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The map label for this gene is engC

Identifier: 221232708

GI number: 221232708

Start: 1945372

End: 1946250

Strand: Reverse

Name: engC

Synonym: SPN23F_20040

Alternate gene names: 221232708

Gene position: 1946250-1945372 (Counterclockwise)

Preceding gene: 221232709

Following gene: 221232707

Centisome position: 87.62

GC content: 43.57

Gene sequence:

>879_bases
ATGCAGGGACAAATCATTAAAGCCTTGGCAGGTTTCTACTATGTGGAGAGTGATGGCCAGGTTTATCAAACACGCGCGCG
TGGGAATTTCCGTAAAAAAGGCCATACCCCTTATGTTGGGGACTGGGTAGATTTCTCTGCCGAGGAAAATTCAGAAGGCT
ATATCCTCAAAATTCACGAACGGAAAAACAGTCTGGTTCGTCCGCCTATTGTCAATATCGATCAAGCTGTAGTAATCATG
TCCGTCAAGGAACCTGATTTTAACAGCAATTTGCTGGATCGTTTCTTGGTTCTTTTGGAGCACAAGGGCATCCATCCCAT
TGTCTATATTTCCAAAATGGATTTGTTGGAAGATAGGGGAGAACTGGATTTTTACCAGCAGACCTATGGTGACATCGGCT
ATGACTTTGTGACCAGTAAAGAGGAACTCCTGTCTTTGTTAACAGGCAAGGTTACGGTCTTTATGGGGCAGACAGGTGTT
GGGAAGTCAACTCTTCTCAATAAAATCGCACCAGACCTCAATCTTGAAACGGGAGAAATTTCAGACAGTCTAGGTCGCGG
TCGCCATACCACTCGAGCTGTTAGTTTTTACAATCTCAACGGGGGTAAAATCGCAGATACACCAGGATTTTCATCCTTGG
ACTATGAAGTATCAAGGGCTGAAGACCTCAATCAGGCTTTCCCAGAGATTGCTACTGTTAGCCGAGATTGTAAGTTCCGT
ACTTGTACCCATACCCATGAGCCGTCTTGTGCCGTCAAACCAGCTGTTGAAGAGGGTGTTATTGCAACCTTCCGTTTTGA
CAATTACCTGCAATTCCTTAGTGAAATTGAAAATCGTAGAGAAACCTATAAAAAAGTCAGCAAAAAAATTCCAAAATAA

Upstream 100 bases:

>100_bases
TTGGACCAGGCAGGCTTGTCACCAAGTGTGCGTGGGGAAGCTCTCAGCTTGGCAGAATTTGCCGGTCTAGCAGACGCACT
TAAAGGGCAAGGACTCTAAG

Downstream 100 bases:

>100_bases
GGAGAAACCTATGTCTCAATACAAGATTGCTCCGTCAATTCTGGCAGCAGATTATGCCAACTTTGAACGTGAAATCAAAC
GTCTAGAAGCAACTGGGGCA

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVDFSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIM
SVKEPDFNSNLLDRFLVLLEHKGIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVSRAEDLNQAFPEIATVSRDCKFR
TCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEIENRRETYKKVSKKIPK

Sequences:

>Translated_292_residues
MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVDFSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIM
SVKEPDFNSNLLDRFLVLLEHKGIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVSRAEDLNQAFPEIATVSRDCKFR
TCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEIENRRETYKKVSKKIPK
>Mature_292_residues
MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVDFSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIM
SVKEPDFNSNLLDRFLVLLEHKGIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVSRAEDLNQAFPEIATVSRDCKFR
TCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEIENRRETYKKVSKKIPK

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=311, Percent_Identity=36.6559485530547, Blast_Score=157, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA_STRPN (P67684)

Other databases:

- EMBL:   AE005672
- PIR:   B95232
- RefSeq:   NP_346411.1
- ProteinModelPortal:   P67684
- SMR:   P67684
- EnsemblBacteria:   EBSTRT00000025615
- GeneID:   930526
- GenomeReviews:   AE005672_GR
- KEGG:   spn:SP_1984
- TIGR:   SP_1984
- GeneTree:   EBGT00050000027431
- HOGENOM:   HBG652450
- OMA:   RGDWERY
- ProtClustDB:   PRK00098
- BioCyc:   SPNE170187-1:SP_1984-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004881
- Gene3D:   G3DSA:2.40.50.140
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 32994; Mature: 32994

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVDFSAEENSEGYILKIHE
CCCHHHHHHHCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
RKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHKGIHPIVYISKMDLLEDRG
CCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCC
ELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGVGKSTLLNKIAPDLNLETGEI
CCHHHHHHHCCCCCHHHCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCC
SDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVSRAEDLNQAFPEIATVSRDCKFR
CHHHCCCCCCEEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
TCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEIENRRETYKKVSKKIPK
ECCCCCCCCCCCCCCHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVDFSAEENSEGYILKIHE
CCCHHHHHHHCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
RKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHKGIHPIVYISKMDLLEDRG
CCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCC
ELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGVGKSTLLNKIAPDLNLETGEI
CCHHHHHHHCCCCCHHHCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCC
SDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVSRAEDLNQAFPEIATVSRDCKFR
CHHHCCCCCCEEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
TCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEIENRRETYKKVSKKIPK
ECCCCCCCCCCCCCCHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916