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The map label for this gene is fecC [H]

Identifier: 222094367

GI number: 222094367

Start: 678800

End: 679804

Strand: Direct

Name: fecC [H]

Synonym: BCQ_0681

Alternate gene names: 222094367

Gene position: 678800-679804 (Clockwise)

Preceding gene: 222094364

Following gene: 222094368

Centisome position: 13.02

GC content: 36.92

Gene sequence:

>1005_bases
ATGTTATTAAAAACAAATCGAGCAAAATGGATTGGATTATTTGTTGGAATCATTGCAGTCATTACTTGTATTTGGGGAAG
TATTATTTTCGGATATACAAATACGAGTTGGAATTTAGCGTTAGATGCTTTTTTCCATTTTAATGGGTCCAATGAACATA
TTATTATTCAAAATGTGCGTCTACCAAGAGCATTAATTGCAGCGAGTGTTGGTGCTAGTTTAGCCATTGCAGGTTGTCTT
ATGCAAACTTTAACGAAGAATCCACTTGCTTCTCCAGATTTTATTGGATTAAATTCAGGTGCTGCTTTCTTCATAGTTGT
AGCAATTGTTATTTTTTCCGTAACATCACTATCAGCTTTCACGTGGATTGCCTTTTTGGGGGCAGCAGTTGCAGCTGTAC
TTGTATTTGCTTCTAGTTCTTTAGGAAAAGAGGGGACAACGCCTCTTAAATTAACATTAGCGGGGGTCGCAATTAGTGCG
TTATTTTCATCATTAACACAAGGATTACTTGTTTTAAATGAAAAGGCGCTTGAAGAAGTATTATTTTGGCTTGCCGGATC
TGTGCAAGGAAGAAAGTTAGAAATTTTACAATCTGTATTCCCGTATTTATTAATAGGCTGGATTGCATCTATTATGATGG
CAGGGAAAGTAAATACATTAATGATGGGGGAAGACGTTGCAAAGGGACTTGGGCAACGAACAATTTTAATGAAATCATTC
GTGTTACTTATAATTGTCCTGTTATCTGGTGGTTCAGTTGCTGTTGCTGGTCCAATTGGATTTATTGGAATTATTACCCC
GCATTTTTCTAGATTTCTTGTTGGAGTAGATCACAGATGGAGAATACCGTATAGCGGCTTGTTAGGTGCAATACTATTGA
TTTTAGCTGATATAGCAGCAAGATATGTCATTATGCCACAAGAAGTACCAGTAGGAGTTATGACAGCATTTATTGGTGCG
CCGTTCTTTATTTATATTGCACGTAAGAGAGGGCTTAGCAAATGA

Upstream 100 bases:

>100_bases
CCTCGTTGTCAATGAAAATAATTCTCATTTCCGTTGACAATGAGAATTAAGTTGAAATACACTTACAACGTATCATTATA
CATTGAAGGGGAAACGCTGC

Downstream 100 bases:

>100_bases
AGAAGTATATTCCGTTTCGTATAGGAAAAGGCGAGCTCTCGTTTTTAATGTATAAACGAGCTTGTCTCGTCTTATTCAGT
TTACTAGTTGTTTTAATAGG

Product: iron compound ABC transporter permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLLKTNRAKWIGLFVGIIAVITCIWGSIIFGYTNTSWNLALDAFFHFNGSNEHIIIQNVRLPRALIAASVGASLAIAGCL
MQTLTKNPLASPDFIGLNSGAAFFIVVAIVIFSVTSLSAFTWIAFLGAAVAAVLVFASSSLGKEGTTPLKLTLAGVAISA
LFSSLTQGLLVLNEKALEEVLFWLAGSVQGRKLEILQSVFPYLLIGWIASIMMAGKVNTLMMGEDVAKGLGQRTILMKSF
VLLIIVLLSGGSVAVAGPIGFIGIITPHFSRFLVGVDHRWRIPYSGLLGAILLILADIAARYVIMPQEVPVGVMTAFIGA
PFFIYIARKRGLSK

Sequences:

>Translated_334_residues
MLLKTNRAKWIGLFVGIIAVITCIWGSIIFGYTNTSWNLALDAFFHFNGSNEHIIIQNVRLPRALIAASVGASLAIAGCL
MQTLTKNPLASPDFIGLNSGAAFFIVVAIVIFSVTSLSAFTWIAFLGAAVAAVLVFASSSLGKEGTTPLKLTLAGVAISA
LFSSLTQGLLVLNEKALEEVLFWLAGSVQGRKLEILQSVFPYLLIGWIASIMMAGKVNTLMMGEDVAKGLGQRTILMKSF
VLLIIVLLSGGSVAVAGPIGFIGIITPHFSRFLVGVDHRWRIPYSGLLGAILLILADIAARYVIMPQEVPVGVMTAFIGA
PFFIYIARKRGLSK
>Mature_334_residues
MLLKTNRAKWIGLFVGIIAVITCIWGSIIFGYTNTSWNLALDAFFHFNGSNEHIIIQNVRLPRALIAASVGASLAIAGCL
MQTLTKNPLASPDFIGLNSGAAFFIVVAIVIFSVTSLSAFTWIAFLGAAVAAVLVFASSSLGKEGTTPLKLTLAGVAISA
LFSSLTQGLLVLNEKALEEVLFWLAGSVQGRKLEILQSVFPYLLIGWIASIMMAGKVNTLMMGEDVAKGLGQRTILMKSF
VLLIIVLLSGGSVAVAGPIGFIGIITPHFSRFLVGVDHRWRIPYSGLLGAILLILADIAARYVIMPQEVPVGVMTAFIGA
PFFIYIARKRGLSK

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=304, Percent_Identity=40.1315789473684, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1790741, Length=279, Percent_Identity=37.6344086021505, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1790740, Length=309, Percent_Identity=34.3042071197411, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=33.4494773519164, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788004, Length=283, Percent_Identity=33.5689045936396, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786804, Length=284, Percent_Identity=32.3943661971831, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35658; Mature: 35658

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKTNRAKWIGLFVGIIAVITCIWGSIIFGYTNTSWNLALDAFFHFNGSNEHIIIQNVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCCCEEEEECCC
LPRALIAASVGASLAIAGCLMQTLTKNPLASPDFIGLNSGAAFFIVVAIVIFSVTSLSAF
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHH
TWIAFLGAAVAAVLVFASSSLGKEGTTPLKLTLAGVAISALFSSLTQGLLVLNEKALEEV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFWLAGSVQGRKLEILQSVFPYLLIGWIASIMMAGKVNTLMMGEDVAKGLGQRTILMKSF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHCCHHHHHHHHH
VLLIIVLLSGGSVAVAGPIGFIGIITPHFSRFLVGVDHRWRIPYSGLLGAILLILADIAA
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RYVIMPQEVPVGVMTAFIGAPFFIYIARKRGLSK
HEEECCCCCCHHHHHHHHCCHHHEEEEHHCCCCC
>Mature Secondary Structure
MLLKTNRAKWIGLFVGIIAVITCIWGSIIFGYTNTSWNLALDAFFHFNGSNEHIIIQNVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCCCEEEEECCC
LPRALIAASVGASLAIAGCLMQTLTKNPLASPDFIGLNSGAAFFIVVAIVIFSVTSLSAF
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHH
TWIAFLGAAVAAVLVFASSSLGKEGTTPLKLTLAGVAISALFSSLTQGLLVLNEKALEEV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFWLAGSVQGRKLEILQSVFPYLLIGWIASIMMAGKVNTLMMGEDVAKGLGQRTILMKSF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHCCHHHHHHHHH
VLLIIVLLSGGSVAVAGPIGFIGIITPHFSRFLVGVDHRWRIPYSGLLGAILLILADIAA
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RYVIMPQEVPVGVMTAFIGAPFFIYIARKRGLSK
HEEECCCCCCHHHHHHHHCCHHHEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]