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The map label for this gene is adcA [H]

Identifier: 221232874

GI number: 221232874

Start: 2148625

End: 2150130

Strand: Reverse

Name: adcA [H]

Synonym: SPN23F_22010

Alternate gene names: 221232874

Gene position: 2150130-2148625 (Counterclockwise)

Preceding gene: 221232875

Following gene: 221232872

Centisome position: 96.8

GC content: 42.16

Gene sequence:

>1506_bases
GTGAAAAAAATTAGCTTATTACTAGCCAGTCTATGTGCCTTGTTTTTAGTGGCTTGTTCCAATCAAAAACAGGCAGATGG
TAAACTCAATATCGTGACAACCTTTTACCCTGTCTATGAATTTACCAAGCAAGTCGCAGGAGATACGGCTAATGTAGAAC
TCCTAATCGGTGCTGGGACAGAACCTCATGAATACGAACCATCTGCCAAGGCAGTTGCCAAAATCCAAGATGCAGATACC
TTCGTTTATGAAAATGAAAACATGGAAACATGGGTACCTAAATTGCTAGATACCTTGGATAAGAAAAAAGTGAAAACCAT
CAAGGCGACAGGCGATATGTTGCTCTTGCCAGGTGGCGAGGAAGAAGAGGGAGACCATGACCATGGAGAAGAAGGTCATC
ACCATGAGTTTGATCCCCATGTTTGGTTATCACCAGTTCGTGCCATTAAACTAGTAGAGCACATTCGTGACAGCTTGTCA
GCAGATTATCCTGATAAAAAAGAGACCTTTGAGAAGAATGCAGCTGCCTATATCGAAAAATTGCAAGCCTTGGATAAGGC
TTACGCAGAAGGCTTGTCTCAAGCAAAACAAAAGAGCTTTGTGACTCAACACGCAGCCTTTAACTATCTTGCCTTGGACT
ATGGACTCAAACAAGTCGCAATCTCAGGACTTTCTCCAGATGTAGAGCCATCAGCTGCTCGCTTGGCAGAATTGACAGAG
TATGTCAAGAAAAATAAAATCGCCTATATCTATTTTGAAGAAAATGCCTCACAAGCCCTTGCTAACACACTTTCAAAAGA
AGCAGGTGTCAAAACTGATGTCCTCAATCCTTTAGAAAGTCTGACAGAAGAGGACACCAAGGCTGGAGAAAATTACATCT
CTATCATGGAGAAAAACCTCAAGGCTTTGAAACAAACAACAGACCAAGAAGGCCCAGCAATCGAGCCTGAAAAGGCAGAG
GATACCAAGACAGTCCAAAATGGTTACTTCGAGGATGCAGCTGTCAAGGACCGCACCTTGAGTGACTATGCAGGTAACTG
GCAATCAGTTTATCCTTTCCTTGAAGACGGCACGTTTGACCAAGTCTTTGACTACAAGGCTAAGTTGACTGGTAAGATGA
CCCAGGCTGAGTACAAGGCTTACTATACAAAAGGCTATCAGACAGATGTGACTAAGATTAACATTACTGATAATACTATG
GAATTTGTTCAAGGTGGACAAAGCAAGAAATATACTTACAAGTATGTCGGTAAGAAAATTTTGACTTACAAGAAAGGCAA
TCGTGGCGTGCGTTTCCTCTTTGAAGCCACAGATGCTGACGCTGGACAATTCAAGTATGTTCAGTTTAGTGACCACAATG
TTGCCCCAGTTAAGGCAGAACATTTCCATATCTTTTTTGGAGGTACAAGCCAAGAAGCTCTATTTGAAGAAATGGATAAT
TGGCCAACCTACTACCCAGATAACCTATCTGGCCAAGAAATCGCTCAAGAAATGTTGGCGCATTAA

Upstream 100 bases:

>100_bases
CTATGCAGAAACACCTGCAAGTGCAAGTATTACCATTATTTTTGTAACTGTCTTTATACTAATCAGTTTAGTAAGACGTT
TTATCAAATAGGAGACGAAC

Downstream 100 bases:

>100_bases
TGAGAAATCGACTAGTTCATAAGAGCTAGTCGGTTTTTGGGTACTAGATGGCTAACTTCATTATAGACTTTTCAGAACTA
AGGAACTTTAAAAAAATAAA

Product: zinc-binding protein AdcA precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADT
FVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDVEPSAARLAELTE
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAE
DTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTKINITDNTM
EFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNVAPVKAEHFHIFFGGTSQEALFEEMDN
WPTYYPDNLSGQEIAQEMLAH

Sequences:

>Translated_501_residues
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADT
FVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDVEPSAARLAELTE
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAE
DTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTKINITDNTM
EFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNVAPVKAEHFHIFFGGTSQEALFEEMDN
WPTYYPDNLSGQEIAQEMLAH
>Mature_501_residues
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADT
FVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDVEPSAARLAELTE
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAE
DTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTKINITDNTM
EFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNVAPVKAEHFHIFFGGTSQEALFEEMDN
WPTYYPDNLSGQEIAQEMLAH

Specific function: Part of the ATP-driven transport system AdcABC for zinc. Required for transformability [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI1788284, Length=175, Percent_Identity=52.5714285714286, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI87081990, Length=258, Percent_Identity=24.4186046511628, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 56254; Mature: 56254

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGT
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCC
EPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGE
CCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCC
EEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLSADYPDKKETFEKNAAAYIEK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDVEPSAARLAELTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHH
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISIMEKNL
HHHHCCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
KALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFD
HHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCHHHHCCCHHHCCHHHCCCCHH
QVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTKINITDNTMEFVQGGQSKKYTYKYVGKKI
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHCCHH
LTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNVAPVKAEHFHIFFGGTSQEALFEEMDN
EEEECCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEECEEEEEECCCCHHHHHHHHCC
WPTYYPDNLSGQEIAQEMLAH
CCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGT
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCC
EPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGE
CCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCC
EEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLSADYPDKKETFEKNAAAYIEK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDVEPSAARLAELTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHH
YVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISIMEKNL
HHHHCCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
KALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFD
HHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCHHHHCCCHHHCCHHHCCCCHH
QVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTKINITDNTMEFVQGGQSKKYTYKYVGKKI
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCCCCHHHHHCCHH
LTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNVAPVKAEHFHIFFGGTSQEALFEEMDN
EEEECCCCCEEEEEEECCCCCCCEEEEEECCCCCCCEEECEEEEEECCCCHHHHHHHHCC
WPTYYPDNLSGQEIAQEMLAH
CCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]