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The map label for this gene is yfbQ [C]

Identifier: 221232718

GI number: 221232718

Start: 1954987

End: 1956201

Strand: Reverse

Name: yfbQ [C]

Synonym: SPN23F_20150

Alternate gene names: 221232718

Gene position: 1956201-1954987 (Counterclockwise)

Preceding gene: 221232719

Following gene: 221232717

Centisome position: 88.06

GC content: 44.77

Gene sequence:

>1215_bases
ATGAAAGAATATAACAAGTCTAGTAAGTTAGAGCATGTTGCTTATGATATCCGTGGTCCTGTATTGGAAGAAGCCATGCG
GATGCGAGCGAATGGAGAAAAGATTTTACGTCTGAATACAGGAAATCCAGCAGAATTTGGCTTTACAGCGCCAGACGAGG
TCATTCATGACTTGATTATGAATGCGCGTGATAGTGAAGGCTATTCTGACTCCAAAGGGATTTTCTCAGCCCGTAAGGCC
ATCATGCAGTATTGCCAGCTGAAGAAATTCCCAAACGTAGATATTGATGATATTTACCTTGGAAATGGTGTCAGTGAGTT
GATTGTCATGTCCATGCAGGGGCTTTTGGACAATGGGGATGAGGTCTTAGTGCCAATGCCAGACTATCCTCTATGGACGG
CGGCTGTCAGCCTAGCTGGAGGAAATGCCGTTCACTATATCTGTGATGAAGCTGTTGAATGGTACCCAGATATTGACGAT
ATCAAGTCAAAAATCACTTCCAATACCAAGGCAATCGTCCTTATCAATCCAAATAACCCAACTGGAGCCCTTTATCCTAA
GGAACTCTTGCTGGAGATTATTGAGATTGCCCGTCAAAACGATTTGATTATCTTTGCGGATGAAATCTATGACCGCATGG
TAATGGACGGACATGTGCATACGCCTGTGGCGAGCTTGGCACCAGATGTCTTCTGTGTCAGCATGAATGGTCTGTCAAAA
TCCCACCGCATAGCAGGTTTCCGTGTGGGTTGGATGGTCTTGTCTGGCCCTAAGACTCATGTTAAGGGCTATATCGAAGG
GCTCAATATGCTGTCCAATATGCGCCTTTGCTCTAACGTTTTGGCCCAACAAGTCGTACAAACTTCCTTGGGGGGTCACC
AATCAGTCGATGAATTGCTTCTTCCTGGTGGACGAATCTACGAGCAAAGAAATTTCATCTATAATGCCATTCAAGATATT
CCAGGTTTGTCTGCCGTTAAACCCAAGGCGGGGCTCTATATCTTCCCAAAAATCGACCGCAATATGTACCGTATCGATGA
TGATGAGCAGTTTGTCCTTGATTTCTTGAAGCAGGAAAAGGTTCTCTTGGTTCATGGTCGAGGCTTTAACTGGCAGGAAC
CAGACCACTTCCGTATCGTTTACCTTCCTCGTGTTGATGAGTTAGCCCAAATCCAAGAAAAGATGACTCGTTTCTTGAAA
CAGTATCGTAGATAG

Upstream 100 bases:

>100_bases
GTTTTTCTTCTATACGAAACTAGTAACACATTTCAGTAAACTTGTCGCATTCTCTTTCTAGTGGTATAATGTTACTATCC
TGATGAATTGAGGAAACAAG

Downstream 100 bases:

>100_bases
GGCTTGCATTCGAAAAAGCTGGAAACATTTGCCTAGAGCTATTGACAAAAGTGAAAGAATCAGATAGAATAGTAAAGTAT
GTTTAGTAACTGATCACTTT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKA
IMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDI
PGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLK
QYRR

Sequences:

>Translated_404_residues
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKA
IMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDI
PGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLK
QYRR
>Mature_404_residues
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKA
IMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDI
PGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLK
QYRR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=394, Percent_Identity=26.3959390862944, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=25.2032520325203, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=25.4742547425474, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI4885351, Length=360, Percent_Identity=25, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI95147551, Length=162, Percent_Identity=31.4814814814815, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI169881279, Length=162, Percent_Identity=31.4814814814815, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI56713256, Length=266, Percent_Identity=23.6842105263158, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI56713254, Length=266, Percent_Identity=23.6842105263158, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI169881281, Length=124, Percent_Identity=34.6774193548387, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI149944424, Length=367, Percent_Identity=24.2506811989101, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=62.1287128712871, Blast_Score=545, Evalue=1e-156,
Organism=Escherichia coli, GI1788722, Length=398, Percent_Identity=26.3819095477387, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786816, Length=243, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=28.5340314136126, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=392, Percent_Identity=23.9795918367347, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=171, Percent_Identity=32.1637426900585, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=180, Percent_Identity=32.7777777777778, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=180, Percent_Identity=32.7777777777778, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=160, Percent_Identity=27.5, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323118, Length=377, Percent_Identity=27.3209549071618, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=384, Percent_Identity=26.3020833333333, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=170, Percent_Identity=27.0588235294118, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18859735, Length=399, Percent_Identity=26.5664160401003, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24641770, Length=379, Percent_Identity=27.9683377308707, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641760, Length=379, Percent_Identity=27.9683377308707, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641768, Length=379, Percent_Identity=27.9683377308707, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641766, Length=379, Percent_Identity=27.9683377308707, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641764, Length=379, Percent_Identity=27.9683377308707, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45551451, Length=379, Percent_Identity=27.9683377308707, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28573069, Length=327, Percent_Identity=23.8532110091743, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24646114, Length=327, Percent_Identity=23.8532110091743, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28573067, Length=327, Percent_Identity=23.8532110091743, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28573065, Length=327, Percent_Identity=23.8532110091743, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45742; Mature: 45742

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIM
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCC
EVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDDIKSKITSNTKAIVLINPNNP
EEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCC
TGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLAPDVFCVSMNGLSK
CCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCC
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELL
CCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCC
VLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLKQYRR
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPAEFGFTAPDEVIHDLIM
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGNGVSELIVMSMQGLLDNGD
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCC
EVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDDIKSKITSNTKAIVLINPNNP
EEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCC
TGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGHVHTPVASLAPDVFCVSMNGLSK
CCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCC
SHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRLCSNVLAQQVVQTSLGGHQSVDELL
CCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYIFPKIDRNMYRIDDDEQFVLDFLKQEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCC
VLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQEKMTRFLKQYRR
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]