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The map label for this gene is dnaC [H]

Identifier: 220933146

GI number: 220933146

Start: 2528010

End: 2529392

Strand: Direct

Name: dnaC [H]

Synonym: Hore_23140

Alternate gene names: 220933146

Gene position: 2528010-2529392 (Clockwise)

Preceding gene: 220933145

Following gene: 220933147

Centisome position: 98.06

GC content: 47.87

Gene sequence:

>1383_bases
ATGGCTACTGAAGAAAGGTATTTACAACAGTTTAATAATGTCCAGGAACAGGAGTTCCAGCTTTTAGGAATACTCCTTCA
GTATCCCCAGAAGATAGACGAGATTGCTGATTCCCTGGAGGTTAAACACTTTCAGGACCCCCAGGCCCAGCTCATCTATG
AAATCCTGTTAAACCAGTTCCAGCGTGATAACCAGATTTCCCGGACCAAACTCTTTTTACGCTTAAAACAGGATGGGGTT
ATAAAAAAACCGGAGGAAACAATTGAACGCTTAACCTCAGGGTTCAGTACCGTTGATGAATTAAAACCAACTATTGACCT
CATAAAACAGAATTACCAGCGGCGCCTCCTGGTCAAAGCAGCCCGCAAGATCCAGGAGCTGGCCGCTAAAGACTTAGATA
TAGATGATTTCCAGGCCCGGGCCCAGGAGTTAATCTTTGAGGCCACCAATGAAACCACCGACCTGGAAAAACATATTTTC
ACCATGGAAGAGGCCCTGATGAAGTCCTTTGAGGCCTATATTGACCGGAAACATAACCAGGCCGATGTCGGCCTCCCCAC
CGGCTTTATCTCCCTGGATAACCTCATCGGGGGCTTTAAAAAGGGCCATCTCAATGTTATTGCCGCTTCCACCAGTATGG
GAAAGACGGCCTTTGCCATCAATATCGCCAAGAATGTTTTAAAGAGGAATGTCCCCGTTGCTATTATCAGTCTGGAGATG
GATGCCCAGGAGATCATAGACCGGATGATTATTCAGGAATCCGGGGTTAATGGATGGAAATATAACCAGGGCCAGACCAG
TGATGAGGAAGATAAACGGATTTCGAAAGCCCTGGATAACCTCCATGAACTACCCCTTATGATTTCTGATGAAAGGGGTC
TAAATGTGGCCCAGATCCGGGCCCGGCTGCGAAAATTCAAGGCCCAGATGGGAGACCTGGGACTGGTAATTATCGACTAC
CTCCAGATGATCCAGTTACCTGAAGAACATGCCCAGAACACGGCCAGAGCTGTTGGACAGATAGTCCTCCAGCTGCGTAA
TATGGCCTCTGAGCTTGAGGTTCCCATTATCCTCATCTCCCAGATCAGCCGTAGTTTTACAAACCGTCAGGATAAAAGAC
CCGTCCTTTCTGACCTCAGGGATTCCGGTAACATTGAGGAAATTGCTGACGGGGTCATCTTCCTCTACCGGCATGCCCAT
ACCAGTGCTGCCGCCCGGGAACAGGCAGAAAAAGAAGGTACTGAAAACGATACTGAAGTAATTGTGGCCAAGCAGAGAAC
CGGCCAGACCGGTGCCATCAAACTTTATTTTGAAGATGAGTTTATCCGTTTTATCGACCCTGAAAACCTCTCGGTTGAAG
CCAGTATGCCTGGTCAGGGTTAA

Upstream 100 bases:

>100_bases
AGAGAATTTTCCAGCGGCTTATTGAAATGAACCGTTATGTCTGCCTCTACGGTGATGTCAGAGCCAAAATAGTCGCCGGG
CAACAGGAGGTTAACCTCTA

Downstream 100 bases:

>100_bases
GGACCACTATCACTTAATAAGAATTTAAAGGAAAGGGAGCCCACCCATGTTAGACAAAAAGAATATCGACCTCAAGATTA
TCCTCTCCTTCGTCAATGCC

Product: DnaB domain-containing protein helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MATEERYLQQFNNVQEQEFQLLGILLQYPQKIDEIADSLEVKHFQDPQAQLIYEILLNQFQRDNQISRTKLFLRLKQDGV
IKKPEETIERLTSGFSTVDELKPTIDLIKQNYQRRLLVKAARKIQELAAKDLDIDDFQARAQELIFEATNETTDLEKHIF
TMEEALMKSFEAYIDRKHNQADVGLPTGFISLDNLIGGFKKGHLNVIAASTSMGKTAFAINIAKNVLKRNVPVAIISLEM
DAQEIIDRMIIQESGVNGWKYNQGQTSDEEDKRISKALDNLHELPLMISDERGLNVAQIRARLRKFKAQMGDLGLVIIDY
LQMIQLPEEHAQNTARAVGQIVLQLRNMASELEVPIILISQISRSFTNRQDKRPVLSDLRDSGNIEEIADGVIFLYRHAH
TSAAAREQAEKEGTENDTEVIVAKQRTGQTGAIKLYFEDEFIRFIDPENLSVEASMPGQG

Sequences:

>Translated_460_residues
MATEERYLQQFNNVQEQEFQLLGILLQYPQKIDEIADSLEVKHFQDPQAQLIYEILLNQFQRDNQISRTKLFLRLKQDGV
IKKPEETIERLTSGFSTVDELKPTIDLIKQNYQRRLLVKAARKIQELAAKDLDIDDFQARAQELIFEATNETTDLEKHIF
TMEEALMKSFEAYIDRKHNQADVGLPTGFISLDNLIGGFKKGHLNVIAASTSMGKTAFAINIAKNVLKRNVPVAIISLEM
DAQEIIDRMIIQESGVNGWKYNQGQTSDEEDKRISKALDNLHELPLMISDERGLNVAQIRARLRKFKAQMGDLGLVIIDY
LQMIQLPEEHAQNTARAVGQIVLQLRNMASELEVPIILISQISRSFTNRQDKRPVLSDLRDSGNIEEIADGVIFLYRHAH
TSAAAREQAEKEGTENDTEVIVAKQRTGQTGAIKLYFEDEFIRFIDPENLSVEASMPGQG
>Mature_459_residues
ATEERYLQQFNNVQEQEFQLLGILLQYPQKIDEIADSLEVKHFQDPQAQLIYEILLNQFQRDNQISRTKLFLRLKQDGVI
KKPEETIERLTSGFSTVDELKPTIDLIKQNYQRRLLVKAARKIQELAAKDLDIDDFQARAQELIFEATNETTDLEKHIFT
MEEALMKSFEAYIDRKHNQADVGLPTGFISLDNLIGGFKKGHLNVIAASTSMGKTAFAINIAKNVLKRNVPVAIISLEMD
AQEIIDRMIIQESGVNGWKYNQGQTSDEEDKRISKALDNLHELPLMISDERGLNVAQIRARLRKFKAQMGDLGLVIIDYL
QMIQLPEEHAQNTARAVGQIVLQLRNMASELEVPIILISQISRSFTNRQDKRPVLSDLRDSGNIEEIADGVIFLYRHAHT
SAAAREQAEKEGTENDTEVIVAKQRTGQTGAIKLYFEDEFIRFIDPENLSVEASMPGQG

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=290, Percent_Identity=35.5172413793103, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 52339; Mature: 52208

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEERYLQQFNNVQEQEFQLLGILLQYPQKIDEIADSLEVKHFQDPQAQLIYEILLNQF
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QRDNQISRTKLFLRLKQDGVIKKPEETIERLTSGFSTVDELKPTIDLIKQNYQRRLLVKA
HCCCCHHHHHHHHEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARKIQELAAKDLDIDDFQARAQELIFEATNETTDLEKHIFTMEEALMKSFEAYIDRKHNQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ADVGLPTGFISLDNLIGGFKKGHLNVIAASTSMGKTAFAINIAKNVLKRNVPVAIISLEM
CCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECC
DAQEIIDRMIIQESGVNGWKYNQGQTSDEEDKRISKALDNLHELPLMISDERGLNVAQIR
CHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHH
ARLRKFKAQMGDLGLVIIDYLQMIQLPEEHAQNTARAVGQIVLQLRNMASELEVPIILIS
HHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QISRSFTNRQDKRPVLSDLRDSGNIEEIADGVIFLYRHAHTSAAAREQAEKEGTENDTEV
HHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IVAKQRTGQTGAIKLYFEDEFIRFIDPENLSVEASMPGQG
EEEECCCCCCCEEEEEEECCCCEEECCCCCEEEECCCCCC
>Mature Secondary Structure 
ATEERYLQQFNNVQEQEFQLLGILLQYPQKIDEIADSLEVKHFQDPQAQLIYEILLNQF
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QRDNQISRTKLFLRLKQDGVIKKPEETIERLTSGFSTVDELKPTIDLIKQNYQRRLLVKA
HCCCCHHHHHHHHEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARKIQELAAKDLDIDDFQARAQELIFEATNETTDLEKHIFTMEEALMKSFEAYIDRKHNQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ADVGLPTGFISLDNLIGGFKKGHLNVIAASTSMGKTAFAINIAKNVLKRNVPVAIISLEM
CCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECC
DAQEIIDRMIIQESGVNGWKYNQGQTSDEEDKRISKALDNLHELPLMISDERGLNVAQIR
CHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHH
ARLRKFKAQMGDLGLVIIDYLQMIQLPEEHAQNTARAVGQIVLQLRNMASELEVPIILIS
HHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QISRSFTNRQDKRPVLSDLRDSGNIEEIADGVIFLYRHAHTSAAAREQAEKEGTENDTEV
HHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IVAKQRTGQTGAIKLYFEDEFIRFIDPENLSVEASMPGQG
EEEECCCCCCCEEEEEEECCCCEEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]