| Definition | Streptococcus pneumoniae ATCC 700669, complete genome. |
|---|---|
| Accession | NC_011900 |
| Length | 2,221,315 |
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The map label for this gene is scrA [H]
Identifier: 221232457
GI number: 221232457
Start: 1664788
End: 1666671
Strand: Reverse
Name: scrA [H]
Synonym: SPN23F_17230
Alternate gene names: 221232457
Gene position: 1666671-1664788 (Counterclockwise)
Preceding gene: 221232460
Following gene: 221232456
Centisome position: 75.03
GC content: 43.95
Gene sequence:
>1884_bases ATGAACAATCAGGAAATTGCAAAAAAAGTCATCGATGCCTTGGGCGGACGTGAAAATGTCAATAGTGTTGCCCACTGTGC GACACGTCTACGTGTCATGGTCAAAGATGAAGAGAAAATCAATAAAGAAGTGATTGAGAACTTGGAAAAAGTTCAAGGTG CTTTCTTTAACTCAGGGCAATACCAAATTATCTTTGGTACAGGTACAGTTAACAAAATGTACGATGAAGTTGTTGTACTT GGATTACCAACATCATCTAAGGATGACATGAAAGCAGAAGTTGCTAAACAAGGGAACTGGTTCCAACGTGCTATCCGTAC TTTTGGTGATGTTTTCGTTCCAATCATCCCAGTTATCGTAGCGACAGGTCTCTTCATGGGTGTGCGTGGTCTTTTCAACG CTCTTGAAATGCCACTTCCAGGTGACTTTGCAACTTACACACAAATCTTGACAGATACAGCCTTCATCATCTTGCCAGGT TTGGTTGTGTGGTCAACCTTCCGTGTATTTGGTGGAAATCCTGCCGTTGGTATCGTTCTTGGTATGATGCTTGTCTCTGG CTCACTTCCAAACGCTTGGGCAGTTGCTCAAGGTGGTGAAGTAACAGCGATGAACTTCTTTGGTTTCATCCCTGTTGTTG GTTTGCAAGGTTCCGTTCTTCCAGCCTTCATCATCGGGGTTGTCGGAGCTAAATTTGAAAAAGCTGTCCGCAAGGTTGTT CCAGATGTCATTGACCTCTTGGTAACACCATTCGTGACACTTTTGGTCATGTCTATCCTTGGACTCTTTGTCATTGGACC AGTTTTCCACGTTGTTGAAAACTACATCCTTATTGCTACAAAAGCGATTCTTAGCATGCCATTTGGTCTTGGTGGTTTCT TGATTGGTGGGGTTCACCAATTGATCGTCGTGTCAGGTGTGCACCACATCTTCAACTTGCTTGAAGTGCAATTACTTGCT GCTGACCATGCTAACCCATTCAACGCTATCATCACAGCTGCTATGACAGCTCAAGGTGCTGCTACTGTTGCGGTTGGTGT TAAAACAAAAAATCCAAAACTGAAAACACTTGCTTTCCCGGCTGCTCTTTCTGCCTTCCTAGGTATTACAGAGCCTGCTA TCTTCGGGGTGAACTTGCGCTTCCGTAAACCATTCTTCCTTTCATTGATTGCTGGTGCAATCGGTGGTGGATTGGCTTCT ATCCTTGGACTTGCTGGTACTGGTAATGGTATCACCATCATCCCTGGTACAATGCTTTATGTTGGTAACGGACAACTTCC ACAATACCTTCTTATGGTAGCTGTATCATTTGCCCTTGGTTTTGCTCTTACTTACATGTTTGGTTACGAAGATGAAGTAG ACGCAACTGCAGCTGCAAAACAAGCTGAAGTGGCTGAAGAAAAAGAAGAAGTTGCGCCAGCAGCTCTTCAAAATGAAACA CTTGTAACTCCTATCGTCGGTGATGTTGTCGCTCTTGCTGATGTCAATGACCCAGTCTTCTCAAGTGGAGCTATGGGACA AGGTATCGCTGTGAAACCAAGCCAAGGCGTGGTCTATGCACCAGCTGATGCTGAAGTTTCAATTGCCTTTCCAACAGGGC ACGCTTTTGGTTTGAAAACAAGAAATGGTGCTGAAGTTTTGATTCATGTTGGTATTGACACTGTATCTATGAACGGTGAC GGTTTTGAAGCAAAAGTTGCTCAAGGTGATAAGGTGAAAGTTGGCGATGTTCTTGGAACATTTGACTCAAATAAAATCGC TACAGCTGGACTTGATGATACAACAATGGTTATCGTTACAAATACAGCTGACTACGCTTCAGTAGCTCCAGTCGCAACAG GTTCAGTTGCGAAGGGGGATGCTGTGATCGAAGTGAAAATCTAA
Upstream 100 bases:
>100_bases CGCTTGACATATTTTTAAAACATGATAAAATAATAGTCGTAAGGGCGAATAAAATCGCTTTCAAACAAGAACAAAATGTT ATATAAGGAGATTTTTGCAA
Downstream 100 bases:
>100_bases TCAATCCTCTCTAATGTGAAAACGAACAAATGACATGTTTGTTCGTTTTTATTAGATAGTAAGATTTACAGAGGAAAATC TAAAAAATAGAGACATTTAG
Product: sucrose-specific phosphotransferase system (PTS), IIABC component
Products: NA
Alternate protein names: EIIBCA-Scr; EII-Scr; Sucrose-specific phosphotransferase enzyme IIB component; PTS system sucrose-specific EIIB component; Sucrose permease IIC component; PTS system sucrose-specific EIIC component; Sucrose-specific phosphotransferase enzyme IIA component; PTS system sucrose-specific EIIA component [H]
Number of amino acids: Translated: 627; Mature: 627
Protein sequence:
>627_residues MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVL GLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLA ADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLAS ILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGD GFEAKVAQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIEVKI
Sequences:
>Translated_627_residues MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVL GLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLA ADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLAS ILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGD GFEAKVAQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIEVKI >Mature_627_residues MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVL GLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLA ADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLAS ILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGD GFEAKVAQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIEVKI
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI1790159, Length=635, Percent_Identity=29.7637795275591, Blast_Score=257, Evalue=1e-69, Organism=Escherichia coli, GI2367362, Length=428, Percent_Identity=29.2056074766355, Blast_Score=215, Evalue=8e-57, Organism=Escherichia coli, GI48994906, Length=506, Percent_Identity=29.8418972332016, Blast_Score=147, Evalue=1e-36, Organism=Escherichia coli, GI1788769, Length=476, Percent_Identity=26.890756302521, Blast_Score=124, Evalue=2e-29, Organism=Escherichia coli, GI1786894, Length=160, Percent_Identity=36.875, Blast_Score=107, Evalue=3e-24, Organism=Escherichia coli, GI1788757, Length=147, Percent_Identity=34.6938775510204, Blast_Score=93, Evalue=4e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011055 - InterPro: IPR018113 - InterPro: IPR001127 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 - InterPro: IPR011535 - InterPro: IPR010973 [H]
Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 65671; Mature: 65671
Theoretical pI: Translated: 4.98; Mature: 4.98
Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQ CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCC YQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIV EEEEEECCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH ATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVVWSTFRVFGGNPAVGIVL HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH GMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV HHHHHCCCCCCCEEEECCCCEEEEEHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH LIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFP HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEHH AALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLASILGLAGTGNGITIIPGTMLY HHHHHHHCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEE VGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCE LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKT EECHHHHCEEEEECCCCCCCCCCCCCCCEEECCCCCEEECCCCCEEEEEECCCCEEECCC RNGAEVLIHVGIDTVSMNGDGFEAKVAQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVT CCCCEEEEEECCEEEEECCCCCEEEECCCCCEEECHHEECCCCCCEEECCCCCCEEEEEE NTADYASVAPVATGSVAKGDAVIEVKI CCCCCCCCCCCCCCCCCCCCEEEEEEC >Mature Secondary Structure MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQ CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCC YQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIV EEEEEECCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH ATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVVWSTFRVFGGNPAVGIVL HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH GMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV HHHHHCCCCCCCEEEECCCCEEEEEHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH LIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFP HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEHH AALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLASILGLAGTGNGITIIPGTMLY HHHHHHHCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEE VGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCE LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKT EECHHHHCEEEEECCCCCCCCCCCCCCCEEECCCCCEEECCCCCEEEEEECCCCEEECCC RNGAEVLIHVGIDTVSMNGDGFEAKVAQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVT CCCCEEEEEECCEEEEECCCCCEEEECCCCCEEECHHEECCCCCCEEECCCCCCEEEEEE NTADYASVAPVATGSVAKGDAVIEVKI CCCCCCCCCCCCCCCCCCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 2536656; 12397186; 8336109 [H]