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The map label for this gene is ciaR [H]

Identifier: 222523523

GI number: 222523523

Start: 275133

End: 275552

Strand: Direct

Name: ciaR [H]

Synonym: Chy400_0229

Alternate gene names: 222523523

Gene position: 275133-275552 (Clockwise)

Preceding gene: 222523521

Following gene: 222523526

Centisome position: 5.22

GC content: 48.33

Gene sequence:

>420_bases
ATGGTTAACACAAATGGTCATCCGGTGCGGATTCTCCTCGTTGAGGATGATAATAATATCGGGCGGATTATTGAACTGGC
AATGCGCAGCATTAATACGCCCTACGAGTTTGAGTCGGTTCTCAGTGCGGAAGAAGCACTCGAACGCTGGGAGGCGCAGC
CATTCGACTTGCTAATCAGCGATTACAATCTGCGGGGCATGAATGGTGTGCGATTAGTCAAGACGTTGCGTGAACGAGGC
TATTATCCGGCAACCCTCATGGTTACCGCCTACGATTCAGCAGAAGTTCGCGAGGCTGTGAAGGAAGCTGCTATTGATAG
CTACATGACCAAGCCCTTCTTTATCGATGAACTGATCGAGAACATTAAGCAACTTCTGCCTGGCAGTAAACAAATGCGAG
AACGGATTATTAACGGTTAG

Upstream 100 bases:

>100_bases
GTGCTAAACTGAATTTAGGAGAAAAGTACTATTGTCACCGGCGCCACCTCTCAACTGACAACCTTTGCAACGGCGCAGGG
TAGGGGTCAGGGGGTGTCTC

Downstream 100 bases:

>100_bases
TTTCCGTCACCAACTACCTGCAACCTCGCAAAAGGCTCAATAGCGCTCATCGGGGCAACCCTGGCGGTTGCCCCGTTACA
TCTCAATCCAGCAGTGCAGG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MVNTNGHPVRILLVEDDNNIGRIIELAMRSINTPYEFESVLSAEEALERWEAQPFDLLISDYNLRGMNGVRLVKTLRERG
YYPATLMVTAYDSAEVREAVKEAAIDSYMTKPFFIDELIENIKQLLPGSKQMRERIING

Sequences:

>Translated_139_residues
MVNTNGHPVRILLVEDDNNIGRIIELAMRSINTPYEFESVLSAEEALERWEAQPFDLLISDYNLRGMNGVRLVKTLRERG
YYPATLMVTAYDSAEVREAVKEAAIDSYMTKPFFIDELIENIKQLLPGSKQMRERIING
>Mature_139_residues
MVNTNGHPVRILLVEDDNNIGRIIELAMRSINTPYEFESVLSAEEALERWEAQPFDLLISDYNLRGMNGVRLVKTLRERG
YYPATLMVTAYDSAEVREAVKEAAIDSYMTKPFFIDELIENIKQLLPGSKQMRERIING

Specific function: Member of the two-component regulatory system CiaH/CiaR. Involved in early steps of competence regulation and in penicillin susceptibility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 15953; Mature: 15953

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNTNGHPVRILLVEDDNNIGRIIELAMRSINTPYEFESVLSAEEALERWEAQPFDLLIS
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEE
DYNLRGMNGVRLVKTLRERGYYPATLMVTAYDSAEVREAVKEAAIDSYMTKPFFIDELIE
CCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
NIKQLLPGSKQMRERIING
HHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MVNTNGHPVRILLVEDDNNIGRIIELAMRSINTPYEFESVLSAEEALERWEAQPFDLLIS
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEE
DYNLRGMNGVRLVKTLRERGYYPATLMVTAYDSAEVREAVKEAAIDSYMTKPFFIDELIE
CCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
NIKQLLPGSKQMRERIING
HHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]