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The map label for this gene is trkH [H]

Identifier: 220931903

GI number: 220931903

Start: 1150163

End: 1151596

Strand: Direct

Name: trkH [H]

Synonym: Hore_10610

Alternate gene names: 220931903

Gene position: 1150163-1151596 (Clockwise)

Preceding gene: 220931902

Following gene: 220931904

Centisome position: 44.61

GC content: 37.45

Gene sequence:

>1434_bases
ATGAATTATAAAGCAATACTAAATATTCTGGGGACATTATTGATAATAGTGGCTGCGGCCATGATACTTCCTGTTCTTGT
TGGGTTATATTACAGGGAAAAGGATATCTTTGCCTTTATAATTACATCTGGAATTACCTATTTGAGTGGGAAATTATTAA
AAAAGTGCACATATGAGGGAAAGGGTTTACAGTATAAGGATGGTTTTGTTGTAGTTACCCTGGGATGGTTTTTGGTATCT
ATTTACGGGGCCCTGCCCTTTTTAATCTCAGGTGTTTTTAAAAACCCAATTGATGCTTTTTTTGAATCTGTATCTGGTTT
TACCACAACAGGAGCAACGGTGATAATGTCTCTGGAAAGTGTCAGTAAAACCGTTTTATTCTGGAGGAGTTTAACCCACT
GGTTGGGTGGTATGGGAATTATTGTGATGACAATGGCAATACTGCCTGAGCTGGCAGGTAATATGCATCTATTTAAGGCT
GAAGTTCCAGGTCCGCTTCACAACAGAATTCAGCCCCGAATTCAGGATACAGCCAAAACGCTGTGGCTGTTATATTTTTT
TATAACAATATGTGAAATTATTTTACTGTGGATATCGGGGGTGCCTTTCTTTGAGTCAATAATTCATTCTTTTGGAACTG
TCTCTACAGGAGGGTTTTCATCCCGGGCTTTAAGTGTCAAGGCCTATAACAGCCTGTTGGTTGATACGATAGTTACTTTT
TTTATGTTTGTGGCCGGTACCAACTTTAATTTGATTTATGATTTGTTCAGAGGGAAAATAAGGACGTTTATAAAAGATGA
AGAATTCAGGTTTTATATCTGGATACTGCTTATTGCTATTTTTCTTGTTTCAATTAATTTAATTTTTAATGTTTATGATA
ATCCTAATGATGCAATCCGATATGCTTCATTCCAGGTGGTTTCCATATCGAGCACTACTGGATATGCTACTGTTGACTAT
GATACCTGGCCTCCTTTTAGCCGCTGGATTTTATTGATATTGATGTTTATCGGGGGAAGTGCCGGGTCAACTGCCGGGGG
AATAAAGGTAATTCGAATTAAGGTATTGTTTAAAAAAGGGTTACAGGAACTTTACTATTTACTCCACCCCCGGGCCATTA
AAAAAATAAAAATTAATAAAATGGTTGTGTCTGAAAGGGTTTCAACAAGTATTCTCGGGTTTTTTTTTCTGTATATTATG
GTTTTTGTAATGGTTACCGTAGTCCTGACCTACTTTGGTATAGATTTGATCAGTGCTATATCAGCAGTGGCTGCTACTCT
GGGAAATATAGGACCTGGTCTGGAGCTGGTGGGACCGTTAAATTCATATTTACCATTCCCCGATTCTGCTAAATTATTAT
TATCCTTCTGTATGATGTTGGGGAGACTTGAAATCTATACAATCCTGGTGTTTATGTTTATGGACTGGAGGTAA

Upstream 100 bases:

>100_bases
ATTCTCTTATTATATATAGAGTTTATTGTTGTATTCCACCCCTCATATCTATTGTATCTTGAACATAATTATAGTTTAGA
AAATTATGGGGTGGAATTAA

Downstream 100 bases:

>100_bases
AATATAACATCAGAAAGTTATGTAAACTTTCTCTTGAAATTTTTATATATTTTGGTATAATCAAAAAAGCCAGTATAGGT
CGGTTTTTGTCTTATTTTTT

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MNYKAILNILGTLLIIVAAAMILPVLVGLYYREKDIFAFIITSGITYLSGKLLKKCTYEGKGLQYKDGFVVVTLGWFLVS
IYGALPFLISGVFKNPIDAFFESVSGFTTTGATVIMSLESVSKTVLFWRSLTHWLGGMGIIVMTMAILPELAGNMHLFKA
EVPGPLHNRIQPRIQDTAKTLWLLYFFITICEIILLWISGVPFFESIIHSFGTVSTGGFSSRALSVKAYNSLLVDTIVTF
FMFVAGTNFNLIYDLFRGKIRTFIKDEEFRFYIWILLIAIFLVSINLIFNVYDNPNDAIRYASFQVVSISSTTGYATVDY
DTWPPFSRWILLILMFIGGSAGSTAGGIKVIRIKVLFKKGLQELYYLLHPRAIKKIKINKMVVSERVSTSILGFFFLYIM
VFVMVTVVLTYFGIDLISAISAVAATLGNIGPGLELVGPLNSYLPFPDSAKLLLSFCMMLGRLEIYTILVFMFMDWR

Sequences:

>Translated_477_residues
MNYKAILNILGTLLIIVAAAMILPVLVGLYYREKDIFAFIITSGITYLSGKLLKKCTYEGKGLQYKDGFVVVTLGWFLVS
IYGALPFLISGVFKNPIDAFFESVSGFTTTGATVIMSLESVSKTVLFWRSLTHWLGGMGIIVMTMAILPELAGNMHLFKA
EVPGPLHNRIQPRIQDTAKTLWLLYFFITICEIILLWISGVPFFESIIHSFGTVSTGGFSSRALSVKAYNSLLVDTIVTF
FMFVAGTNFNLIYDLFRGKIRTFIKDEEFRFYIWILLIAIFLVSINLIFNVYDNPNDAIRYASFQVVSISSTTGYATVDY
DTWPPFSRWILLILMFIGGSAGSTAGGIKVIRIKVLFKKGLQELYYLLHPRAIKKIKINKMVVSERVSTSILGFFFLYIM
VFVMVTVVLTYFGIDLISAISAVAATLGNIGPGLELVGPLNSYLPFPDSAKLLLSFCMMLGRLEIYTILVFMFMDWR
>Mature_477_residues
MNYKAILNILGTLLIIVAAAMILPVLVGLYYREKDIFAFIITSGITYLSGKLLKKCTYEGKGLQYKDGFVVVTLGWFLVS
IYGALPFLISGVFKNPIDAFFESVSGFTTTGATVIMSLESVSKTVLFWRSLTHWLGGMGIIVMTMAILPELAGNMHLFKA
EVPGPLHNRIQPRIQDTAKTLWLLYFFITICEIILLWISGVPFFESIIHSFGTVSTGGFSSRALSVKAYNSLLVDTIVTF
FMFVAGTNFNLIYDLFRGKIRTFIKDEEFRFYIWILLIAIFLVSINLIFNVYDNPNDAIRYASFQVVSISSTTGYATVDY
DTWPPFSRWILLILMFIGGSAGSTAGGIKVIRIKVLFKKGLQELYYLLHPRAIKKIKINKMVVSERVSTSILGFFFLYIM
VFVMVTVVLTYFGIDLISAISAVAATLGNIGPGLELVGPLNSYLPFPDSAKLLLSFCMMLGRLEIYTILVFMFMDWR

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=487, Percent_Identity=41.0677618069815, Blast_Score=308, Evalue=3e-85,
Organism=Escherichia coli, GI1787626, Length=490, Percent_Identity=35.5102040816327, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53511; Mature: 53511

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKAILNILGTLLIIVAAAMILPVLVGLYYREKDIFAFIITSGITYLSGKLLKKCTYEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHCCCC
KGLQYKDGFVVVTLGWFLVSIYGALPFLISGVFKNPIDAFFESVSGFTTTGATVIMSLES
CCCEEECCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHH
VSKTVLFWRSLTHWLGGMGIIVMTMAILPELAGNMHLFKAEVPGPLHNRIQPRIQDTAKT
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHHHHHHH
LWLLYFFITICEIILLWISGVPFFESIIHSFGTVSTGGFSSRALSVKAYNSLLVDTIVTF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHH
FMFVAGTNFNLIYDLFRGKIRTFIKDEEFRFYIWILLIAIFLVSINLIFNVYDNPNDAIR
HHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHE
YASFQVVSISSTTGYATVDYDTWPPFSRWILLILMFIGGSAGSTAGGIKVIRIKVLFKKG
EEEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHH
LQELYYLLHPRAIKKIKINKMVVSERVSTSILGFFFLYIMVFVMVTVVLTYFGIDLISAI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAVAATLGNIGPGLELVGPLNSYLPFPDSAKLLLSFCMMLGRLEIYTILVFMFMDWR
HHHHHHHHCCCCCCEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNYKAILNILGTLLIIVAAAMILPVLVGLYYREKDIFAFIITSGITYLSGKLLKKCTYEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHCCCC
KGLQYKDGFVVVTLGWFLVSIYGALPFLISGVFKNPIDAFFESVSGFTTTGATVIMSLES
CCCEEECCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHH
VSKTVLFWRSLTHWLGGMGIIVMTMAILPELAGNMHLFKAEVPGPLHNRIQPRIQDTAKT
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHHHHHHH
LWLLYFFITICEIILLWISGVPFFESIIHSFGTVSTGGFSSRALSVKAYNSLLVDTIVTF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHH
FMFVAGTNFNLIYDLFRGKIRTFIKDEEFRFYIWILLIAIFLVSINLIFNVYDNPNDAIR
HHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHE
YASFQVVSISSTTGYATVDYDTWPPFSRWILLILMFIGGSAGSTAGGIKVIRIKVLFKKG
EEEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHH
LQELYYLLHPRAIKKIKINKMVVSERVSTSILGFFFLYIMVFVMVTVVLTYFGIDLISAI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAVAATLGNIGPGLELVGPLNSYLPFPDSAKLLLSFCMMLGRLEIYTILVFMFMDWR
HHHHHHHHCCCCCCEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]