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The map label for this gene is murB [H]

Identifier: 220933051

GI number: 220933051

Start: 2417354

End: 2418268

Strand: Direct

Name: murB [H]

Synonym: Hore_22190

Alternate gene names: 220933051

Gene position: 2417354-2418268 (Clockwise)

Preceding gene: 220933040

Following gene: 220933052

Centisome position: 93.76

GC content: 42.3

Gene sequence:

>915_bases
ATGTCCATCAATAACAAGTTATTAGATATATTAAAAGAAATTAATGGCCTTGAAGTCAAAAAAGGGATCCCATTAAAACA
ATACACATCATTTAAAATAGGGGGTCCAGCGGAACTCTTTCTGGTACCATCAAATATTACTGCCCTCAAAAAGGCAGTAA
AAATCCTTTTTAATAATAACTTACCTTATTTCGTACTGGGCCGGGGCAGTAATATTATCGTCAGTGACAAAGGTTATAAT
GGAGTTGTTATTTATCTCGGCAAACTTGATAAAATTACAGTTGAGGAAACCCGGGTTACTTCTGAATGTGGGGTTACCCT
GGCCCGCCTGGCGGGACGGGTTGCCGAGGCAGGGCTTACAGGACTGGAGTTTGCCAGTGGAATACCCGGCTCCCTGGGTG
GAGCCCTTTACATGAATGCCGGGGCTTACGGTGGAGAAATGAAAGATGTTGTAAAGGAAGTAGTAGTCGTTGATAAAACC
GGAAAAGAGATTAGTATCAAAGCACCGGAACTTAAATTTTCTTACCGCCACAGCGTCCTCCAGGAAAAACACTATATAGC
TGTCAAAGCTGTTCTTGAATTAAAAAAAGGTAACAGGGAAAAAATAAAAACCAGAATGAAGGAACTGAATGAAAAACGAA
AACAAAAACAACCCCTGGAGTGGCCCAGTGCCGGAAGTGCTTTTAAACGTCCTGAAGGCTATTACGCCGGAAAACTTATC
GAAGACGCCGGCTTAAAGGGCCTGAGGGTAGGGGATGCCCAGGTGTCTACCAAACATGCCGGATTTATTATCAACCTGGG
AGAAGCCACCGCAAGCGATGTCAGGAAGTTAATGAATAAAATTCAGCAGAAAGTATATGACAAAAACGGGGTTCTTCTGG
AACCTGAACCTAAATTTATCGGTGATTTTGAATAA

Upstream 100 bases:

>100_bases
CCATTACAGGGAGTCATTTATTATAAGAATTAAATATAATTTTTAAGAAAGGTCGGAAAAAGTCCAGATCTTACTAAAAT
ATTCGGGGAGTGTCCACTAT

Downstream 100 bases:

>100_bases
ATTCCACCCCGGGAAACCGGGGTCTTTTCTTTTTTTCTATCCTGACCCGACCCCGGGTATATTCTGAGATAAAATGAAGC
ATATCGGGGTTATAATACAA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSINNKLLDILKEINGLEVKKGIPLKQYTSFKIGGPAELFLVPSNITALKKAVKILFNNNLPYFVLGRGSNIIVSDKGYN
GVVIYLGKLDKITVEETRVTSECGVTLARLAGRVAEAGLTGLEFASGIPGSLGGALYMNAGAYGGEMKDVVKEVVVVDKT
GKEISIKAPELKFSYRHSVLQEKHYIAVKAVLELKKGNREKIKTRMKELNEKRKQKQPLEWPSAGSAFKRPEGYYAGKLI
EDAGLKGLRVGDAQVSTKHAGFIINLGEATASDVRKLMNKIQQKVYDKNGVLLEPEPKFIGDFE

Sequences:

>Translated_304_residues
MSINNKLLDILKEINGLEVKKGIPLKQYTSFKIGGPAELFLVPSNITALKKAVKILFNNNLPYFVLGRGSNIIVSDKGYN
GVVIYLGKLDKITVEETRVTSECGVTLARLAGRVAEAGLTGLEFASGIPGSLGGALYMNAGAYGGEMKDVVKEVVVVDKT
GKEISIKAPELKFSYRHSVLQEKHYIAVKAVLELKKGNREKIKTRMKELNEKRKQKQPLEWPSAGSAFKRPEGYYAGKLI
EDAGLKGLRVGDAQVSTKHAGFIINLGEATASDVRKLMNKIQQKVYDKNGVLLEPEPKFIGDFE
>Mature_303_residues
SINNKLLDILKEINGLEVKKGIPLKQYTSFKIGGPAELFLVPSNITALKKAVKILFNNNLPYFVLGRGSNIIVSDKGYNG
VVIYLGKLDKITVEETRVTSECGVTLARLAGRVAEAGLTGLEFASGIPGSLGGALYMNAGAYGGEMKDVVKEVVVVDKTG
KEISIKAPELKFSYRHSVLQEKHYIAVKAVLELKKGNREKIKTRMKELNEKRKQKQPLEWPSAGSAFKRPEGYYAGKLIE
DAGLKGLRVGDAQVSTKHAGFIINLGEATASDVRKLMNKIQQKVYDKNGVLLEPEPKFIGDFE

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=328, Percent_Identity=28.3536585365854, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33312; Mature: 33181

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINNKLLDILKEINGLEVKKGIPLKQYTSFKIGGPAELFLVPSNITALKKAVKILFNNN
CCCCHHHHHHHHHCCCCEECCCCCHHHCCCEECCCCEEEEEECCCHHHHHHHHHHHCCCC
LPYFVLGRGSNIIVSDKGYNGVVIYLGKLDKITVEETRVTSECGVTLARLAGRVAEAGLT
CCEEEEECCCEEEEECCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLEFASGIPGSLGGALYMNAGAYGGEMKDVVKEVVVVDKTGKEISIKAPELKFSYRHSVL
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHEEECCCCCEEEEECCCEEHHHHHHHH
QEKHYIAVKAVLELKKGNREKIKTRMKELNEKRKQKQPLEWPSAGSAFKRPEGYYAGKLI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
EDAGLKGLRVGDAQVSTKHAGFIINLGEATASDVRKLMNKIQQKVYDKNGVLLEPEPKFI
CCCCCCCEEECCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
GDFE
CCCC
>Mature Secondary Structure 
SINNKLLDILKEINGLEVKKGIPLKQYTSFKIGGPAELFLVPSNITALKKAVKILFNNN
CCCHHHHHHHHHCCCCEECCCCCHHHCCCEECCCCEEEEEECCCHHHHHHHHHHHCCCC
LPYFVLGRGSNIIVSDKGYNGVVIYLGKLDKITVEETRVTSECGVTLARLAGRVAEAGLT
CCEEEEECCCEEEEECCCCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLEFASGIPGSLGGALYMNAGAYGGEMKDVVKEVVVVDKTGKEISIKAPELKFSYRHSVL
HHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHEEECCCCCEEEEECCCEEHHHHHHHH
QEKHYIAVKAVLELKKGNREKIKTRMKELNEKRKQKQPLEWPSAGSAFKRPEGYYAGKLI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
EDAGLKGLRVGDAQVSTKHAGFIINLGEATASDVRKLMNKIQQKVYDKNGVLLEPEPKFI
CCCCCCCEEECCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
GDFE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]