPPTPDLLARPLVRQPLDRSLLAQGIADLAAMDPLVAIETAAIMGHPRLKRLLQLPLPPVVLISGSDDP
VFPPVNVEMLSRVLPDVQVVFIPNCGHVPMVEEPAACYQTIARFLDGENDYLS

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 31771; Mature: 31640

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSSTLWEIESPLGPVAFRVSGQGRPLIFIHGWGASSRYWQAAPAFLPNRRLIAIDLPG
CCCCCCEEEECCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCC
CGASPAPLEPVSLESSARAVLAVADALDIDRFALVGHSLGAAVALAVAGLAGARVERLGL
CCCCCCCCCCCCCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VSFGIGANLYEDALVTLAGAQWQVAAAYWRPLLVWWRPWWEYTSTWRQALWALPPTPDLL
EEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHH
ARPLVRQPLDRSLLAQGIADLAAMDPLVAIETAAIMGHPRLKRLLQLPLPPVVLISGSDD
HHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCC
PVFPPVNVEMLSRVLPDVQVVFIPNCGHVPMVEEPAACYQTIARFLDGENDYLS
CCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
STSSTLWEIESPLGPVAFRVSGQGRPLIFIHGWGASSRYWQAAPAFLPNRRLIAIDLPG
CCCCCEEEECCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCC
CGASPAPLEPVSLESSARAVLAVADALDIDRFALVGHSLGAAVALAVAGLAGARVERLGL
CCCCCCCCCCCCCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VSFGIGANLYEDALVTLAGAQWQVAAAYWRPLLVWWRPWWEYTSTWRQALWALPPTPDLL
EEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHH
ARPLVRQPLDRSLLAQGIADLAAMDPLVAIETAAIMGHPRLKRLLQLPLPPVVLISGSDD
HHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCC
PVFPPVNVEMLSRVLPDVQVVFIPNCGHVPMVEEPAACYQTIARFLDGENDYLS
CCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]