Click here to switch to the map view.

The map label for this gene is treB [H]

Identifier: 222094383

GI number: 222094383

Start: 696140

End: 696568

Strand: Direct

Name: treB [H]

Synonym: BCQ_0697

Alternate gene names: 222094383

Gene position: 696140-696568 (Clockwise)

Preceding gene: 222094382

Following gene: 222094384

Centisome position: 13.35

GC content: 37.76

Gene sequence:

>429_bases
ATGGGGAAAGACTATCGTAAAACAGCAGAGGAAGTGTTGCAGTATATTGGCGGGAAAGACAATATTGAACAAGCTGCGCA
CTGTGTAACGAGACTCCGTATCGCTTTAAAGGATGAAAGTAAAATAGATAACGATAAATTGCAGTCTGTTTCATTAGTAA
AGGGAGCGTTTCATAACGCTGGGGTATTTCAAATTGTAATTGGTCCAGGAGATGTGGATCGTGTTTACGCTGAATTGATA
ACGCTTGCAGGTATGAAAGAATCGACTGTAGCTGACGTAAAAGATTCTGGAAATCAGAAGTTAAATCCAGCTCAAAAGTT
TGTAAAAATATTTTCTGATGTATTTATGCCGATATTACCAGCGATCGTAACAGCTGGTTTACTAATGGGTATTAACAATC
TATTAGGCGCAAAAGGACTTATTTTTTGA

Upstream 100 bases:

>100_bases
AAAAACGACAAACTCGTATATACGAGTGTTGACTAACTTATATATACGAGTTAATATGTAATTGTAAACGGTATCAAAAA
AAGAAAAGAGGGACGGGAAT

Downstream 100 bases:

>100_bases
TGGGAAAAATTTATTAGATGTGTATCCGAACTTAGGTGGGCTTTGGGATTTAATTAATATGATGGCGAATACAGCATTCG
TATTCTTACCAGCACTTGTC

Product: protein-n(pi)-phosphohistidine-sugar phosphotransferase (PTS system trehalose-specific iibc component)

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGVFQIVIGPGDVDRVYAELI
TLAGMKESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKGLIF

Sequences:

>Translated_142_residues
MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGVFQIVIGPGDVDRVYAELI
TLAGMKESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKGLIF
>Mature_141_residues
GKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGVFQIVIGPGDVDRVYAELIT
LAGMKESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKGLIF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1264

COG function: function code G; Phosphotransferase system IIB components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=136, Percent_Identity=31.6176470588235, Blast_Score=91, Evalue=3e-20,
Organism=Escherichia coli, GI1788769, Length=133, Percent_Identity=30.8270676691729, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1790159, Length=123, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=8e-13,
Organism=Escherichia coli, GI48994906, Length=144, Percent_Identity=27.0833333333333, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 15390; Mature: 15259

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
GVFQIVIGPGDVDRVYAELITLAGMKESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILP
CEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
AIVTAGLLMGINNLLGAKGLIF
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNA
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
GVFQIVIGPGDVDRVYAELITLAGMKESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILP
CEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
AIVTAGLLMGINNLLGAKGLIF
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9272861; 9384377; 7651129 [H]