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The map label for this gene is nirC [H]

Identifier: 222095041

GI number: 222095041

Start: 1371284

End: 1372135

Strand: Reverse

Name: nirC [H]

Synonym: BCQ_1381

Alternate gene names: 222095041

Gene position: 1372135-1371284 (Counterclockwise)

Preceding gene: 222095042

Following gene: 222095031

Centisome position: 26.32

GC content: 35.21

Gene sequence:

>852_bases
ATGCTAGAACAAGGATTAGATTATGTTGTCAAACTGGCTAAGAGCAAAAAACAAATGTTAGATACAAACCCGATGCAATA
TTTCATTCGTGCAGCACTTGCGGGTATTTATATCGGTTTTATTATTGTTCTATGCTTTAAATTAGGTAACTTTTTTCACA
TTGCAGATTCACCAGCAACTTATTTAGCTGCTTCTATGTTTTTCGGAATTGCTCTCGTACTTATTATATATGGTGGTGCT
GAATTGTTTACTGGAAACACAATGTACTTCACTGTAGCAACATTAAGAAAAGAAACAACACTATCTGATACACTTCGTAA
CTGGGTTGCTTGTTATGCAGGTAACTTAGCGGGTGCTTTATTCTTTGCCTTACTATTTTACGCAACTGGCATTTTTGAAG
CAATTGATCACGGTCATTTCATGAATAAAGTAGTAGAAGGAAAAATGAATACACCTACAATGCAACTATTCTTTAAAGCA
ATTTTATGCAACTGGCTTGTATGTCTTGCTTGTTTCTTACCTTCTCAAGTTAAAGGTGATACAGCAAAAATTATGATGAT
GATGATGCTCGTTTTCACATTCTTCTTATCTGGTTACGAGCATAGCATCGCAAACTTATCACTGTTTGCTTTATCTTTAA
TTTCACCGCATCCTGAGACAATTTCTTTTGCAGGTGCTATTCATAACTTAATTCCAGTTACAATCGGTAACATTATTGGT
GGGTCTGTATTTGTCGGTATGGTATACCATTACTTAACAAAGAAAGTACCTGACGTGAAACAAGAAGAAACTGAATTAGG
AGCAGCTCAACAAGAAGAAATCATTCCGTTGCAAGCGCATATGAAACATTAA

Upstream 100 bases:

>100_bases
GTGAAACATTGCACAAACTTATTGAAACTATAAAAGAATCCATGTACTTTATTCATATAAGGAGTATTTATAGATGATGT
ACTAAAGGAGCGTATTACTC

Downstream 100 bases:

>100_bases
AAACTCCAAAGTTTTACTTTGGAGTTTTTAGCTCCCCACATATTTAACAACAAGATTAGGATTAATCTCTCCTTCTTCCT
TCCCCTTATTCATTCTCTGT

Product: formate/nitrite transporter family protein

Products: Proton [Cytoplasm]; nitrite [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLEQGLDYVVKLAKSKKQMLDTNPMQYFIRAALAGIYIGFIIVLCFKLGNFFHIADSPATYLAASMFFGIALVLIIYGGA
ELFTGNTMYFTVATLRKETTLSDTLRNWVACYAGNLAGALFFALLFYATGIFEAIDHGHFMNKVVEGKMNTPTMQLFFKA
ILCNWLVCLACFLPSQVKGDTAKIMMMMMLVFTFFLSGYEHSIANLSLFALSLISPHPETISFAGAIHNLIPVTIGNIIG
GSVFVGMVYHYLTKKVPDVKQEETELGAAQQEEIIPLQAHMKH

Sequences:

>Translated_283_residues
MLEQGLDYVVKLAKSKKQMLDTNPMQYFIRAALAGIYIGFIIVLCFKLGNFFHIADSPATYLAASMFFGIALVLIIYGGA
ELFTGNTMYFTVATLRKETTLSDTLRNWVACYAGNLAGALFFALLFYATGIFEAIDHGHFMNKVVEGKMNTPTMQLFFKA
ILCNWLVCLACFLPSQVKGDTAKIMMMMMLVFTFFLSGYEHSIANLSLFALSLISPHPETISFAGAIHNLIPVTIGNIIG
GSVFVGMVYHYLTKKVPDVKQEETELGAAQQEEIIPLQAHMKH
>Mature_283_residues
MLEQGLDYVVKLAKSKKQMLDTNPMQYFIRAALAGIYIGFIIVLCFKLGNFFHIADSPATYLAASMFFGIALVLIIYGGA
ELFTGNTMYFTVATLRKETTLSDTLRNWVACYAGNLAGALFFALLFYATGIFEAIDHGHFMNKVVEGKMNTPTMQLFFKA
ILCNWLVCLACFLPSQVKGDTAKIMMMMMLVFTFFLSGYEHSIANLSLFALSLISPHPETISFAGAIHNLIPVTIGNIIG
GSVFVGMVYHYLTKKVPDVKQEETELGAAQQEEIIPLQAHMKH

Specific function: Potential Nitrite Transporter. [C]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI87082249, Length=270, Percent_Identity=38.1481481481481, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787132, Length=263, Percent_Identity=30.0380228136882, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788837, Length=278, Percent_Identity=30.2158273381295, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321779, Length=259, Percent_Identity=28.957528957529, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 31393; Mature: 31393

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; nitrite [Periplasm] [C]

Specific reaction: Proton [Periplasm] + nitrite [Periplasm] = Proton [Cytoplasm] + nitrite [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2163394; 7934828; 9384377 [H]