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The map label for this gene is dapH

Identifier: 221232805

GI number: 221232805

Start: 2060687

End: 2061385

Strand: Reverse

Name: dapH

Synonym: SPN23F_21210

Alternate gene names: 221232805

Gene position: 2061385-2060687 (Counterclockwise)

Preceding gene: 221232806

Following gene: 221232804

Centisome position: 92.8

GC content: 46.64

Gene sequence:

>699_bases
ATGACTGCTACAAAAATGAACGCTCAAGAAATTATCCAATTTATCGCCAATGCTGAAAAGAAAACCAGTGTCAAAGTAAC
CTTTGAGGGGCAACTCGCAACTGCTGTGCCTAGCTCTGTTGTCAAACTAGGAAATGTCCTATTCGGAGACTGGAAGGACG
TGGCTCCGCTTCTTGAAGGTTTGGTAGAAAATCAAGATTATGTTGTCGAGCAAGATGCTCGTAATTCTGCAGTTCCTTTG
CTAGATAAGCGTGCTATCAACGCTCGTATCGAGCCAGGTGCTATTATCCGTGACCAGGTGGAAATTGGTGACAATGCTGT
TATCATGATGGGAGCTGTTATCAATATCGGTGCTGAAATCGGTGCTGGAACCATGATTGACATGGGTGCCATCCTTGGTG
GCCGTGCCATCGTTGGAAAAAATAGCCACGTTGGTGCAGGTGCAGTTTTGGCAGGTGTGATTGAGCCAGCTAGTGCTGAA
CCAGTCCGTGTCGGAGACAATGTTCTCATCGGGGCTAATGCAGTGGTTATCGAAGGAGTCCAAATCGGTAGTGGTTCAGT
TGTCGCAGCAGGAGCTATTGTTACCCAAGATGTCCCAGAAAACGTGGTAGTAGCAGGTGTTCCAGCTCGTATTATCAAAG
AAATTGATGCCCAAACTCAACAAAAAACAGCGCTAGAGGATGCGCTTCGTACCTTGTAA

Upstream 100 bases:

>100_bases
ACATCCCTAAAAAATCATACCTAAAAACAGACAAAAAGGTTTCAAATTTGAGGCCTTTTTTGGTAGAATAGGTATCATTA
TAACGAACCAGGAGGCACCT

Downstream 100 bases:

>100_bases
TTGTAAAAGTAAAAAAGAGGCGGAACCCTTTTTCCAGCCTCTTTCTGCTATATCGGAGGACAGATAGATGTTAGATTTGA
TTCAGACTAGACGAGATTTA

Product: transferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLGNVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPL
LDKRAINARIEPGAIIRDQVEIGDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQTQQKTALEDALRTL

Sequences:

>Translated_232_residues
MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLGNVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPL
LDKRAINARIEPGAIIRDQVEIGDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQTQQKTALEDALRTL
>Mature_231_residues
TATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLGNVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLL
DKRAINARIEPGAIIRDQVEIGDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAEP
VRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQTQQKTALEDALRTL

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=171, Percent_Identity=33.9181286549708, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786537, Length=136, Percent_Identity=32.3529411764706, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786664, Length=56, Percent_Identity=60.7142857142857, Blast_Score=68, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322243, Length=134, Percent_Identity=32.089552238806, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_STRP2 (Q04I77)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817311.1
- ProteinModelPortal:   Q04I77
- SMR:   Q04I77
- STRING:   Q04I77
- EnsemblBacteria:   EBSTRT00000019952
- GeneID:   4443052
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1923
- eggNOG:   COG2171
- GeneTree:   EBGT00050000026810
- HOGENOM:   HBG704071
- OMA:   KNAVIMM
- ProtClustDB:   CLSK876718
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 23920; Mature: 23789

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLGNVLFGDWKDVAPLLEG
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEIGDNAVIMMGAVINIGAEI
HHCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHCCCCC
GAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAEPVRVGDNVLIGANAVVIEGV
CCCCEEHHHHHHCCEEEECCCCCCCCHHHHHHHCCCCCCCCEEECCEEEEECCEEEEEEE
QIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQTQQKTALEDALRTL
EECCCCEEEECEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLGNVLFGDWKDVAPLLEG
CCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEIGDNAVIMMGAVINIGAEI
HHCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHCCCCC
GAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAEPVRVGDNVLIGANAVVIEGV
CCCCEEHHHHHHCCEEEECCCCCCCCHHHHHHHCCCCCCCCEEECCEEEEECCEEEEEEE
QIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQTQQKTALEDALRTL
EECCCCEEEECEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA