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The map label for this gene is add [H]

Identifier: 222523832

GI number: 222523832

Start: 645167

End: 646207

Strand: Reverse

Name: add [H]

Synonym: Chy400_0540

Alternate gene names: 222523832

Gene position: 646207-645167 (Counterclockwise)

Preceding gene: 222523836

Following gene: 222523827

Centisome position: 12.26

GC content: 56.39

Gene sequence:

>1041_bases
ATGCTGACGGCTGAACTGGCGGCGTTCATTGAGCGTATGCCCAAAGTTGAACTTCATCTTCATCTGGAAGGTGCGGTGAT
GCCGCAGACCTTTTTGGCTTTGAGTCGGCGTAATAATATCTCCCTCCCAGTGCAGACCGAAGAAGAACTGCTTGCCCTCT
TCCACTACGACGATTTTCACAATTTTCTGGAAACATTTATGGCCCTGGCGGCAACCATCGTTTCCGGTGAGGATTTTGAA
TTACTGGCGTTTGAGCTGGGAATGGCCCTGGCCCGTCAATACGTGGCTTACGCTGAAGTCATGATTTCGCCGATGCAACA
TGTTCGGCGGGGCGTTGATCTCCGCGAAGCGCTGGCCGGAGCAGCATCCGGTTTTGCGCGTGCCAGGCGTCAGGGCGGAC
CTCACGTTGGGATTGTGCTTGACTATGGCCGACAATACGGCGCCGAGGCAGCCTGGCCGATCCTCGAAACGGCCATCGCC
TGTCGTTCGCTCGGTGTGGTGGGATGGTCGATTGGCGGTAATGAAATTGGTCATCCGCCGGAAGAGTTTGCCGAGTTGTT
TGCGGCTGCCCGTCGTGCAGGTTTAGGGTTGATGGCGCACGCCGGTGAAGTTGTTGGGCCGGCCAGTGTTTGGGGGGCAA
TTGATGTACTGGAGGTTTCTCGTATTGGTCACGGCATTCGCAGTGTAGAAGACCCGCTCTTACTGAAAGCACTGGCCGAG
CGTGACGTGGTGCTCGATGTCTGTCCGAGCAGCAATATCCGCACGAAAGCTGTCACGTCCTGGCAAACCCACCCGTTGCG
TCAATTGTACAATGCCGGTGTGCCGGTTACCATCAATTCTGATGACCCAACATTCTTCGAGACAACGCTGAGCGAAGAGT
TTCGGCGGATCGCTCACCATTTCGGCTTCACGGCGGATGATTTTTGCCGTATGACGCTCACGGCTGTCCGGGCCACATTC
TTGTCACCGGCAGAGCGTGATGCGCTGCTGACAACCGTCGCTCAGGAACAGCAGCGATTGCGTGCAGCGTTGGGGGTGTA
G

Upstream 100 bases:

>100_bases
GAGCTGAATTTCAGAACGTACTTGCTCATTTCGTTGTTTCGTCGCACTGCAATATCCGGTACAATACCGTACATCTGCGT
TTTGGAAAGGGGGCGAGATT

Downstream 100 bases:

>100_bases
CGGCATGCCTGACCGTAGCATCCCGGAGATTGCGTTGTCTGGCGTGCGGAAGGGTGATTTCTGCACCTACCATGCTCGAC
GGTGGGCGCGCATCGCACTG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MLTAELAAFIERMPKVELHLHLEGAVMPQTFLALSRRNNISLPVQTEEELLALFHYDDFHNFLETFMALAATIVSGEDFE
LLAFELGMALARQYVAYAEVMISPMQHVRRGVDLREALAGAASGFARARRQGGPHVGIVLDYGRQYGAEAAWPILETAIA
CRSLGVVGWSIGGNEIGHPPEEFAELFAAARRAGLGLMAHAGEVVGPASVWGAIDVLEVSRIGHGIRSVEDPLLLKALAE
RDVVLDVCPSSNIRTKAVTSWQTHPLRQLYNAGVPVTINSDDPTFFETTLSEEFRRIAHHFGFTADDFCRMTLTAVRATF
LSPAERDALLTTVAQEQQRLRAALGV

Sequences:

>Translated_346_residues
MLTAELAAFIERMPKVELHLHLEGAVMPQTFLALSRRNNISLPVQTEEELLALFHYDDFHNFLETFMALAATIVSGEDFE
LLAFELGMALARQYVAYAEVMISPMQHVRRGVDLREALAGAASGFARARRQGGPHVGIVLDYGRQYGAEAAWPILETAIA
CRSLGVVGWSIGGNEIGHPPEEFAELFAAARRAGLGLMAHAGEVVGPASVWGAIDVLEVSRIGHGIRSVEDPLLLKALAE
RDVVLDVCPSSNIRTKAVTSWQTHPLRQLYNAGVPVTINSDDPTFFETTLSEEFRRIAHHFGFTADDFCRMTLTAVRATF
LSPAERDALLTTVAQEQQRLRAALGV
>Mature_346_residues
MLTAELAAFIERMPKVELHLHLEGAVMPQTFLALSRRNNISLPVQTEEELLALFHYDDFHNFLETFMALAATIVSGEDFE
LLAFELGMALARQYVAYAEVMISPMQHVRRGVDLREALAGAASGFARARRQGGPHVGIVLDYGRQYGAEAAWPILETAIA
CRSLGVVGWSIGGNEIGHPPEEFAELFAAARRAGLGLMAHAGEVVGPASVWGAIDVLEVSRIGHGIRSVEDPLLLKALAE
RDVVLDVCPSSNIRTKAVTSWQTHPLRQLYNAGVPVTINSDDPTFFETTLSEEFRRIAHHFGFTADDFCRMTLTAVRATF
LSPAERDALLTTVAQEQQRLRAALGV

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=343, Percent_Identity=28.8629737609329, Blast_Score=133, Evalue=2e-31,
Organism=Escherichia coli, GI1787910, Length=330, Percent_Identity=31.5151515151515, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32565969, Length=341, Percent_Identity=31.3782991202346, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17538512, Length=342, Percent_Identity=31.2865497076023, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI115537133, Length=332, Percent_Identity=25, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324188, Length=336, Percent_Identity=29.4642857142857, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24645260, Length=331, Percent_Identity=26.2839879154079, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37903; Mature: 37903

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAELAAFIERMPKVELHLHLEGAVMPQTFLALSRRNNISLPVQTEEELLALFHYDDFH
CCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
NFLETFMALAATIVSGEDFELLAFELGMALARQYVAYAEVMISPMQHVRRGVDLREALAG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AASGFARARRQGGPHVGIVLDYGRQYGAEAAWPILETAIACRSLGVVGWSIGGNEIGHPP
HHHHHHHHHHCCCCEEEEEEECCHHCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCH
EEFAELFAAARRAGLGLMAHAGEVVGPASVWGAIDVLEVSRIGHGIRSVEDPLLLKALAE
HHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC
RDVVLDVCPSSNIRTKAVTSWQTHPLRQLYNAGVPVTINSDDPTFFETTLSEEFRRIAHH
CCEEEEECCCCCCCHHEECCCCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHH
FGFTADDFCRMTLTAVRATFLSPAERDALLTTVAQEQQRLRAALGV
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTAELAAFIERMPKVELHLHLEGAVMPQTFLALSRRNNISLPVQTEEELLALFHYDDFH
CCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
NFLETFMALAATIVSGEDFELLAFELGMALARQYVAYAEVMISPMQHVRRGVDLREALAG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AASGFARARRQGGPHVGIVLDYGRQYGAEAAWPILETAIACRSLGVVGWSIGGNEIGHPP
HHHHHHHHHHCCCCEEEEEEECCHHCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCH
EEFAELFAAARRAGLGLMAHAGEVVGPASVWGAIDVLEVSRIGHGIRSVEDPLLLKALAE
HHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC
RDVVLDVCPSSNIRTKAVTSWQTHPLRQLYNAGVPVTINSDDPTFFETTLSEEFRRIAHH
CCEEEEECCCCCCCHHEECCCCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHH
FGFTADDFCRMTLTAVRATFLSPAERDALLTTVAQEQQRLRAALGV
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA