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The map label for this gene is mrsK2 [H]

Identifier: 222094842

GI number: 222094842

Start: 1169940

End: 1171682

Strand: Reverse

Name: mrsK2 [H]

Synonym: BCQ_1180

Alternate gene names: 222094842

Gene position: 1171682-1169940 (Counterclockwise)

Preceding gene: 222094843

Following gene: 222094839

Centisome position: 22.47

GC content: 34.08

Gene sequence:

>1743_bases
ATGAACTTTAATAAACGACTTATTATCCAGTTTATCATGCAACACGTATTTGTTTTAGTTACATTACTGATTGCTGTAGT
AGCTGCATTCACGTATTTAATTTTTCTTGTTACGAGTACTTCATACGAACCGAACATTCCAGATGCTGAAAATTTTATGA
TTGCAAGATACATTTCTTCAGAAGATGGCGATATTTCGTTAAAAGCTGAAATAAAAGACTTAATTAAAGAGAAAAATGAT
TGGATTCAAGTTGTAGAGGAAAACGGAAAAGTTCTCTATCAGTTTAATACGCCAAATGACGTACCGACATCTTATACGAA
AACATCTTTATTCTCGTATATACAGAATCACATAGAAAGTCCTTATACATTTACATATTGGGAAATTGAATTAGAAGAAA
AAAACGTACTTGTTATTTACGGCGGTATGTTAAAAAGCAATGTATTACTGAAAACGATACAGAAAGAGCACCCTTCTGTA
TCTACAGATTCATTCGCATTAACAGAAGAAGAAAAACAGTTACTTTCTAAAGAAAAGGCTACTCTTCAAATCTTTAATAG
TGGCGGCGAAGAAGTATTCTCCTATCCAGATGGAAAGAAAAAAACGTTTTCTGTCATACAAGCTGCTCTTAGCGAAAAGG
AACCGTGGAACCATAAAGAAAACACGTCTAGCTTTTACGACACAAATAGCAATCATCTTCTCGTTGTAACTGCCAAAAAT
GAGTACTACTACCCAGATGATGAAATAGACGATGTATTTGCTAAAAAGTTTCTAATCGGATGCGGATTAATCCTTCTTAT
CGTATTTGTTTATTTAGTCATTCTTTCTATTTGGTACGGTAATAAATTTGGAAAACCGTTATTACATGCGATGCGCTGGC
TTAAAAACATAGCTGGTGGAAAGTACGAAGAGCCTGTTAGTAAAAAAGGAAAACCTATCAGGTTCAGGAAATCTGGTAAA
GAAAAATGGTCATTCCGCTTATTTAGTGATGTTACAAATTCACTAGAGCACCTTTCTATTACACTCAAAAAAAATGATGC
AATGAGGCAAGTACTGCAGCAAACACGTGAAGAATGGATTACTGGTCTAACGCACGATTTAAAAACACCACTAAGTTCTA
TATACGGCTACGCATTATTACTAGAATCAAAACAGTATAACTGGACCGATCGTGACATTCAGCAATTTGGCAGCGTTATG
AAAGAGAAATCTCAATATATGACCACACTAATTGATGACTTAAGCTTAACGTATCAATTAAAAAATAATAGTCTTCCTGC
GCAGCATGTAAACATTGAAATGAATCAATTCGTCCAAAAAGTATTATTACAATTCATTAATAATCCGACACTTCAAAATC
AAAATATTGAATTCGTACCAAGCTCAAATAAAATTCAATATTTCATTGAAGAAAAATGGTTCCAGCGTATTATTGAAAAC
TTACTCGTAAACGCTGTAAAACATAATAATGAAACGACTAATGTAATTGTAAAGCTTTCACAAAATGCTACTTCATTTAC
ACTCTCTATTTCAGATAACGGAAAAGGAATGGATGATAAAACGAAAGAGCTTCTATTTGAGCGATATTACAGAGGAACAA
ATACAGAAGAAAGCAACATCGGAACGGGACTTGGCCTCGCTATTACAAAGCAGCTCGTTCATGCTCATAACGGAACGATT
TCTATCGATAGCGAACTAGGAAAAGGAACGACAATTATACTTGTGTTTCCGTTTCGTTCGTAG

Upstream 100 bases:

>100_bases
AAAACTACGTGAAAAAATCGAACAAGACCCAAGTAAACCCGAATATATAAAAACCGTTCGCGGGCTTGGCTATAAGTTCA
TTACAAAGTAGGGTGACGAT

Downstream 100 bases:

>100_bases
AAAAGGCGCTATGTGGCGTCTTTTCTTTTTTGGGAGAGTTTAGCGGTATATGAAATGATATAGACCATCTTTCTGAGTTG
TTTTAGCGATATATGAAATT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDAENFMIARYISSEDGDISLKAEIKDLIKEKND
WIQVVEENGKVLYQFNTPNDVPTSYTKTSLFSYIQNHIESPYTFTYWEIELEEKNVLVIYGGMLKSNVLLKTIQKEHPSV
STDSFALTEEEKQLLSKEKATLQIFNSGGEEVFSYPDGKKKTFSVIQAALSEKEPWNHKENTSSFYDTNSNHLLVVTAKN
EYYYPDDEIDDVFAKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPVSKKGKPIRFRKSGK
EKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVM
KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNIGTGLGLAITKQLVHAHNGTI
SIDSELGKGTTIILVFPFRS

Sequences:

>Translated_580_residues
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDAENFMIARYISSEDGDISLKAEIKDLIKEKND
WIQVVEENGKVLYQFNTPNDVPTSYTKTSLFSYIQNHIESPYTFTYWEIELEEKNVLVIYGGMLKSNVLLKTIQKEHPSV
STDSFALTEEEKQLLSKEKATLQIFNSGGEEVFSYPDGKKKTFSVIQAALSEKEPWNHKENTSSFYDTNSNHLLVVTAKN
EYYYPDDEIDDVFAKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPVSKKGKPIRFRKSGK
EKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVM
KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNIGTGLGLAITKQLVHAHNGTI
SIDSELGKGTTIILVFPFRS
>Mature_580_residues
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDAENFMIARYISSEDGDISLKAEIKDLIKEKND
WIQVVEENGKVLYQFNTPNDVPTSYTKTSLFSYIQNHIESPYTFTYWEIELEEKNVLVIYGGMLKSNVLLKTIQKEHPSV
STDSFALTEEEKQLLSKEKATLQIFNSGGEEVFSYPDGKKKTFSVIQAALSEKEPWNHKENTSSFYDTNSNHLLVVTAKN
EYYYPDDEIDDVFAKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPVSKKGKPIRFRKSGK
EKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVM
KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNIGTGLGLAITKQLVHAHNGTI
SIDSELGKGTTIILVFPFRS

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=25.4032258064516, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=28.2608695652174, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=24.5689655172414, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=24.3027888446215, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788713, Length=255, Percent_Identity=25.0980392156863, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=25.8064516129032, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789808, Length=251, Percent_Identity=24.3027888446215, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786783, Length=330, Percent_Identity=20, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=20.5240174672489, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=23.4126984126984, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=23.0434782608696, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=308, Percent_Identity=22.4025974025974, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66698; Mature: 66698

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDAENFMIARYISS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
EDGDISLKAEIKDLIKEKNDWIQVVEENGKVLYQFNTPNDVPTSYTKTSLFSYIQNHIES
CCCCEEEHHHHHHHHHCCCHHEEHEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
PYTFTYWEIELEEKNVLVIYGGMLKSNVLLKTIQKEHPSVSTDSFALTEEEKQLLSKEKA
CCEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHCCC
TLQIFNSGGEEVFSYPDGKKKTFSVIQAALSEKEPWNHKENTSSFYDTNSNHLLVVTAKN
EEEEECCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECC
EYYYPDDEIDDVFAKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGG
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
KYEEPVSKKGKPIRFRKSGKEKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWI
CCCCCHHCCCCCEEEECCCCCHHHHEEHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHH
TGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVMKEKSQYMTTLIDDLSLTYQL
HHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
KNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
CCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHH
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNI
HHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
GTGLGLAITKQLVHAHNGTISIDSELGKGTTIILVFPFRS
CCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDAENFMIARYISS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
EDGDISLKAEIKDLIKEKNDWIQVVEENGKVLYQFNTPNDVPTSYTKTSLFSYIQNHIES
CCCCEEEHHHHHHHHHCCCHHEEHEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
PYTFTYWEIELEEKNVLVIYGGMLKSNVLLKTIQKEHPSVSTDSFALTEEEKQLLSKEKA
CCEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHCCC
TLQIFNSGGEEVFSYPDGKKKTFSVIQAALSEKEPWNHKENTSSFYDTNSNHLLVVTAKN
EEEEECCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECC
EYYYPDDEIDDVFAKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGG
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
KYEEPVSKKGKPIRFRKSGKEKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWI
CCCCCHHCCCCCEEEECCCCCHHHHEEHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHH
TGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVMKEKSQYMTTLIDDLSLTYQL
HHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
KNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
CCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHH
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNI
HHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
GTGLGLAITKQLVHAHNGTISIDSELGKGTTIILVFPFRS
CCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]