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The map label for this gene is rbsK [H]

Identifier: 222094419

GI number: 222094419

Start: 732508

End: 733404

Strand: Direct

Name: rbsK [H]

Synonym: BCQ_0733

Alternate gene names: 222094419

Gene position: 732508-733404 (Clockwise)

Preceding gene: 222094418

Following gene: 222094420

Centisome position: 14.05

GC content: 41.14

Gene sequence:

>897_bases
ATGCCAAATATTGCAGTAGTAGGTAGTATTTCAATGGACTTAGTGGCCGTTTCAAAAAAACGTCCGAAAGCAGGGGAAAC
AGTAATTGGTGAAGCATTTCATACAATTCCAGGAGGGAAAGGAGCTAACCAGGCGGTTGCTGCAGCTAGATTAGGCGCAA
ATGTAGCGATGGTTGGAGCGGTAGGAGACGATAATTATGGAACTGTAGTTAGAAAAAATTTAGAGAACGAACGCGTTTTT
ATCGACTATGTGGTACCGGTTACAGATGCGGCGACAGGAATTGCTCATATCGTTTTAGCAGAAGAGGATAACAGTATTGT
TGTCGTGCAAGGAGCGAATGCTCTTGTCAATGAGTCGGTTGTAAATCGTTCAAAAGATCTTCTTATAAAAGCTGATATGG
TTGTGCTTCAACTAGAGATTCCGCTTGAAACAGTAAAATATGTATTAGCTATTTGTGAGGAACACAAAATCCCGGTTATG
TTAAACCCAGCGCCAGCACAAGTGTTATCAGAAGATATTTTAGAAAAGGCAACTTATATTACGCCAAATGAACATGAGTG
TCGCATCGTATTAGATGATTTCACATCACCAATTGAAGAGTTACTGGCTAAATATCCAAACAAACTATTGATGACAGAAG
GTTCTAACGGTGTACGTTTCCATAATGGTACGGAGATTGTACATGTTCCTAGCATTGCTGTTGATGTAGTAGATACGACT
GGAGCTGGTGATACATTTAATGGTGCATTAGCAGTTGCGCTTTCTGAAGGAGAAACACTTCAAAAAGCAATTCGTTTTGC
GAATATTGCTGGTGGTCTTTCTGTAACGAAGCTTGGAGCACAAGGCGGTATGCCAACGAGAGATAGAGTACGTGAAGTGC
AGGTGATTGTCGGATGA

Upstream 100 bases:

>100_bases
TTGTTAGAGCAGATGGAAGGAAACGTATTAGAAGAGAAACACTATCGTTTACCGATTGAAATTATAGAACGAAATACAAC
GAAATAAGGAGATGAAATAG

Downstream 100 bases:

>100_bases
AAAAGCACGGCGTATTAAACAGTGAGATTGCAGCAGTGCTTGCTTCACTTGGACATACGGATACGATTGTAATCGCTGAT
TGCGGTTTACCAATTCCTGA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGAVGDDNYGTVVRKNLENERVF
IDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESVVNRSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVM
LNPAPAQVLSEDILEKATYITPNEHECRIVLDDFTSPIEELLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG

Sequences:

>Translated_298_residues
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGAVGDDNYGTVVRKNLENERVF
IDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESVVNRSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVM
LNPAPAQVLSEDILEKATYITPNEHECRIVLDDFTSPIEELLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG
>Mature_297_residues
PNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGAVGDDNYGTVVRKNLENERVFI
DYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESVVNRSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVML
NPAPAQVLSEDILEKATYITPNEHECRIVLDDFTSPIEELLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTTG
AGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=293, Percent_Identity=34.4709897610922, Blast_Score=141, Evalue=8e-34,
Organism=Escherichia coli, GI1790193, Length=296, Percent_Identity=38.8513513513513, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87082343, Length=308, Percent_Identity=29.8701298701299, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789432, Length=291, Percent_Identity=28.8659793814433, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081971, Length=273, Percent_Identity=24.9084249084249, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788491, Length=289, Percent_Identity=23.8754325259516, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=35.6666666666667, Blast_Score=148, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI25147470, Length=321, Percent_Identity=23.98753894081, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=32.2388059701493, Blast_Score=132, Evalue=5e-32,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=33, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583886, Length=304, Percent_Identity=27.9605263157895, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31536; Mature: 31404

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGA
CCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEE
VGDDNYGTVVRKNLENERVFIDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESV
CCCCCCCHHEEECCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VNRSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVMLNPAPAQVLSEDILEKATYI
HCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCC
TPNEHECRIVLDDFTSPIEELLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
CCCCCCEEEEECHHCHHHHHHHHHCCCEEEEECCCCCEEEECCCEEEEECCEEEEEEECC
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHEEEEEEEC
>Mature Secondary Structure 
PNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGA
CCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEE
VGDDNYGTVVRKNLENERVFIDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESV
CCCCCCCHHEEECCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VNRSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVMLNPAPAQVLSEDILEKATYI
HCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCC
TPNEHECRIVLDDFTSPIEELLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
CCCCCCEEEEECHHCHHHHHHHHHCCCEEEEECCCCCEEEECCCEEEEECCEEEEEEECC
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDRVREVQVIVG
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]