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The map label for this gene is mcp4 [H]

Identifier: 220933031

GI number: 220933031

Start: 2393725

End: 2395539

Strand: Direct

Name: mcp4 [H]

Synonym: Hore_21990

Alternate gene names: 220933031

Gene position: 2393725-2395539 (Clockwise)

Preceding gene: 220933028

Following gene: 220933032

Centisome position: 92.85

GC content: 37.58

Gene sequence:

>1815_bases
ATGAAAGGAACTGTAGTTTCAACCTGGATTAATACCCTTAACGAAATATACGGGGAGGACCTGGTAAACCAGGCCAAAGC
TGACTCAAGCTGGAATGAAGAACTTATTATCACCTCCCTAATGGATATTGAAGATAAAAAAGTTTTTGATCTAATTAACA
CAGTAGCCAACCTGGTCGATAAATCACCAGGTGAGTTATGGCAGGAAATTGGTCGCCATAATATAAAATCCTTCTCCAAA
TGGTTTCCATCATATTTTGAAGGTAGAACCCTGAAAAATTTTTTAATGATGATGGATACTGTACATAAACAATTAACCCA
GATGATTCCCGGGGCTAACCCTCCCCGAATCATAGCTGAACAAACCGGTGATCGAACCCTGGAAATCACCTATATATCCC
CACGGGGAATGTATGACTACTTTCTGGGGCTGATTGAAGGGAGTTCTGAATTTTTCTCTGACCCCATTGAAGTAACTGAA
CTGGGTCGAGGAGAATCAGAGCAGGGAAAATATTTAAAGGTAAATATTGAATTCTCTCACAGTTTATCAGATAAATATAA
CTACAGAATCAGTAAGCTCTTTTCCCTGGGTATATTTAAAAGTATTAAATTAAAGGCTACAATTATGGTTATGCTGGCAT
CCCTGGGTGTTTATTATGGACTAAGTTTTACCTCAGGGAATTGGTGGTCTCCTCTATTGCAGACTGCCTGCTTAGGATTA
ATTACCTTTGTCTTCATGGGATTTTTCACTTCACCCTTCAAAAAATTAAATAAAGCCCTTGTTAGTCTGAGGGGCTTAAA
ATTTGGTGAAACCCTCTCTATATCTACCAATGATGAATTTGAAAGGATCTTTAAACAGCTGGATGGGATAAAAAATGAAA
TAAAGGAAGACATCCTCTTTTTAAAGGGTGGAACCGATGATATGTATAACTTTACAAACCAGTTTGTAGAAATTGCCGAT
AAAATGAATGTTGTCTCTGATAACATTTCAAAAGTAGTCGAGGAAGTAGCCAACGGGGCCCAGGAGCAGGCAGCTGAAAC
TGAAAACTCAGCCTATATAGTTGATAATAATATAAAGAAGATTGAAGAACTTGTAGAATCCGGTAATGATAGCAAGAAAA
ACCTGGAAGAAGCCGTTGAAAATATAAAACAGTCAGCCCGGGAAGTCCAGAATGTGAACGAAATGATTGATTCAGTTAAA
AATGCCTTTTCCAATGTAAATAGCCTTGGTAAAAAACTGGCCCAGAGAATCAGTGACATTATGGAAATTGTAAATACCGT
CTCTGATATTGCCAATCAAACCAATCTATTATCACTAAATGCTTCTATAGAGGCTGCCCGTTCCAATGATAACAGCCGGG
GCTTTGCTGTAGTTGCAGAAGAAATCAGGGAATTGGCCGAAGATTCCAAACAGGCCGGTAACACCATAAATGAAAATCTG
GCCCAGTTTACCGAGCAGGTCCAGGAGTTAATTGATGGCATCAGTTCCCAGTTTGCTAACCTTGAACACAGTAATAAGGT
CTTATCTGAAGTAGCCAGTTCAAATAAAAAATCCAGTGAAAATATCCAGGAAGCTACCGATAATGTAGTCAGTATTGTTG
AAAATCTTGATACAGAAACCAAAAAAATAATTAAAGTTATTGAAAATATTAATTCATTAGCTGCTATTGCCCAGGAGAAT
TCAGCATCCTCTGAGGAAATGAGTGCCAGTGTTAACGAATATTCAGAAAAAATCAAAGAGATGACTTCATATATTAACCA
GATGGAAAAACTGGTGGAAAACTTTAAAGAAAACCTTAAAAAATACAACATCTAG

Upstream 100 bases:

>100_bases
TTTGAAATAAAAAAAGGTTTTTTCTGTATTTATGTCTAATATATATTTAACCAAAATAAATGTCTATTTATTCTAATCTT
TAAATTAAAGGAGGTCTTCG

Downstream 100 bases:

>100_bases
GTTGCTTCACCTTTTTTAATTATGGTCAACAATTGCAAGAACAACTGAATATAAAAAACAGGCCCCGGCCATTACCGGGG
CCTTTATTATGTGAATAAAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MKGTVVSTWINTLNEIYGEDLVNQAKADSSWNEELIITSLMDIEDKKVFDLINTVANLVDKSPGELWQEIGRHNIKSFSK
WFPSYFEGRTLKNFLMMMDTVHKQLTQMIPGANPPRIIAEQTGDRTLEITYISPRGMYDYFLGLIEGSSEFFSDPIEVTE
LGRGESEQGKYLKVNIEFSHSLSDKYNYRISKLFSLGIFKSIKLKATIMVMLASLGVYYGLSFTSGNWWSPLLQTACLGL
ITFVFMGFFTSPFKKLNKALVSLRGLKFGETLSISTNDEFERIFKQLDGIKNEIKEDILFLKGGTDDMYNFTNQFVEIAD
KMNVVSDNISKVVEEVANGAQEQAAETENSAYIVDNNIKKIEELVESGNDSKKNLEEAVENIKQSAREVQNVNEMIDSVK
NAFSNVNSLGKKLAQRISDIMEIVNTVSDIANQTNLLSLNASIEAARSNDNSRGFAVVAEEIRELAEDSKQAGNTINENL
AQFTEQVQELIDGISSQFANLEHSNKVLSEVASSNKKSSENIQEATDNVVSIVENLDTETKKIIKVIENINSLAAIAQEN
SASSEEMSASVNEYSEKIKEMTSYINQMEKLVENFKENLKKYNI

Sequences:

>Translated_604_residues
MKGTVVSTWINTLNEIYGEDLVNQAKADSSWNEELIITSLMDIEDKKVFDLINTVANLVDKSPGELWQEIGRHNIKSFSK
WFPSYFEGRTLKNFLMMMDTVHKQLTQMIPGANPPRIIAEQTGDRTLEITYISPRGMYDYFLGLIEGSSEFFSDPIEVTE
LGRGESEQGKYLKVNIEFSHSLSDKYNYRISKLFSLGIFKSIKLKATIMVMLASLGVYYGLSFTSGNWWSPLLQTACLGL
ITFVFMGFFTSPFKKLNKALVSLRGLKFGETLSISTNDEFERIFKQLDGIKNEIKEDILFLKGGTDDMYNFTNQFVEIAD
KMNVVSDNISKVVEEVANGAQEQAAETENSAYIVDNNIKKIEELVESGNDSKKNLEEAVENIKQSAREVQNVNEMIDSVK
NAFSNVNSLGKKLAQRISDIMEIVNTVSDIANQTNLLSLNASIEAARSNDNSRGFAVVAEEIRELAEDSKQAGNTINENL
AQFTEQVQELIDGISSQFANLEHSNKVLSEVASSNKKSSENIQEATDNVVSIVENLDTETKKIIKVIENINSLAAIAQEN
SASSEEMSASVNEYSEKIKEMTSYINQMEKLVENFKENLKKYNI
>Mature_604_residues
MKGTVVSTWINTLNEIYGEDLVNQAKADSSWNEELIITSLMDIEDKKVFDLINTVANLVDKSPGELWQEIGRHNIKSFSK
WFPSYFEGRTLKNFLMMMDTVHKQLTQMIPGANPPRIIAEQTGDRTLEITYISPRGMYDYFLGLIEGSSEFFSDPIEVTE
LGRGESEQGKYLKVNIEFSHSLSDKYNYRISKLFSLGIFKSIKLKATIMVMLASLGVYYGLSFTSGNWWSPLLQTACLGL
ITFVFMGFFTSPFKKLNKALVSLRGLKFGETLSISTNDEFERIFKQLDGIKNEIKEDILFLKGGTDDMYNFTNQFVEIAD
KMNVVSDNISKVVEEVANGAQEQAAETENSAYIVDNNIKKIEELVESGNDSKKNLEEAVENIKQSAREVQNVNEMIDSVK
NAFSNVNSLGKKLAQRISDIMEIVNTVSDIANQTNLLSLNASIEAARSNDNSRGFAVVAEEIRELAEDSKQAGNTINENL
AQFTEQVQELIDGISSQFANLEHSNKVLSEVASSNKKSSENIQEATDNVVSIVENLDTETKKIIKVIENINSLAAIAQEN
SASSEEMSASVNEYSEKIKEMTSYINQMEKLVENFKENLKKYNI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=396, Percent_Identity=24.2424242424242, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788194, Length=474, Percent_Identity=21.7299578059072, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=23.1788079470199, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI2367378, Length=258, Percent_Identity=23.2558139534884, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789453, Length=271, Percent_Identity=25.830258302583, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 67815; Mature: 67815

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50234 VWFA ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTVVSTWINTLNEIYGEDLVNQAKADSSWNEELIITSLMDIEDKKVFDLINTVANLVD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHC
KSPGELWQEIGRHNIKSFSKWFPSYFEGRTLKNFLMMMDTVHKQLTQMIPGANPPRIIAE
CCHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
QTGDRTLEITYISPRGMYDYFLGLIEGSSEFFSDPIEVTELGRGESEQGKYLKVNIEFSH
CCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHCCCHHHHHCCCCCCCCCCEEEEEEEECC
SLSDKYNYRISKLFSLGIFKSIKLKATIMVMLASLGVYYGLSFTSGNWWSPLLQTACLGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ITFVFMGFFTSPFKKLNKALVSLRGLKFGETLSISTNDEFERIFKQLDGIKNEIKEDILF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHEE
LKGGTDDMYNFTNQFVEIADKMNVVSDNISKVVEEVANGAQEQAAETENSAYIVDNNIKK
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCHHH
IEELVESGNDSKKNLEEAVENIKQSAREVQNVNEMIDSVKNAFSNVNSLGKKLAQRISDI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEIVNTVSDIANQTNLLSLNASIEAARSNDNSRGFAVVAEEIRELAEDSKQAGNTINENL
HHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
AQFTEQVQELIDGISSQFANLEHSNKVLSEVASSNKKSSENIQEATDNVVSIVENLDTET
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
KKIIKVIENINSLAAIAQENSASSEEMSASVNEYSEKIKEMTSYINQMEKLVENFKENLK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYNI
HCCC
>Mature Secondary Structure
MKGTVVSTWINTLNEIYGEDLVNQAKADSSWNEELIITSLMDIEDKKVFDLINTVANLVD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHC
KSPGELWQEIGRHNIKSFSKWFPSYFEGRTLKNFLMMMDTVHKQLTQMIPGANPPRIIAE
CCHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
QTGDRTLEITYISPRGMYDYFLGLIEGSSEFFSDPIEVTELGRGESEQGKYLKVNIEFSH
CCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHCCCHHHHHCCCCCCCCCCEEEEEEEECC
SLSDKYNYRISKLFSLGIFKSIKLKATIMVMLASLGVYYGLSFTSGNWWSPLLQTACLGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ITFVFMGFFTSPFKKLNKALVSLRGLKFGETLSISTNDEFERIFKQLDGIKNEIKEDILF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHEE
LKGGTDDMYNFTNQFVEIADKMNVVSDNISKVVEEVANGAQEQAAETENSAYIVDNNIKK
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCHHH
IEELVESGNDSKKNLEEAVENIKQSAREVQNVNEMIDSVKNAFSNVNSLGKKLAQRISDI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEIVNTVSDIANQTNLLSLNASIEAARSNDNSRGFAVVAEEIRELAEDSKQAGNTINENL
HHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
AQFTEQVQELIDGISSQFANLEHSNKVLSEVASSNKKSSENIQEATDNVVSIVENLDTET
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
KKIIKVIENINSLAAIAQENSASSEEMSASVNEYSEKIKEMTSYINQMEKLVENFKENLK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYNI
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]