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The map label for this gene is oxaA1

Identifier: 221232758

GI number: 221232758

Start: 2004060

End: 2004890

Strand: Reverse

Name: oxaA1

Synonym: SPN23F_20630

Alternate gene names: 221232758

Gene position: 2004890-2004060 (Counterclockwise)

Preceding gene: 221232759

Following gene: 221232757

Centisome position: 90.26

GC content: 41.52

Gene sequence:

>831_bases
ATGGGAGTGAAAAAGAAACTAAAGTTGACTAGTTTGCTAGGACTGTCTCTGTTAATCATGACAGCCTGTGCGACTAATGG
GGTAACTAGCGATATTACAGCCGAATCGGCTGATTTTTGGAGTAAATTGGTTTACTTCTTTGCGGAAATCATTCGCTTTT
TATCGTTTGATATTAGTATCGGAGTGGGGATTATTCTCTTTACGGTCTTGATTCGTACAGTCCTCTTGCCAGTCTTTCAG
GTGCAAATGGTGGCTTCTAGGAAAATGCAGGAAGCTCAGCCACGCATTAAGGCGCTTCGAGAACAATATCCAGGTCGAGA
TATGGAAAGCAGAACCAAACTAGAGCAGGAAATGCGTAAAGTATTTAAAGAAATGGGTGTCAGACAGTCAGACTCTCTTT
GGCCGATTTTGATTCAGATGCCGGTTATTTTGGCCCTGTTCCAAGCCCTATCAAGAGTTGACTTTTTAAAGACAGGTCAT
TTCTTATGGATTAACCTTGGTAGTGTGGATACAACCCTTGTTCTTCCGATTTTAGCAGCAGTATTCACCTTTTTAAGTAC
TTGGTTGTCCAACAAAGCTTTGTCTGAGCGAAATGGCGCTACGACTGCGATGATGTATGGGATTCCAGTCTTGATTTTTA
TCTTTGCAGTTTATGCGCCAGGTGGAGTCGCCCTATACTGGACAGTGTCTAATGCTTATCAAGTCTTGCAAACCTATTTC
TTGAATAATCCATTCAAGATTATCGCAGAGCGCGAGGCCGTAGTACAGGCACAAAAAGATTTGGAAAATAGAAAAAGAAA
AGCCAAGAAAAAGGCTCAGAAAACGAAATAA

Upstream 100 bases:

>100_bases
GTTGTCATTGCTCGAAAAGGAGTCGAAACCTTGGGATACGCAGAGATGGAGAAAAATCTACTCCATGTATTAAAATTATC
AAAGATTTACCGGGAAGGAA

Downstream 100 bases:

>100_bases
ATAAGGAGGAATCTGGTAATGGTAGTATTTACAGGTTCAACTGTTGAAGAAGCAATCCAGAAAGGATTGAAAGAATTAGA
TATTCCAAGAATGAAGGCTC

Product: membrane protein OxaA 1 precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MGVKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQ
VQMVASRKMQEAQPRIKALREQYPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGH
FLWINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYF
LNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK

Sequences:

>Translated_276_residues
MGVKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQ
VQMVASRKMQEAQPRIKALREQYPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGH
FLWINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYF
LNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK
>Mature_275_residues
GVKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQV
QMVASRKMQEAQPRIKALREQYPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHF
LWINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYFL
NNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=209, Percent_Identity=29.6650717703349, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA1_STRR6 (Q8DN93)

Other databases:

- EMBL:   AE007317
- PIR:   B98103
- RefSeq:   NP_359444.1
- STRING:   Q8DN93
- EnsemblBacteria:   EBSTRT00000015620
- GeneID:   933908
- GenomeReviews:   AE007317_GR
- KEGG:   spr:spr1852
- eggNOG:   COG0706
- GeneTree:   EBGT00050000027293
- HOGENOM:   HBG560622
- OMA:   MKSAPER
- ProtClustDB:   CLSK803899
- BioCyc:   SPNE171101:SPR1852-MONOMER
- HAMAP:   MF_01811
- InterPro:   IPR001708
- InterPro:   IPR023060
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 31213; Mature: 31082

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x105c3cd8)-; HASH(0x145fcd00)-; HASH(0x1441be40)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYPGRDMESRTKLEQEMRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFLWINLGSVDTTLVLPILAA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
VFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHH
LNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
GVKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYPGRDMESRTKLEQEMRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
VFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFLWINLGSVDTTLVLPILAA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
VFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHH
LNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11544234