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The map label for this gene is yajL [H]

Identifier: 220931968

GI number: 220931968

Start: 1222917

End: 1223462

Strand: Direct

Name: yajL [H]

Synonym: Hore_11290

Alternate gene names: 220931968

Gene position: 1222917-1223462 (Clockwise)

Preceding gene: 220931967

Following gene: 220931969

Centisome position: 47.43

GC content: 39.38

Gene sequence:

>546_bases
ATGAAAATATTAATTCCACTGGCTGAAGGTTTTGAAGAGATAGAAGCTATTACCAGTATAGACGTTCTCAGGAGGGCCGG
GATAGAGGTAATAACATCTTCTTTAACTGAATCAACTGAAGTTATGGGTTCCCATGATGTGAAAGTTACTGCCGATACTA
CCCTTGATAAGGTTTCTGTTGATAATCTAGATGGGATTCTTTTACCGGGGGGGATGCCGGGTTCAGCTAATTTAAAGGAT
GACATACGAATAATCAAACTAATTAAGAGATTAAATAAAAAATCCGGGCTGATTGCTGCTATCTGTGCTGCTCCCATCGT
CCTTGAAAAAGCCGGTGTTATAAAAGAAAAAAGGGCGACCAGTTATCCGGGTTTTGATAAAGAGATGAAGACCTGTAATT
ATCAAGAAAATAGAGTAGTGGTAGATGGAAATATAATTACCGGACGGGGTCCCGGGGTGGCTATGGAATTTGCCCTGACT
GTGGTTAATTATCTTACTAGCGAAGATATGGTTAAAGAACTTTCGGAAAAAATGATGGTTGAATAA

Upstream 100 bases:

>100_bases
CATACTTTATATTTTGGAGAGATACTGGGTTGTTATTTTGATAAAGATATTTAAATAATATAAGATATTTTTATAAATGA
CTGTAAGGAGGTAGAAGCAT

Downstream 100 bases:

>100_bases
TAATTTATGAGAACATTCAATAACATATGTTTTATTGTAAATTAATCTAATTTTATAAAAATAAAACTTGATTTTAACAT
TTGTGAAGTTAAAAAAAGGT

Product: DJ-1 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKILIPLAEGFEEIEAITSIDVLRRAGIEVITSSLTESTEVMGSHDVKVTADTTLDKVSVDNLDGILLPGGMPGSANLKD
DIRIIKLIKRLNKKSGLIAAICAAPIVLEKAGVIKEKRATSYPGFDKEMKTCNYQENRVVVDGNIITGRGPGVAMEFALT
VVNYLTSEDMVKELSEKMMVE

Sequences:

>Translated_181_residues
MKILIPLAEGFEEIEAITSIDVLRRAGIEVITSSLTESTEVMGSHDVKVTADTTLDKVSVDNLDGILLPGGMPGSANLKD
DIRIIKLIKRLNKKSGLIAAICAAPIVLEKAGVIKEKRATSYPGFDKEMKTCNYQENRVVVDGNIITGRGPGVAMEFALT
VVNYLTSEDMVKELSEKMMVE
>Mature_181_residues
MKILIPLAEGFEEIEAITSIDVLRRAGIEVITSSLTESTEVMGSHDVKVTADTTLDKVSVDNLDGILLPGGMPGSANLKD
DIRIIKLIKRLNKKSGLIAAICAAPIVLEKAGVIKEKRATSYPGFDKEMKTCNYQENRVVVDGNIITGRGPGVAMEFALT
VVNYLTSEDMVKELSEKMMVE

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=184, Percent_Identity=35.3260869565217, Blast_Score=110, Evalue=5e-25,
Organism=Homo sapiens, GI31543380, Length=184, Percent_Identity=35.3260869565217, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI87081736, Length=182, Percent_Identity=31.8681318681319, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082219, Length=154, Percent_Identity=29.8701298701299, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17531319, Length=181, Percent_Identity=38.6740331491713, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17558714, Length=180, Percent_Identity=36.1111111111111, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571932, Length=179, Percent_Identity=42.4581005586592, Blast_Score=136, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24653499, Length=179, Percent_Identity=39.6648044692737, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19626; Mature: 19626

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIPLAEGFEEIEAITSIDVLRRAGIEVITSSLTESTEVMGSHDVKVTADTTLDKVSV
CEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEC
DNLDGILLPGGMPGSANLKDDIRIIKLIKRLNKKSGLIAAICAAPIVLEKAGVIKEKRAT
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCC
SYPGFDKEMKTCNYQENRVVVDGNIITGRGPGVAMEFALTVVNYLTSEDMVKELSEKMMV
CCCCCCCHHHCCCCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCC
E
C
>Mature Secondary Structure
MKILIPLAEGFEEIEAITSIDVLRRAGIEVITSSLTESTEVMGSHDVKVTADTTLDKVSV
CEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEC
DNLDGILLPGGMPGSANLKDDIRIIKLIKRLNKKSGLIAAICAAPIVLEKAGVIKEKRAT
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCC
SYPGFDKEMKTCNYQENRVVVDGNIITGRGPGVAMEFALTVVNYLTSEDMVKELSEKMMV
CCCCCCCHHHCCCCCCCEEEECCEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]