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The map label for this gene is ychM [C]

Identifier: 222523539

GI number: 222523539

Start: 291415

End: 293181

Strand: Direct

Name: ychM [C]

Synonym: Chy400_0245

Alternate gene names: 222523539

Gene position: 291415-293181 (Clockwise)

Preceding gene: 222523538

Following gene: 222523540

Centisome position: 5.53

GC content: 57.56

Gene sequence:

>1767_bases
ATGACGCCCGTTTCAGCTCATCGGCCCGATGTGCAGGCAGCGTTGCTGGCGATGATCTATCGCTATCTCCCATTCCTCAA
CTGGCTGCGCCATTATCGTCGTGAACACCTGCCGAGCGATGTGGTTGCGGGCATTGTGACGGCGATCATGCTCATTCCCC
AAAGCATGGCCTACGCTCAACTGGCCGGTCTGCCCCCACAGATCGGCCTCTATGCCTCTGTTGCACCACTCATTGTCTAC
GCGCTTCTCGGCACCTCCGGCCAGCTCTCGGTCGGCCCTGTTGCCATCACCTCGCTCCTCGTGTTTAGCGGTGTCAGCAG
TCTGGCCGAGCCAGGCAGCGCACGTTACATCCAGCTAGTGCTGTTACTGGCGTTCATGGTTGGTGCGATCAAGCTGACAT
TTGGTGTGCTCCGGTTGGGAGCGATCCTAAACTTTATTTCGCATCCAGTACTGACAGCGTTTACCAGTGCCTCCGCACTG
ATTATTGCTGTTGGTCAGCTCAAATATATTCTCGGCTACCGCATCGGCGGCGAACACATCCACGAGACCATCGGCCAGGC
AATTGCCGGTTTAAGCCAGACGAATCTGGTCACACTGACCATCGGTCTGGTCAGCATTGGCCTCCTCGTCTTTTTCCGTC
AGGGTTTACGGCCCCTGCTACGCCGGACAGGTCTCCCACCATTGGCGATCACGCTGATTGTAAGCGGCGCACCGCTGCTC
ACCGTCATCCTGGGCATCCTGGTCGCCCAAACCCTCTTCCTGGATCAAACAGCCGGCATTGCGGTAGTAGGAGCAATTCC
GGCGGGTCTCTCGCCAATCAGTGTACCGGCATTTTCCATGGCCGATGCGCAGGCGCTCCTGCCAACCGCCCTGACCATCG
TGCTGGTCAGTGTCGTCGAGTCTATTGCGGTAGCGAAGGCCCTGGCCAGTAAACGCCGGCAGGCTATCGATCCCGATCAG
GAACTGGTAGCACTGGGAGCTGCCAACATCACTGCCAGCTTCTTCAGCGGCTATCCGGTTACCGGTGGCTTTGCCCGCTC
GGTGGTGAATGCACAGGCCGGCGCCATCACCGGTCTGGCGTCACTCATCACTGCCCTCGGAATCGCGGTGATTCTGCTCT
TCTTCACCCCAGTCTTCTACTATCTGCCGCAGGCAGTCCTGGCCGCCACTGTCATCGTCGCCGTTATCGGATTGGTCGAT
CTGCGTGAACCCCGCCGTATCTGGCGCACCAACCGTGGCGATGCCTTCACCTGGTTGATCACATTCCTGGCGGTCCTCAC
CCTGGGCATCGAGACCGGCATCTTCGTCGGAGTTGCCTCGGCGCTCATCCTCTACCTCTGGCGCACAAGCCGCCCTCATA
TCGCGATTGTGGGTCGGTTAGGTGACAGTGAAGTGTACCGCAACGTCGAACGGTATCAGGTCAAAACGTGGCCGCACGTA
GTGGCAGTGCGGGTTGATGAGAGCCTCTACTTTGCCAATACCCGCTACCTCGAAAGTGCCCTGTTGCAGATTGTTGCTGA
ACGACCATCGGTAAAACACCTTGTGTTGATCGGCTCAGCGATTAACTTTATCGACTCCAGTGCACTCCATACGCTCGAAC
ATCTCATTGACGAACTGCGCGATGCCGGCGTCGAATTCCATCTGGCCGACATCAAAGGGCCGGTAATGGATCGGCTCAAG
CAATCAGAATTGATTGACAAAATCGGTCACGACCATATTCATCTGACGACCCATACCGCTATGCTGGCATTGGGTTGCCA
GGATTAG

Upstream 100 bases:

>100_bases
TGCGGGCAGCCGGTTACGACGATGATGCCATCGAGACCTTCGATTTCTGCGCCGGCGATTTCTTTGAACGGGTCGGGTCA
CAGGCATAGGGAGGGGAATT

Downstream 100 bases:

>100_bases
CAGCTTATCAAAAGCACCACTCTGCGAGTGGGTGAAGGCAACACCTTCGCCCACTCATTGAGTAGCTCTATGCCGAAAGG
TTTTCGACCATGAAATACCG

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MTPVSAHRPDVQAALLAMIYRYLPFLNWLRHYRREHLPSDVVAGIVTAIMLIPQSMAYAQLAGLPPQIGLYASVAPLIVY
ALLGTSGQLSVGPVAITSLLVFSGVSSLAEPGSARYIQLVLLLAFMVGAIKLTFGVLRLGAILNFISHPVLTAFTSASAL
IIAVGQLKYILGYRIGGEHIHETIGQAIAGLSQTNLVTLTIGLVSIGLLVFFRQGLRPLLRRTGLPPLAITLIVSGAPLL
TVILGILVAQTLFLDQTAGIAVVGAIPAGLSPISVPAFSMADAQALLPTALTIVLVSVVESIAVAKALASKRRQAIDPDQ
ELVALGAANITASFFSGYPVTGGFARSVVNAQAGAITGLASLITALGIAVILLFFTPVFYYLPQAVLAATVIVAVIGLVD
LREPRRIWRTNRGDAFTWLITFLAVLTLGIETGIFVGVASALILYLWRTSRPHIAIVGRLGDSEVYRNVERYQVKTWPHV
VAVRVDESLYFANTRYLESALLQIVAERPSVKHLVLIGSAINFIDSSALHTLEHLIDELRDAGVEFHLADIKGPVMDRLK
QSELIDKIGHDHIHLTTHTAMLALGCQD

Sequences:

>Translated_588_residues
MTPVSAHRPDVQAALLAMIYRYLPFLNWLRHYRREHLPSDVVAGIVTAIMLIPQSMAYAQLAGLPPQIGLYASVAPLIVY
ALLGTSGQLSVGPVAITSLLVFSGVSSLAEPGSARYIQLVLLLAFMVGAIKLTFGVLRLGAILNFISHPVLTAFTSASAL
IIAVGQLKYILGYRIGGEHIHETIGQAIAGLSQTNLVTLTIGLVSIGLLVFFRQGLRPLLRRTGLPPLAITLIVSGAPLL
TVILGILVAQTLFLDQTAGIAVVGAIPAGLSPISVPAFSMADAQALLPTALTIVLVSVVESIAVAKALASKRRQAIDPDQ
ELVALGAANITASFFSGYPVTGGFARSVVNAQAGAITGLASLITALGIAVILLFFTPVFYYLPQAVLAATVIVAVIGLVD
LREPRRIWRTNRGDAFTWLITFLAVLTLGIETGIFVGVASALILYLWRTSRPHIAIVGRLGDSEVYRNVERYQVKTWPHV
VAVRVDESLYFANTRYLESALLQIVAERPSVKHLVLIGSAINFIDSSALHTLEHLIDELRDAGVEFHLADIKGPVMDRLK
QSELIDKIGHDHIHLTTHTAMLALGCQD
>Mature_587_residues
TPVSAHRPDVQAALLAMIYRYLPFLNWLRHYRREHLPSDVVAGIVTAIMLIPQSMAYAQLAGLPPQIGLYASVAPLIVYA
LLGTSGQLSVGPVAITSLLVFSGVSSLAEPGSARYIQLVLLLAFMVGAIKLTFGVLRLGAILNFISHPVLTAFTSASALI
IAVGQLKYILGYRIGGEHIHETIGQAIAGLSQTNLVTLTIGLVSIGLLVFFRQGLRPLLRRTGLPPLAITLIVSGAPLLT
VILGILVAQTLFLDQTAGIAVVGAIPAGLSPISVPAFSMADAQALLPTALTIVLVSVVESIAVAKALASKRRQAIDPDQE
LVALGAANITASFFSGYPVTGGFARSVVNAQAGAITGLASLITALGIAVILLFFTPVFYYLPQAVLAATVIVAVIGLVDL
REPRRIWRTNRGDAFTWLITFLAVLTLGIETGIFVGVASALILYLWRTSRPHIAIVGRLGDSEVYRNVERYQVKTWPHVV
AVRVDESLYFANTRYLESALLQIVAERPSVKHLVLIGSAINFIDSSALHTLEHLIDELRDAGVEFHLADIKGPVMDRLKQ
SELIDKIGHDHIHLTTHTAMLALGCQD

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI262206105, Length=575, Percent_Identity=32.3478260869565, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI262206075, Length=575, Percent_Identity=32.3478260869565, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI262206069, Length=575, Percent_Identity=32.3478260869565, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI262206063, Length=575, Percent_Identity=32.3478260869565, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI45827800, Length=519, Percent_Identity=30.2504816955684, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI39752683, Length=519, Percent_Identity=30.2504816955684, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI94721259, Length=510, Percent_Identity=32.7450980392157, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI94721255, Length=510, Percent_Identity=32.7450980392157, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI94721257, Length=510, Percent_Identity=32.7450980392157, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI94721253, Length=510, Percent_Identity=32.7450980392157, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI269784651, Length=518, Percent_Identity=28.1853281853282, Blast_Score=206, Evalue=7e-53,
Organism=Homo sapiens, GI45827802, Length=467, Percent_Identity=30.8351177730193, Blast_Score=203, Evalue=4e-52,
Organism=Homo sapiens, GI100913030, Length=639, Percent_Identity=25.6651017214397, Blast_Score=192, Evalue=9e-49,
Organism=Homo sapiens, GI47131207, Length=650, Percent_Identity=26.7692307692308, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI20336272, Length=650, Percent_Identity=26.7692307692308, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI4557535, Length=517, Percent_Identity=27.852998065764, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI4505697, Length=500, Percent_Identity=29.2, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI20336282, Length=539, Percent_Identity=24.860853432282, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI16306483, Length=539, Percent_Identity=24.860853432282, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI16418413, Length=524, Percent_Identity=25.763358778626, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI217272867, Length=524, Percent_Identity=25.763358778626, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI16418457, Length=524, Percent_Identity=27.2900763358779, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI301601599, Length=524, Percent_Identity=27.2900763358779, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI65506789, Length=575, Percent_Identity=27.6521739130435, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI45827804, Length=277, Percent_Identity=28.158844765343, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI301601602, Length=206, Percent_Identity=29.6116504854369, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI20336274, Length=86, Percent_Identity=45.3488372093023, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI87081859, Length=554, Percent_Identity=25.812274368231, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI86564196, Length=624, Percent_Identity=24.0384615384615, Blast_Score=209, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17566848, Length=575, Percent_Identity=27.8260869565217, Blast_Score=205, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17551690, Length=601, Percent_Identity=24.2928452579035, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI86565215, Length=564, Percent_Identity=27.4822695035461, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17562578, Length=655, Percent_Identity=25.4961832061069, Blast_Score=194, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI86564876, Length=415, Percent_Identity=28.6746987951807, Blast_Score=151, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI193203292, Length=527, Percent_Identity=23.9089184060721, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI86565213, Length=270, Percent_Identity=28.5185185185185, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI86565209, Length=248, Percent_Identity=28.6290322580645, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI86565211, Length=262, Percent_Identity=27.8625954198473, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323121, Length=472, Percent_Identity=29.2372881355932, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319771, Length=470, Percent_Identity=26.5957446808511, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6325260, Length=589, Percent_Identity=26.3157894736842, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24651449, Length=550, Percent_Identity=29.4545454545455, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI85815873, Length=544, Percent_Identity=31.25, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI21355087, Length=468, Percent_Identity=31.8376068376068, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24647160, Length=468, Percent_Identity=31.8376068376068, Blast_Score=221, Evalue=9e-58,
Organism=Drosophila melanogaster, GI24649801, Length=470, Percent_Identity=31.7021276595745, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI19922482, Length=520, Percent_Identity=29.6153846153846, Blast_Score=213, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24663084, Length=577, Percent_Identity=29.9826689774697, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI21357695, Length=577, Percent_Identity=29.9826689774697, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24666186, Length=554, Percent_Identity=28.3393501805054, Blast_Score=196, Evalue=6e-50,
Organism=Drosophila melanogaster, GI21358229, Length=465, Percent_Identity=32.258064516129, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21358633, Length=545, Percent_Identity=26.605504587156, Blast_Score=188, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 62933; Mature: 62802

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCC
>Mature Secondary Structure 
TPVSAHRPDVQAALLAMIYRYLPFLNWLRHYRREHLPSDVVAGIVTAIMLIPQSMAYAQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LAGLPPQIGLYASVAPLIVYALLGTSGQLSVGPVAITSLLVFSGVSSLAEPGSARYIQLV
HHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LLLAFMVGAIKLTFGVLRLGAILNFISHPVLTAFTSASALIIAVGQLKYILGYRIGGEHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHH
HETIGQAIAGLSQTNLVTLTIGLVSIGLLVFFRQGLRPLLRRTGLPPLAITLIVSGAPLL
HHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHH
TVILGILVAQTLFLDQTAGIAVVGAIPAGLSPISVPAFSMADAQALLPTALTIVLVSVVE
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SIAVAKALASKRRQAIDPDQELVALGAANITASFFSGYPVTGGFARSVVNAQAGAITGLA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
SLITALGIAVILLFFTPVFYYLPQAVLAATVIVAVIGLVDLREPRRIWRTNRGDAFTWLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHH
TFLAVLTLGIETGIFVGVASALILYLWRTSRPHIAIVGRLGDSEVYRNVERYQVKTWPHV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHEEECCCEE
VAVRVDESLYFANTRYLESALLQIVAERPSVKHLVLIGSAINFIDSSALHTLEHLIDELR
EEEEECCCEEEHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
DAGVEFHLADIKGPVMDRLKQSELIDKIGHDHIHLTTHTAMLALGCQD
HCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]