| Definition | Streptococcus pneumoniae ATCC 700669, complete genome. |
|---|---|
| Accession | NC_011900 |
| Length | 2,221,315 |
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The map label for this gene is nanB [H]
Identifier: 221232423
GI number: 221232423
Start: 1626581
End: 1628674
Strand: Reverse
Name: nanB [H]
Synonym: SPN23F_16870
Alternate gene names: 221232423
Gene position: 1628674-1626581 (Counterclockwise)
Preceding gene: 221232424
Following gene: 221232422
Centisome position: 73.32
GC content: 33.38
Gene sequence:
>2094_bases ATGAATAAAAGAGGTCTTTATTCAAAACTAGGAATTTCTGTTGTAGGCATTAGTCTTTTAATGGGAGTCCCCACTTTGAT TCATGCGAATGAATTAAACTATGGTCAACTGTCCATATCTCCTATTTTTCAAGGAGGCTCATATCAACTGAACAATAAGA GTATAGATATCAGCCCTTTGTTATTAGATAAATTGTCTGGAGAGAGTCAGACAGTAGTAATGAAATTTAAAGCAGATGAA CCAAACTCTCTTCAAGCTTTGTTTGGCCTATCTAATAGTAAAGCAGGCTTTAAAAATAATTACTTTTCAATTTTCATGAG AGATTCTGGTGAGATAGGTGTAGAAATAAGAGACGCCCAAAAGGGAATAAATTATTTATTTTCCAGACCAGCTTCATTAT GGGGAAAACATAAAGGACAGGCAGTTGAAAATACACTAGTATTTGTATCTGATTCTAAAGATAAAACATACACAATGTAT GTTAATGGAATAGAAGTGTTCTCTGAAACAGTTGATACATTTTTGCCAATTTCAAATATAAATGGTATAGATAAGGCAAC ACTAGGAGCTGTTAATCGTGAAGGTAAGGAACATTACCTCGCAAAAGGAAGTATTGGTGAAATCAGTCTATTTAACAAAG CAATTAGTGATCAGGAAGTTTCAACTATTCCCTTGTCAAATCCATTTCAGTTAATTTTCCAATCAGGAGATTCTACTCAA GCTAACTATTTTAGAATACCGACACTATATACATTAAGTAGTGGAAGAGTTCTATCAAGTATTGATGCACGTTATGGTGG GACTCATGATTCTAAAAGTAAGATTAATATTGCCACTTCTTATAGTGATGATAATGGGAAAACGTGGAGTGAGCCAATTT TTGCTATGAAGTTTAATGACTATGAGGAGCAGTTAGTTTACTGGCCACGAGATAATAAATTAAAGAATAGTCAAATTAGT GGAAGTGCTTCATTCATAGATTCATCCATTGTTGAAGATAAAAAATCTGGGAAAACGATATTACTAGCTGATGTTATGCC TGCGGGTATTGGAAATAATAATGCAAATAAAGCCGACTCAGGTTTTAAAGAAATAAATGGTCATTATTATTTAAAACTAA AGAAGAATGGAGATAACGATTTCCGTTATACAGTTAGAGAAAATGGTGTCGTTTATGATGAAACAACTAATAAACCTACA AATTATACTATAAATGATAAGTATGAAGTTTTGGAGGGAGGAAAGTCTTTAACAGTCGAACAATATTCGGTTGATTTTGA TAGTGGCTCTTTAAGAGAAAAACATAATGGAAAACAGGTCCCTATGAATGTTTTCTATAAAGATTCGTTATTTAAAGTGA CTCCTACTAATTATATAGCAATGACAACTAGTCAGAATAGAGGAGAGAGTTGGGAACAATTTAAGTTGTTGCCTCCGTTC TTAGGAGAAAAACATAATGGAACTTACTTATGTCCCGGACAAGGTTTAGCATTAAAATCAAGTAACAGATTGATTTTTGC AACATATACTAGTGGAGAACTAACCTATCTCATTTCTGATGATAGTGGTCAAACATGGAAGAAATCCTCAGCTTCAATTC CGTTTAAAAATGCAACAGCAGAAGCACAAATGGTTGAACTGAGAGATGGTGTGATTAGAACATTCTTTAGAACCACTACA GGTAAGATAGCTTATATGACTAGTAGAGATTCTGGAGAAACATGGTCGGAAGTTTCGTATATTGATGGAATCCAACAAAC TTCATATGGCACACAAGTATCTGCAATTAAATACTCTCAATTAATTGATGGAAAAGAAGCAGTCATTTTGAGTACACCAA ATTCTAGAAGTGGCCGTAAGGGAGGTCAATTAGTTGTCGGTTTAGTCAATAAAGAAGATGATAGTATTGATTGGAAATAC CACTATGATATTGATTTGCCTTCGTATGGTTATGCCTATTCTGCGATTACAGAATTGCCAAATCATCACATAGGTGTACT GTTTGAAAAATATGATTCGTGGTCGAGAAATGAATTGCATTTAAGCAATGTAGTTCAGTATATAGATTTGGAAATTAATG ATTTAACAAAATAA
Upstream 100 bases:
>100_bases TTGTAGTTCTTCCATCAATTATTTTCTTCTCTATCATCCAAAATAAGATTGCAAGTGGATTATCAGAAGGATCTGTGAAG TAGACGAAAGAAGGAAAAAA
Downstream 100 bases:
>100_bases AGGAGAAAAACATGGTTAAATACGGTGTTGTTGGAGCAGGGTATTTTGGAGCTGAATTGGCTCGCTACATGCAAAAGAAT GATGGAGCAGAGATTACTCT
Product: sialidase B precursor (neuraminidase B)
Products: NA
Alternate protein names: Neuraminidase B [H]
Number of amino acids: Translated: 697; Mature: 697
Protein sequence:
>697_residues MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADE PNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQEVSTIPLSNPFQLIFQSGDSTQ ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQIS GSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPT NYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTT GKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKY HYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK
Sequences:
>Translated_697_residues MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADE PNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQEVSTIPLSNPFQLIFQSGDSTQ ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQIS GSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPT NYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTT GKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKY HYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK >Mature_697_residues MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADE PNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQEVSTIPLSNPFQLIFQSGDSTQ ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQIS GSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPT NYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTT GKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKY HYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK
Specific function: Unknown
COG id: COG4409
COG function: function code G; Neuraminidase (sialidase)
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 4 BNR repeats [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002860 - InterPro: IPR008985 - InterPro: IPR013320 - InterPro: IPR004124 - InterPro: IPR011040 [H]
Pfam domain/function: PF02012 BNR; PF02973 Sialidase [H]
EC number: =3.2.1.18 [H]
Molecular weight: Translated: 77623; Mature: 77623
Theoretical pI: Translated: 6.46; Mature: 6.46
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.7 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPL CCCCCCHHHHCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCCEEECCCCEECCHH LLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQ HHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECHH KGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMYVNGIEVFSETVDTFLPISNI HHHHHHHCCCHHHHCCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHCCCCCC NGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQEVSTIPLSNPFQLIFQSGDSTQ CCCCHHHHCCCCCCCCCEEEECCCCCEEEHHHHHCCCCCEEEECCCCCEEEEEECCCCCC ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFND CCEEECCEEEEECCCCEEEECHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECC YEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADS CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC GFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPTNYTINDKYEVLEGGKSLTVE CHHHCCCEEEEEEEECCCCCEEEEEECCCEEEECCCCCCCCEEECCCCEEECCCCEEEEE QYSVDFDSGSLREKHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF EEEEECCCCCCHHHCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCCHHEEECCHH LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATA HCCCCCCCEEECCCCEEEECCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCC EAQMVELRDGVIRTFFRTTTGKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQ CHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCHHCCCCCEEEEEEHHH LIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELP HCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHCC NHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK CCCEEEEEEECCCCCCCEEEHHHHEEEEEEEECCCCC >Mature Secondary Structure MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISPL CCCCCCHHHHCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCCEEECCCCEECCHH LLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQ HHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECHH KGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMYVNGIEVFSETVDTFLPISNI HHHHHHHCCCHHHHCCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHCCCCCC NGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQEVSTIPLSNPFQLIFQSGDSTQ CCCCHHHHCCCCCCCCCEEEECCCCCEEEHHHHHCCCCCEEEECCCCCEEEEEECCCCCC ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFND CCEEECCEEEEECCCCEEEECHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECC YEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADS CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC GFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPTNYTINDKYEVLEGGKSLTVE CHHHCCCEEEEEEEECCCCCEEEEEECCCEEEECCCCCCCCEEECCCCEEECCCCEEEEE QYSVDFDSGSLREKHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF EEEEECCCCCCHHHCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCCHHEEECCHH LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATA HCCCCCCCEEECCCCEEEECCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCC EAQMVELRDGVIRTFFRTTTGKIAYMTSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQ CHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCHHCCCCCEEEEEEHHH LIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELP HCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHCC NHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK CCCEEEEEEECCCCCCCEEEHHHHEEEEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8759848; 11463916 [H]