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The map label for this gene is galE [H]

Identifier: 221232362

GI number: 221232362

Start: 1560146

End: 1561165

Strand: Reverse

Name: galE [H]

Synonym: SPN23F_16210

Alternate gene names: 221232362

Gene position: 1561165-1560146 (Counterclockwise)

Preceding gene: 221232363

Following gene: 221232361

Centisome position: 70.28

GC content: 43.73

Gene sequence:

>1020_bases
ATGCAAGAAAAGATTTTGGTAACTGGTGGTGCCGGTTTTATTGGAACCCACACTGTTATTGAATTGATCCAAGCAGGCCA
TCAAGTTGTTGTGGTGGATAATCTTGTCAATAGCAATCGTAAGAGTTTAGAAGTTGTTGAAAGAATCACAGGAGTTGAGA
TTCCTTTCTATGAGGCAGATATTCGTGACACAGCTACCCTCAGAGATATTTTCAAGCAGGAAGAACCGACTGGTGTCATT
CACTTTGCTGGTTTGAAGGCTGTTGGCGAATCAACACGTATCCCTCTTGCCTACTATGACAACAATATCGCTGGAACTGT
CAGCCTTTTGAAAGCCATGGAAGAAAACAACTGTAAAAACATCATCTTCAGTTCTTCTGCGACAGTTTACGGGGATCCGC
ACACAGTGCCCATCTTGGAAGATTTCCCACTTTCAGTGACCAACCCATACGGTCGTACTAAGCTCATGCTAGAGGAAATT
TTGACTGATATTTACAAAGCAGACTCAGAATGGAATGTTGTCTTGCTTCGTTACTTTAACCCAATCGGAGCCCATGAGAG
TGGTGATTTGGGAGAAAATCCAAACGGTATTCCAAACAATCTCTTGCCATATGTGACTCAAGTAGCCGTTGGAAAATTAG
AGCAAGTGCAAGTGTTTGGAGACGATTACGATACGGAAGATGGAACAGGTGTTCGTGACTATATCCACGTTGTCGATTTG
GCTAAGGGTCACGTTGCAGCTTTGAAAAAAATCCAAAAAGGTTCAGGACTAAACGTTTATAACCTTGGAACTGGTAAAGG
TTACTCAGTTCTTGAAATTATCCAAAACATGGAAAAAGCGGTGGGCCGTCCTATTCCTTACCGCATCGTAGAACGTCGCC
CAGGTGATATCGCTGCCTGCTACTCAGACCCGGCAAAAGCTAAAGCAGAACTCGGTTGGGAAGCAGAACTCGACATCACC
CAAATGTGTGAAGACGCATGGCGTTGGCAAAGCAAGCATCCAAATGGATTTGAAGACTAA

Upstream 100 bases:

>100_bases
ATTTTACTGAAATTTTATCAGGTAGTTTAGGATGGCAAATGACATTCCCTGTCAAAAATGGTAAAATAAGAAAAAATAAT
CTGAGAATCGAGGAAAAAAG

Downstream 100 bases:

>100_bases
GATGATGATTTCAATCATCGTCCCTTGTTTAAACGAAGAGGAAGTACTTCCTCTTTTTTATCAGGCTCTGGAAGCTTTAC
TTCCAGATTTGGAAACAGAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVI
HFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDIT
QMCEDAWRWQSKHPNGFED

Sequences:

>Translated_339_residues
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVI
HFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDIT
QMCEDAWRWQSKHPNGFED
>Mature_339_residues
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVI
HFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDIT
QMCEDAWRWQSKHPNGFED

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=57.5581395348837, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=57.5581395348837, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=57.5581395348837, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI7657641, Length=278, Percent_Identity=25.1798561151079, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI42516563, Length=319, Percent_Identity=25.705329153605, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=53.4124629080119, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=29.3413173652695, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788353, Length=346, Percent_Identity=29.4797687861272, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=52.6162790697674, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71982038, Length=346, Percent_Identity=52.3121387283237, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17568069, Length=338, Percent_Identity=24.5562130177515, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=53.3527696793003, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=53.4883720930233, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI21356223, Length=324, Percent_Identity=24.0740740740741, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37435; Mature: 37435

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEAD
CCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECHHCCCHHHHHHHHHHHCCCCCEEECC
IRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKN
CCHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCE
IIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEILTDIYKADSEWNVVLLRYFN
EEEECCEEEECCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECC
PIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGRPIPYRIVERRPGDIAAC
CCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEEE
YSDPAKAKAELGWEAELDITQMCEDAWRWQSKHPNGFED
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEAD
CCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECHHCCCHHHHHHHHHHHCCCCCEEECC
IRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKN
CCHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCE
IIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEILTDIYKADSEWNVVLLRYFN
EEEECCEEEECCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECC
PIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGRPIPYRIVERRPGDIAAC
CCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEEE
YSDPAKAKAELGWEAELDITQMCEDAWRWQSKHPNGFED
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]