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The map label for this gene is ygbD [C]

Identifier: 220932932

GI number: 220932932

Start: 2275959

End: 2277308

Strand: Direct

Name: ygbD [C]

Synonym: Hore_21000

Alternate gene names: 220932932

Gene position: 2275959-2277308 (Clockwise)

Preceding gene: 220932928

Following gene: 220932935

Centisome position: 88.28

GC content: 42.15

Gene sequence:

>1350_bases
ATGAAAATAGCTATCATTGGCGGGGTTGCTGCCGGTACCAGTGCTGCTGCTAAAGCCCATCGCGAAAACCCTGAGGCAGA
AATTATACTATTTGAAAAGGATGAGAATATATCCTATGCCGGATGTGGACTTCCTTATTATATTTCCGGGGTTACAGACA
GCAGGCAGAAGGTAGTTATCAACACACCAGAGGCTTTTACCAAAAAATATAAAGTTGAAGTCCGGACCGGTCATAGAGTT
GATGAAATTATTCCTGATAAAAAATTAATAAGATACAGGAACTTAAAAAATAACAGGGATGGTGAATACCGGTATGATAA
ACTTATAATTACTACCGGGGCCAGTCCCGTAATACCTCCCATACCAGGGATAAAATTAAATAACATTCTCACCTTAAGAA
CTATTAACCATGCCGATATGATAAAAAATATTTTAAATAAAAATAAACCTGAAAGGGTCAGTATCATCGGAGCAGGCCTG
ATTGGACTGGAGATGGCTGAATCTTTCAGTAAACTGGGCCTTAAAGTGACAGTAATTGAAAAATTACCACAGGTTCTTCC
TCAGTTCAGTCCGGAAATGGCCCAAATTGTGGGTGCCCACCTGAAAGAAAATGGAGTAGATTTATTACTCAAAGACGGAG
TAGTTAAGTTTACAGGGGACAATTCTGTTGAAAAGGTAATTACCGAATCCGGACAGGAGATTAAGACCGACCTGGTTCTG
GTTTCAGTTGGTATTAGACCCAATGTTGAGCTGGCCCGTAAAGCCGGTATTAAAATTGGACCAACGGGAGCCATTGCCGT
TAATAACAAAATGCAAACCTCTTTATCTGACATCTATGCTGCTGGAGATTGTGCCGAGAGTACCGACCTTGTAAGCGGTA
AATCTATCTGGGCTCCCCTGGGTTCTACAGCCAATAAACAGGGACGGGTAGCCGGTGAAAATGCAGCCGGTGGAAATAAC
AGACATGATGGTGTCCTGAAGACTGCGATAACAAAAGTCTTTGATTTAACTGTGGCCAGAACGGGACTTTCTGAAAAAGA
AGCCAGTGAAGCCGGTTTTGACCCCATAGGTGTTAAAATCAAAGCTGTAAACCACGCCGGATATTATCCCGGCCTTGATA
AACTCCATATAAAAGGAGTTTTCGATAAAAAAACAAAACGAATTATCGGGGCTGAAGTTATCGGGAAAAATGGCGCTGAT
AAAAGGATAGATGTTTTAAGTACAGCCATTTACAGCAAACTGACAACACATGACCTTTTCCAGCTTGACCTGGCCTATGC
CCCACCCTATTCTACCCCGAAAGATGCCGTAGCCAGACTGGGAATGGTTTCCCAGAAGAAATTCAAGTAA

Upstream 100 bases:

>100_bases
TACTAATTGTTTCTATATATATTGATATAATGATATTAAATATAAAAGTTTTTTAATCTGGTTGATTTTCCAAAAATATT
AAAAAAAGGGTGAGGTTATA

Downstream 100 bases:

>100_bases
TATCAGGCCTATTATAAGAAAGGTTAATATAAACACAATTAAATCAGTTATTAAAAACCCTGCCGGTAACCATGGTACCA
GCAGGGTATTTACGTCCTCT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKIAIIGGVAAGTSAAAKAHRENPEAEIILFEKDENISYAGCGLPYYISGVTDSRQKVVINTPEAFTKKYKVEVRTGHRV
DEIIPDKKLIRYRNLKNNRDGEYRYDKLIITTGASPVIPPIPGIKLNNILTLRTINHADMIKNILNKNKPERVSIIGAGL
IGLEMAESFSKLGLKVTVIEKLPQVLPQFSPEMAQIVGAHLKENGVDLLLKDGVVKFTGDNSVEKVITESGQEIKTDLVL
VSVGIRPNVELARKAGIKIGPTGAIAVNNKMQTSLSDIYAAGDCAESTDLVSGKSIWAPLGSTANKQGRVAGENAAGGNN
RHDGVLKTAITKVFDLTVARTGLSEKEASEAGFDPIGVKIKAVNHAGYYPGLDKLHIKGVFDKKTKRIIGAEVIGKNGAD
KRIDVLSTAIYSKLTTHDLFQLDLAYAPPYSTPKDAVARLGMVSQKKFK

Sequences:

>Translated_449_residues
MKIAIIGGVAAGTSAAAKAHRENPEAEIILFEKDENISYAGCGLPYYISGVTDSRQKVVINTPEAFTKKYKVEVRTGHRV
DEIIPDKKLIRYRNLKNNRDGEYRYDKLIITTGASPVIPPIPGIKLNNILTLRTINHADMIKNILNKNKPERVSIIGAGL
IGLEMAESFSKLGLKVTVIEKLPQVLPQFSPEMAQIVGAHLKENGVDLLLKDGVVKFTGDNSVEKVITESGQEIKTDLVL
VSVGIRPNVELARKAGIKIGPTGAIAVNNKMQTSLSDIYAAGDCAESTDLVSGKSIWAPLGSTANKQGRVAGENAAGGNN
RHDGVLKTAITKVFDLTVARTGLSEKEASEAGFDPIGVKIKAVNHAGYYPGLDKLHIKGVFDKKTKRIIGAEVIGKNGAD
KRIDVLSTAIYSKLTTHDLFQLDLAYAPPYSTPKDAVARLGMVSQKKFK
>Mature_449_residues
MKIAIIGGVAAGTSAAAKAHRENPEAEIILFEKDENISYAGCGLPYYISGVTDSRQKVVINTPEAFTKKYKVEVRTGHRV
DEIIPDKKLIRYRNLKNNRDGEYRYDKLIITTGASPVIPPIPGIKLNNILTLRTINHADMIKNILNKNKPERVSIIGAGL
IGLEMAESFSKLGLKVTVIEKLPQVLPQFSPEMAQIVGAHLKENGVDLLLKDGVVKFTGDNSVEKVITESGQEIKTDLVL
VSVGIRPNVELARKAGIKIGPTGAIAVNNKMQTSLSDIYAAGDCAESTDLVSGKSIWAPLGSTANKQGRVAGENAAGGNN
RHDGVLKTAITKVFDLTVARTGLSEKEASEAGFDPIGVKIKAVNHAGYYPGLDKLHIKGVFDKKTKRIIGAEVIGKNGAD
KRIDVLSTAIYSKLTTHDLFQLDLAYAPPYSTPKDAVARLGMVSQKKFK

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=382, Percent_Identity=24.0837696335079, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI21389617, Length=382, Percent_Identity=24.0837696335079, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI65787454, Length=382, Percent_Identity=24.0837696335079, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI91199540, Length=335, Percent_Identity=26.5671641791045, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI22202629, Length=260, Percent_Identity=28.4615384615385, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4757732, Length=260, Percent_Identity=28.4615384615385, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1789065, Length=285, Percent_Identity=29.8245614035088, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1789765, Length=327, Percent_Identity=29.6636085626911, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786307, Length=309, Percent_Identity=28.1553398058252, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788892, Length=287, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87081717, Length=322, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082354, Length=300, Percent_Identity=25, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17559934, Length=181, Percent_Identity=34.2541436464088, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32565766, Length=302, Percent_Identity=25.4966887417219, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321091, Length=306, Percent_Identity=28.7581699346405, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24585130, Length=326, Percent_Identity=24.8466257668712, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24639257, Length=327, Percent_Identity=25.9938837920489, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281359715, Length=330, Percent_Identity=26.3636363636364, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281359713, Length=330, Percent_Identity=26.3636363636364, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639250, Length=330, Percent_Identity=26.3636363636364, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI18543267, Length=330, Percent_Identity=26.3636363636364, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639252, Length=330, Percent_Identity=26.3636363636364, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21358499, Length=307, Percent_Identity=28.6644951140065, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640553, Length=335, Percent_Identity=26.2686567164179, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640549, Length=335, Percent_Identity=26.2686567164179, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28573993, Length=231, Percent_Identity=25.1082251082251, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24581020, Length=231, Percent_Identity=25.1082251082251, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24640551, Length=335, Percent_Identity=26.2686567164179, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 48446; Mature: 48446

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIIGGVAAGTSAAAKAHRENPEAEIILFEKDENISYAGCGLPYYISGVTDSRQKVVI
CEEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCEEEECCCCCCCEEEE
NTPEAFTKKYKVEVRTGHRVDEIIPDKKLIRYRNLKNNRDGEYRYDKLIITTGASPVIPP
ECCHHHCEEEEEEEECCCCHHHHCCCHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCC
IPGIKLNNILTLRTINHADMIKNILNKNKPERVSIIGAGLIGLEMAESFSKLGLKVTVIE
CCCCEECCEEEEEECCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCEEEEHHH
KLPQVLPQFSPEMAQIVGAHLKENGVDLLLKDGVVKFTGDNSVEKVITESGQEIKTDLVL
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCEEEECCCCHHHHHHHCCCCCEEEEEEE
VSVGIRPNVELARKAGIKIGPTGAIAVNNKMQTSLSDIYAAGDCAESTDLVSGKSIWAPL
EEECCCCCHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCC
GSTANKQGRVAGENAAGGNNRHDGVLKTAITKVFDLTVARTGLSEKEASEAGFDPIGVKI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEE
KAVNHAGYYPGLDKLHIKGVFDKKTKRIIGAEVIGKNGADKRIDVLSTAIYSKLTTHDLF
EEEECCCCCCCCCCEEEEEECCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCHHE
QLDLAYAPPYSTPKDAVARLGMVSQKKFK
EEEEEECCCCCCHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MKIAIIGGVAAGTSAAAKAHRENPEAEIILFEKDENISYAGCGLPYYISGVTDSRQKVVI
CEEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCEEEECCCCCCCEEEE
NTPEAFTKKYKVEVRTGHRVDEIIPDKKLIRYRNLKNNRDGEYRYDKLIITTGASPVIPP
ECCHHHCEEEEEEEECCCCHHHHCCCHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCC
IPGIKLNNILTLRTINHADMIKNILNKNKPERVSIIGAGLIGLEMAESFSKLGLKVTVIE
CCCCEECCEEEEEECCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCEEEEHHH
KLPQVLPQFSPEMAQIVGAHLKENGVDLLLKDGVVKFTGDNSVEKVITESGQEIKTDLVL
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCEEEECCCCHHHHHHHCCCCCEEEEEEE
VSVGIRPNVELARKAGIKIGPTGAIAVNNKMQTSLSDIYAAGDCAESTDLVSGKSIWAPL
EEECCCCCHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCC
GSTANKQGRVAGENAAGGNNRHDGVLKTAITKVFDLTVARTGLSEKEASEAGFDPIGVKI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEE
KAVNHAGYYPGLDKLHIKGVFDKKTKRIIGAEVIGKNGADKRIDVLSTAIYSKLTTHDLF
EEEECCCCCCCCCCEEEEEECCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCHHE
QLDLAYAPPYSTPKDAVARLGMVSQKKFK
EEEEEECCCCCCHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA