| Definition | Streptococcus pneumoniae ATCC 700669, complete genome. |
|---|---|
| Accession | NC_011900 |
| Length | 2,221,315 |
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The map label for this gene is mngB [H]
Identifier: 221232852
GI number: 221232852
Start: 2115262
End: 2117907
Strand: Reverse
Name: mngB [H]
Synonym: SPN23F_21760
Alternate gene names: 221232852
Gene position: 2117907-2115262 (Counterclockwise)
Preceding gene: 221232853
Following gene: 221232851
Centisome position: 95.34
GC content: 44.63
Gene sequence:
>2646_bases ATGGAAAATGTTGTTGTACATATTATCTCACATAGTCACTGGGACCGTGAGTGGTACTTGCCTTTTGAAAGCCATCGTAT GCAGTTGGTGGAATTGTTTGACAATCTCTTTGATCTCTTTGAAAATGACCCTGAGTTCAAGAGTTTCCACTTGGATGGAC AAACTATTGTCCTTGATGACTACTTACAAATTCGCCCTGAAAATCGCGACAAGGTCCAACGCTACATTGACGAGGGCAAA CTTAAAATTGGTCCCTTTTACATCTTGCAGGATGACTACTTGATCTCCAGTGAAGCCAATGTCCGCAATACCTTGATTGG TCAACAAGAAGCTGCCAAATGGGGTAAATCAACCCAGATTGGCTACTTTCCAGATACCTTTGGAAATATGGGACAAGCGC CTCAAATTCTTCAAAAATCAGGCATTCACGTGGCGGCCTTTGGTCGTGGTGTGAAGCCGATTGGATTTGACAACCAAGTC CTTGAAGATGAGCAGTTTACATCCCAGTTTTCAGAAATGTACTGGCAGGGTGTGGATGGTAGTCGTGTTTTAGGTATTCT CTTTGCCAACTGGTACAGTAATGGGAATGAAATCCCAGTTGACAAAGATGAGGCCTTGACCTTCTGGAAACAAAAATTGT CAGATGTGCGTGCCTACGCTTCGACCAACCAATGGTTGATGATGAACGGCTGTGACCACCAGCCTGTACAGAAAAATCTG AGCGAAGCCATTCGTGTGGCAAATGAACTCTTCCCGGATGTAATCTTTGTTCATAGTTCTTTTGATGAATATGTTCAAGC TGTAGAAGGTGCGCTTCCTGAACACTTATCAACTGTTACAGGCGAGTTGACCAGTCAGGAAACAGATGGCTGGTACACAC TTGCCAACACTTCTTCATCCCGCATTTACCTAAAACAAGCCTTCCAAGAAAATAGCAACCTCCTAGAGCAAGTGGTAGAA CCCTTGACTATTATCACTGGTGGACACAACCACAAGGACCAGTTGACCTATGCTTGGAAAACACTTTTGCAGAATGCGCC ACATGATAGTATCTGTGGCTGTAGCGTGGACGAAGTTCACCGCGAGATGGAAACGCGTTTTGCCAAGGTCAACCAAGTAG GAAACTTTGTTAAAAGTAATTTGCTCAACGAGTGGAAGGGTAAAATTGCTACGGATAAGGCTCAAAGTGACTATCTCTTT ACTGTCATTAACACAGGCTTGCATGATAAGGTCGATACTGTCAGCACAGTGATTGATGTGGCGACTTGTGATTTCAAGGA ATTGCACCCAACAGAAGGCTACAAAAAGATGGCTGCTCTTATCTTGCCAAGTTACCGTGTGGAGGACTTGGATGGTCGTC CTGTAGAGGTTACAATCGAAGACCTCGGAGCTAATTTTGAATACGATTTACCAAAAGATAAGTTCCGCCAAGCTCGTATT GCTCGACAAGTGCGCGTGACCATTCCAGTTCACCTAGCACCGCTTTCTTGGACAACCTTCCAATTGCTGGAAGGAGAACA AGAACACCGTGAGGGTATTTACCAAAACGGAGTGATTGATACACCATTCGTAACGGTGAGTGTGGATGACAACATCACAG TCTATGATAAGACAACTCACGAAGCCTATGAAGATTTTATCCGCTTCGAAGACCGGGGTGACATCGGAAACGAGTATATC TATTTCCAACCAAAAGGAACAGAGCCAATCTTTGCAGAGCTTAAGGGCCACGAGGTCTTGGAAAACACAGATCGCTATGC TAAAATCTTGCTCAAACATGAATTGACCGTGCCTGTCAGTGCGGATGAAAAGCTAGAAGAAGAGCAACAAGGTATCATCG AGTTTATGAAGCGTGAGGCTGGACGGTCAGAAGAATTGACAAACATTCCTCTGGAAACTGAGTTGATTGTCTTTGTTGAC AATCCACAAATCCGCTTCAAGACTCGCTTTACTAACACTGCCAAGGATCACCGTATCCGTCTCTTGGTCAAGACTCATAA CACGCGTCCAAGCAATGATTCTGAAAGTATCTATGAGGTGGTGACACGACCAAACAAACCAGCTGCTTCATGGGAAAATC CTGAAAATCCTCAACACCAACAAGCTTTTGTCAGTCTGTATGACGATGAAAAAGGGGTGACTGTATCCAACAAGGGATTG AATGAATACGAAATCCTTGGGGATAACACCATTGCCGTGACCATTTTGCGTGCATCAGGTGAGCTAGGTGACTGGGGCTA CTTCCCAACGCCAGAAGCACAATGCTTGCGTGAGTTTGAAGTCGAATTTGCGATTGAATGCCACCAAGCCCAAGAACGCT TCTCAGCCTATCGTCGTGCCAAAGCCTTGCAGACACCGTTTACCAGCCTTCAGCTTGCTAGACAGGAAGGAAGCGTGGTT GCGACTGGTAGCCTCTTGAGCCATTCTGTTCTCAGCATACCGCAAGTTTGTCCAACAGCCTTTAAAGTGGCGGAAAATGA AGAAGGCTATGTCCTCCGTTACTATAATATGAGTCAAGAAAATGTGCGCATATCAGAACATCAACAAACCATTCTTGACT TACTTGAGCGACCATATCCAGTTCATTCAGGACTATTGGCTCCACAAGAGATTCGTACAGAATTCATCAAAAAAGAAGAA ATTTAA
Upstream 100 bases:
>100_bases TATTCGCTAAGGGGCTCGCTTTAGCTCAACCGATTCTTATCAGAATCACAAGTTTACATTTAAAACGTTAAAATTTAAAT TTAGAATGAGGTTTTACTTC
Downstream 100 bases:
>100_bases TTTCAAAAAGTAAACATCAAAAGAAAGGAGGGGCGAAAAAGTAAGAACTAACTGCTGATTCGCCCCTTTTTATGGTAAAA ACAATGACCATTGCAACGAT
Product: glycosyl hydrolase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 881; Mature: 881
Protein sequence:
>881_residues MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDPEFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGK LKIGPFYILQDDYLISSEANVRNTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRAYASTNQWLMMNGCDHQPVQKNL SEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHLSTVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVE PLTIITGGHNHKDQLTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATDKAQSDYLF TVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDLDGRPVEVTIEDLGANFEYDLPKDKFRQARI ARQVRVTIPVHLAPLSWTTFQLLEGEQEHREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYI YFQPKGTEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSEELTNIPLETELIVFVD NPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVTRPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGL NEYEILGDNTIAVTILRASGELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGSVV ATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLERPYPVHSGLLAPQEIRTEFIKKEE I
Sequences:
>Translated_881_residues MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDPEFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGK LKIGPFYILQDDYLISSEANVRNTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRAYASTNQWLMMNGCDHQPVQKNL SEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHLSTVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVE PLTIITGGHNHKDQLTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATDKAQSDYLF TVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDLDGRPVEVTIEDLGANFEYDLPKDKFRQARI ARQVRVTIPVHLAPLSWTTFQLLEGEQEHREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYI YFQPKGTEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSEELTNIPLETELIVFVD NPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVTRPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGL NEYEILGDNTIAVTILRASGELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGSVV ATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLERPYPVHSGLLAPQEIRTEFIKKEE I >Mature_881_residues MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDPEFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGK LKIGPFYILQDDYLISSEANVRNTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRAYASTNQWLMMNGCDHQPVQKNL SEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHLSTVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVE PLTIITGGHNHKDQLTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATDKAQSDYLF TVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDLDGRPVEVTIEDLGANFEYDLPKDKFRQARI ARQVRVTIPVHLAPLSWTTFQLLEGEQEHREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYI YFQPKGTEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSEELTNIPLETELIVFVD NPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVTRPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGL NEYEILGDNTIAVTILRASGELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGSVV ATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLERPYPVHSGLLAPQEIRTEFIKKEE I
Specific function: May hydrolyze mannosyl-D-glycerate to mannose-6- phosphate and glycerate [H]
COG id: COG0383
COG function: function code G; Alpha-mannosidase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the glycosyl hydrolase 38 family [H]
Homologues:
Organism=Homo sapiens, GI46852164, Length=183, Percent_Identity=28.9617486338798, Blast_Score=67, Evalue=9e-11, Organism=Escherichia coli, GI1786952, Length=877, Percent_Identity=26.3397947548461, Blast_Score=264, Evalue=2e-71,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011013 - InterPro: IPR011330 - InterPro: IPR011682 - InterPro: IPR015341 - InterPro: IPR000602 [H]
Pfam domain/function: PF09261 Alpha-mann_mid; PF01074 Glyco_hydro_38; PF07748 Glyco_hydro_38C [H]
EC number: NA
Molecular weight: Translated: 100839; Mature: 100839
Theoretical pI: Translated: 4.67; Mature: 4.67
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDPEFKSFHLDGQTIVLDD CCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEC YLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVRNTLIGQQEAAKWGKSTQI EEEECCCCHHHHHHHHHCCCEEECCEEEEECCEEECCCCCHHHHHCCCHHHHHCCCCCCC GYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQVLEDEQFTSQFSEMYWQGVDG CCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC SRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRAYASTNQWLMMNGCDHQPVQKNL CCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH SEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHLSTVTGELTSQETDGWYTLANTSSS HHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCC RIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQLTYAWKTLLQNAPHDSICGCSVDEVH EEHHHHHHHCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHH REMETRFAKVNQVGNFVKSNLLNEWKGKIATDKAQSDYLFTVINTGLHDKVDTVSTVIDV HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEECCCCCCHHHHHHHHHHH ATCDFKELHPTEGYKKMAALILPSYRVEDLDGRPVEVTIEDLGANFEYDLPKDKFRQARI HCCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH ARQVRVTIPVHLAPLSWTTFQLLEGEQEHREGIYQNGVIDTPFVTVSVDDNITVYDKTTH HHEEEEEEEEEEECCCCHHHHHHCCCHHHHCCHHHCCCCCCCEEEEEECCCEEEEECCHH EAYEDFIRFEDRGDIGNEYIYFQPKGTEPIFAELKGHEVLENTDRYAKILLKHELTVPVS HHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCEEECCC ADEKLEEEQQGIIEFMKREAGRSEELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIR CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEE LLVKTHNTRPSNDSESIYEVVTRPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGL EEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHEEEECCCCCEEECCCC NEYEILGDNTIAVTILRASGELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRA CCEEEECCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHCHHHEEHHHHHHHHHHHHHHH KALQTPFTSLQLARQEGSVVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQE HHHHCCHHHHHHHHCCCCEEEECHHHHHHHHHCHHHCCHHHHCCCCCCCEEEEEECCCCC NVRISEHQQTILDLLERPYPVHSGLLAPQEIRTEFIKKEEI CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC >Mature Secondary Structure MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDPEFKSFHLDGQTIVLDD CCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEC YLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVRNTLIGQQEAAKWGKSTQI EEEECCCCHHHHHHHHHCCCEEECCEEEEECCEEECCCCCHHHHHCCCHHHHHCCCCCCC GYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQVLEDEQFTSQFSEMYWQGVDG CCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC SRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRAYASTNQWLMMNGCDHQPVQKNL CCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH SEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHLSTVTGELTSQETDGWYTLANTSSS HHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCC RIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQLTYAWKTLLQNAPHDSICGCSVDEVH EEHHHHHHHCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHH REMETRFAKVNQVGNFVKSNLLNEWKGKIATDKAQSDYLFTVINTGLHDKVDTVSTVIDV HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEECCCCCCHHHHHHHHHHH ATCDFKELHPTEGYKKMAALILPSYRVEDLDGRPVEVTIEDLGANFEYDLPKDKFRQARI HCCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHH ARQVRVTIPVHLAPLSWTTFQLLEGEQEHREGIYQNGVIDTPFVTVSVDDNITVYDKTTH HHEEEEEEEEEEECCCCHHHHHHCCCHHHHCCHHHCCCCCCCEEEEEECCCEEEEECCHH EAYEDFIRFEDRGDIGNEYIYFQPKGTEPIFAELKGHEVLENTDRYAKILLKHELTVPVS HHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCEEECCC ADEKLEEEQQGIIEFMKREAGRSEELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIR CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEE LLVKTHNTRPSNDSESIYEVVTRPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGL EEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHEEEECCCCCEEECCCC NEYEILGDNTIAVTILRASGELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRA CCEEEECCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHCHHHEEHHHHHHHHHHHHHHH KALQTPFTSLQLARQEGSVVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQE HHHHCCHHHHHHHHCCCCEEEECHHHHHHHHHCHHHCCHHHHCCCCCCCEEEEEECCCCC NVRISEHQQTILDLLERPYPVHSGLLAPQEIRTEFIKKEEI CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11058132 [H]