| Definition | Streptococcus pneumoniae ATCC 700669, complete genome. |
|---|---|
| Accession | NC_011900 |
| Length | 2,221,315 |
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The map label for this gene is pcpA [H]
Identifier: 221232849
GI number: 221232849
Start: 2108466
End: 2110451
Strand: Reverse
Name: pcpA [H]
Synonym: SPN23F_21690
Alternate gene names: 221232849
Gene position: 2110451-2108466 (Counterclockwise)
Preceding gene: 221232850
Following gene: 221232843
Centisome position: 95.01
GC content: 32.48
Gene sequence:
>1986_bases ATGAAAAAAACTACAATATTATCATTAACTACAGCTGCAGTTATTTTAGCAGCATATGTCCCTAATGAACCAATCCTAGC AGATACTCCTAGTTCGGAAGTAATCAAAGAGACTAAAGTTGGAAGTATTATTCAACAAAATAATATCAAATATAAGGTTC TAACTGTAGAAGGTAACATAGGCACTGTTCAAGTGGGTAATGGAGTTACTCCTGTAGAGTTTGAAGCTGGTCAAGATGGA AAACCATTCACGATTCCTACAAAAATCACAGTAGGTGATAAAGTATTTACCGTTACTGAAGTAGCTAGTCAAGCTTTTAG TTATTATCCAGATGAAACAGGTAGAATTGTCTACTATCCTAGCTCTATTACTATCCCATCAAGCATAAAAAAAATACAAA AAAAAGGCTTCCATGGAAGTAAAGCTAAAACTATTATTTTTGACAAAGGTAGTCAGCTGGAGAAAATTGAAGATAGAGCT TTTGATTTTTCTGAATTAGAAGAGATTGAATTGCCTGCATCTCTAGAATATATTGGAACAAGTGCATTTTCTTTTAGTCA AAAATTGAAAAAGCTAACCTTTTCCTCAAGTTCAAAATTAGAATTAATATCACATGAGGCTTTTGCTAATTTATCAAATT TAGAGAAACTAACATTACCAAAATCGGTTAAAACATTAGGAAGTAATCTATTTAGACTCACTACTAGCTTAAAACATGTT GATGTTGAAGAAGGAAATGAATCGTTTGCCTCAGTTGATGGTGTTTTGTTTTCAAAAGATAAAACCCAATTAATTTATTA TCCAAGTCAAAAAAATGACGAAAGTTATAAAACGCCTAAGGAGACAAAAGAACTTGCATCATATTCGTTTAATAAAAATT CTTACTTGAAAAAACTCGAATTGAATGAAGGTTTAGAAAAAATTGGTACTTTTGCATTTGCAGATGCGATTAAACTTGAA GAAATTAGCTTACCAAATAGTTTAGAAACTATTGAACGTTTAGCCTTTTACGGTAATTTAGAATTAAAAGAACTTATATT ACCAGATAATGTTAAAAATTTTGGTAAACACGTTATGAACGGTTTACCAAAATTAAAAAGTTTAACAATTGGTAATAATA TCAACTCATTGCCGTCCTTCTTCCTAAGTGGCGTCTTAGATTCATTAAAGGAAATTCATATTAAGAATAAAAGTACAGAG TTTTCTGTGAAAAAAGATACATTTGCAATTCCTGAAACTGTTAAGTTCTATGTAACATCAGAACATATAAAAGATGTTCT TAAATCAAATTTATCTACTAGTAATGATATCATTGTTGAAAAAGTAGATAATATAAAACAAGAAACTGATGTAGCTAAAC CTAAAAAGAATTCTAATCAGGGAGTAGTTGGTTGGGTTAAAGACAAAGGTTTATGGTATTACTTAAACGAATCAGGTTCA ATGGCTACTGGTTGGGTTAAAGACAAAGGTTTATGGTATTACTTAAACGAATCAGGTTCAATGGCTACTGGTTGGGTTAA AGACAAAGGCTTATGGTATTACTTAAACGAATCAGGTTCAATGGCTACTGGTTGGGTTAAAGACAAAGGCTTATGGTATT ACTTAAATGAATCAGGTTCAATGGCTACTGGTTGGGTTAAAGACAAAGGCTTATGGTATTACTTAAACGAATCAGGTTCA ATGGCTACTGGTTGGGTTAAAGACAAAGGCTTATGGTATTACTTAAACGAATCAGGTTCAATGGCTACTGGTTGGGTTAA AGACAAAGGCTTATGGTATTACTTAAACGAATCAGGTTCAATGGCTACTGGTTGGGTTAAAGACAAAGGCTTATGGTATT ACTTAAACGAATCAGGTTCAATGGCTACTGGTTGGTTTACAGTTTCTGGTAAATGGTACTATACCTATAATTCAGGAGAT TTATTAGTAAACACGACTACACCCGATGGCTATCGAGTCAATGCTAACGGTGAGTGGGTAGGATAG
Upstream 100 bases:
>100_bases CTATTCTACTAGATAATGATTGAATAAAACTTTTTATAACAACGGCTAGCAAAGTTATAATTTTATATCTATTAGAAAAT AAATATGTAAGGAAATTTAA
Downstream 100 bases:
>100_bases GTATCCATTAGCTAAATCTAATCATTCTGAACTAAAAAATCTGGCTCTTTGTCAACTGTAGTGGGTTGAAAAAAAGCTAA GCTCGAGAAAGGACAAATTT
Product: cell surface choline binding protein PcpA
Products: NA
Alternate protein names: Murein hydrolase [H]
Number of amino acids: Translated: 661; Mature: 661
Protein sequence:
>661_residues MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSIIQQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDG KPFTIPTKITVGDKVFTVTEVASQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLPKSVKTLGSNLFRLTTSLKHV DVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLE EISLPNSLETIERLAFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHIKNKSTE FSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETDVAKPKKNSNQGVVGWVKDKGLWYYLNESGS MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGS MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGD LLVNTTTPDGYRVNANGEWVG
Sequences:
>Translated_661_residues MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSIIQQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDG KPFTIPTKITVGDKVFTVTEVASQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLPKSVKTLGSNLFRLTTSLKHV DVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLE EISLPNSLETIERLAFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHIKNKSTE FSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETDVAKPKKNSNQGVVGWVKDKGLWYYLNESGS MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGS MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGD LLVNTTTPDGYRVNANGEWVG >Mature_661_residues MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSIIQQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDG KPFTIPTKITVGDKVFTVTEVASQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLPKSVKTLGSNLFRLTTSLKHV DVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLE EISLPNSLETIERLAFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHIKNKSTE FSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETDVAKPKKNSNQGVVGWVKDKGLWYYLNESGS MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGS MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGD LLVNTTTPDGYRVNANGEWVG
Specific function: Plays an important role in cell wall degradation and cell separation [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Secreted [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 15 cell wall-binding repeats [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018337 - InterPro: IPR013338 - InterPro: IPR002901 [H]
Pfam domain/function: PF01473 CW_binding_1; PF01832 Glucosaminidase [H]
EC number: =3.2.1.96 [H]
Molecular weight: Translated: 73861; Mature: 73861
Theoretical pI: Translated: 7.18; Mature: 7.18
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSIIQQNNIKYKVLTVEGNI CCCEEEEEHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCCEECCCCEEEEEEEECCE GTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVASQAFSYYPDETGRIVYYP EEEEECCCCCCEEEECCCCCCCEEEEEEEEECCEEEEHHHHHHHHHHCCCCCCCEEEEEC SSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRAFDFSELEEIELPASLEYIGT CCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHCCCCCCCHHHCC SAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLPKSVKTLGSNLFRLTTSLKHV CHHHHHHHHHHHHCCCCCCEEEEHHHHHHCHHCCHHHCCCHHHHHHHHHHEEEEHHHEEE DVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKTPKETKELASYSFNKNSYLKKLE ECCCCCCCHHHCCCEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEH LNEGLEKIGTFAFADAIKLEEISLPNSLETIERLAFYGNLELKELILPDNVKNFGKHVMN HHHHHHHHCCHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH GLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHIKNKSTEFSVKKDTFAIPETVKFYVTS CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCEEEEEEEH EHIKDVLKSNLSTSNDIIVEKVDNIKQETDVAKPKKNSNQGVVGWVKDKGLWYYLNESGS HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEECCCCC MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGS EEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEECCCCC MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGS EEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEECCCCC MATGWVKDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV EEEEEEECCCEEEEECCCCCEEEEEEEECCEEEEEECCCCEEEECCCCCCEEECCCCCCC G C >Mature Secondary Structure MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSIIQQNNIKYKVLTVEGNI CCCEEEEEHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCCEECCCCEEEEEEEECCE GTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVASQAFSYYPDETGRIVYYP EEEEECCCCCCEEEECCCCCCCEEEEEEEEECCEEEEHHHHHHHHHHCCCCCCCEEEEEC SSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRAFDFSELEEIELPASLEYIGT CCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHCCCCCCCHHHCC SAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLPKSVKTLGSNLFRLTTSLKHV CHHHHHHHHHHHHCCCCCCEEEEHHHHHHCHHCCHHHCCCHHHHHHHHHHEEEEHHHEEE DVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKTPKETKELASYSFNKNSYLKKLE ECCCCCCCHHHCCCEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEH LNEGLEKIGTFAFADAIKLEEISLPNSLETIERLAFYGNLELKELILPDNVKNFGKHVMN HHHHHHHHCCHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH GLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHIKNKSTEFSVKKDTFAIPETVKFYVTS CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCEEEEEEEH EHIKDVLKSNLSTSNDIIVEKVDNIKQETDVAKPKKNSNQGVVGWVKDKGLWYYLNESGS HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEECCCCC MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGS EEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEECCCCC MATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGS EEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEECCCCC MATGWVKDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV EEEEEEECCCEEEEECCCCCEEEEEEEECCEEEEEECCCCEEEECCCCCCEEECCCCCCC G C
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10096093; 11544234 [H]