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The map label for this gene is kcsA [H]

Identifier: 222523530

GI number: 222523530

Start: 281801

End: 282529

Strand: Direct

Name: kcsA [H]

Synonym: Chy400_0236

Alternate gene names: 222523530

Gene position: 281801-282529 (Clockwise)

Preceding gene: 222523526

Following gene: 222523532

Centisome position: 5.35

GC content: 54.05

Gene sequence:

>729_bases
ATGTCATCGGAACAACGTGCCACCCTCTTGCATCGATTCGAGCGGATCAGCGAACTGCCGATGCTCTTGCTGTCATTTGG
CTTCCTGATCATCTTCCTCCTGGTTGAGAGCAACGTGTTTGAAGCAACGATCACCCTGGTTCTTGATGGACTGCTCTGGC
TCATTTGGGGGATATTCCTGGCTGAACTGGTGGCAAAACTCTACCTGGCACCTGATCGTCTACACTATCTACGCTCACAT
TGGTTTGAAGTCATCATCATCGTCTTACCGTTCCTTCGCCCCCTGCGTCTGCTGTGGCTACCCATCGTGCTCGCTCGTCT
CTGGAAGCAATCGCAGCGTGCTCTACGCCGCAAGATGCCGGCATTTATCGGGGTAAGTAGCCTGGTTATGGTATTGATTA
CCGCGACCCTGATGTTCATCGCCGAGCGGGGTTCCGGTGGCCCGATCACATCATTCGCCGATGCCATCTGGTGGGCACTG
GCCACCATCACAACGGTCGGCTATGGGGACACCTATCCGGTGACCGCATTGGGACGGGGAATTGCCACATTTCTGATGAT
CGCGGGGATTGCTCTCTTCGGGCTACTAACAGCTAACGTAGCGGCCTTCTTTGTTGAAGAAGATACGGTTGATCGCAGTC
AGGCCGATCTAGCAATGATTAACGAGCGTCTTGCCCGGATTGAGCAATTGTTGGCGGAGATAGTTCAGCGAGAGGCACGT
GAGCGATAA

Upstream 100 bases:

>100_bases
GTAGTAAAACCCAATGATTGACCGGCTGCACCACTTCTGAACATGAGCCAAGTTGTTTATCGTTACAGTATCTCCATCAT
TGATTACCAAGGAGGTGACA

Downstream 100 bases:

>100_bases
CAGTATGGCGGGGCTGGCGCGACTCGAACGCGCAACCATCGACTTAGAAGGTCGGTGCTCTATCCATTGAGCTACAGCCC
CGTATGCCCATACTATACTG

Product: Ion transport 2 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSSEQRATLLHRFERISELPMLLLSFGFLIIFLLVESNVFEATITLVLDGLLWLIWGIFLAELVAKLYLAPDRLHYLRSH
WFEVIIIVLPFLRPLRLLWLPIVLARLWKQSQRALRRKMPAFIGVSSLVMVLITATLMFIAERGSGGPITSFADAIWWAL
ATITTVGYGDTYPVTALGRGIATFLMIAGIALFGLLTANVAAFFVEEDTVDRSQADLAMINERLARIEQLLAEIVQREAR
ER

Sequences:

>Translated_242_residues
MSSEQRATLLHRFERISELPMLLLSFGFLIIFLLVESNVFEATITLVLDGLLWLIWGIFLAELVAKLYLAPDRLHYLRSH
WFEVIIIVLPFLRPLRLLWLPIVLARLWKQSQRALRRKMPAFIGVSSLVMVLITATLMFIAERGSGGPITSFADAIWWAL
ATITTVGYGDTYPVTALGRGIATFLMIAGIALFGLLTANVAAFFVEEDTVDRSQADLAMINERLARIEQLLAEIVQREAR
ER
>Mature_241_residues
SSEQRATLLHRFERISELPMLLLSFGFLIIFLLVESNVFEATITLVLDGLLWLIWGIFLAELVAKLYLAPDRLHYLRSHW
FEVIIIVLPFLRPLRLLWLPIVLARLWKQSQRALRRKMPAFIGVSSLVMVLITATLMFIAERGSGGPITSFADAIWWALA
TITTVGYGDTYPVTALGRGIATFLMIAGIALFGLLTANVAAFFVEEDTVDRSQADLAMINERLARIEQLLAEIVQREARE
R

Specific function: Acts as a potassium ion channel [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the potassium channel family [H]

Homologues:

Organism=Homo sapiens, GI26051262, Length=74, Percent_Identity=39.1891891891892, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI26051260, Length=74, Percent_Identity=39.1891891891892, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI26051266, Length=74, Percent_Identity=39.1891891891892, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI26051264, Length=74, Percent_Identity=39.1891891891892, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003091 [H]

Pfam domain/function: PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 27373; Mature: 27242

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEQRATLLHRFERISELPMLLLSFGFLIIFLLVESNVFEATITLVLDGLLWLIWGIFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AELVAKLYLAPDRLHYLRSHWFEVIIIVLPFLRPLRLLWLPIVLARLWKQSQRALRRKMP
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
AFIGVSSLVMVLITATLMFIAERGSGGPITSFADAIWWALATITTVGYGDTYPVTALGRG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IATFLMIAGIALFGLLTANVAAFFVEEDTVDRSQADLAMINERLARIEQLLAEIVQREAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ER
CC
>Mature Secondary Structure 
SSEQRATLLHRFERISELPMLLLSFGFLIIFLLVESNVFEATITLVLDGLLWLIWGIFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AELVAKLYLAPDRLHYLRSHWFEVIIIVLPFLRPLRLLWLPIVLARLWKQSQRALRRKMP
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
AFIGVSSLVMVLITATLMFIAERGSGGPITSFADAIWWALATITTVGYGDTYPVTALGRG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IATFLMIAGIALFGLLTANVAAFFVEEDTVDRSQADLAMINERLARIEQLLAEIVQREAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ER
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]