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The map label for this gene is gpsA

Identifier: 220931897

GI number: 220931897

Start: 1143952

End: 1144977

Strand: Direct

Name: gpsA

Synonym: Hore_10550

Alternate gene names: 220931897

Gene position: 1143952-1144977 (Clockwise)

Preceding gene: 220931896

Following gene: 220931898

Centisome position: 44.37

GC content: 39.77

Gene sequence:

>1026_bases
ATGTCAGATAGGATAAGTATTATCGGTGGAGGTAGCTGGGGGACTGCTATTGCCTATTTGTTGGCCATCAATGGTAAAAA
AGTATTAATGTATGTCAGAGATAATAATCAGAAGGATTCAATAAATAAAAAAAGGGTAAATAATAAATATTTTCCTGATC
ATCAACTCCCTGAAGGGATTGAGGCCACCACAGATATTAAAGAGGTAGTTTCTTTCTCAAATATTGTATTTCTGGCAGTA
CCTACCCATGCTACCAGGGCTGTTATGAAAAAAATAAATCATCTTTTAAATGAAGAACAGATCCTTGTTTCTACAGCAAA
AGGAATTGAAGAGGTCAATTTTTTACGTAATTCCCAGATAATCAAAGAATACTGTAACAATAAAATCGCCGTTTTATCGG
GTCCGACCCATGCTGAAGAGGTTATAGATGGTCTGCCAACCGCTGTAGTGGTAGCCTCCCGGGACAAAGAAGTTGCAGAA
TCCATTCAGGATATCATGATGTCATCAACCTTCAGGGTATATACAAATCCTGATGTAGTCGGAGTAGAAATGGGTGGGGC
TGTTAAAAATATAATTGCAGTGGCTGCTGGCATCGCTGATGGCCTTGGGTATGGTGATAATACCATGGCTGCCCTGATTA
CAAGGGGATTACATGAGATGAGTCGTCTCGGTGTTCATTTTGGAGGAAAATTACTTACTTTTGCCGGTCTGGCCGGTATG
GGGGACCTGGTTGTTACCTGTACCAGTAATCATAGCAGGAACAGGAGATTTGGTATAAAAGTAGGAAAGGGTATGAATAC
GGAAGAGGCCCTGTCAAGTGTAAATCAGGTTGTCGAAGGGGTCAGGACTACCAGGGCGGTTTATGATTGGTATCAGGGTA
AAAAACTTAATTTTGAATTACCTATAACCAGTCAAATTTATCAGGTATTATTCAATGATAAAAATCCCCTTGATGCGGTT
AATGAATTAATGTTAAGGGGGCCAAAACATGAAATTGAAGAAGTTGTTGATGATGTGAACTGGTAG

Upstream 100 bases:

>100_bases
ATATTGATTTTATATAGACATAAAGGTAATATTAAACGGCTTCTTTCAGGAATCGAAAACAGAATGAAATGGCCTCCCAA
GATTGAAGGGAGTGATAGTG

Downstream 100 bases:

>100_bases
TTGTCCAGATAAAAAGTTAACATAGGTTTGTCAAAACAGGGTAAACAACCCTGTTTTTTTTATGTTTAATGGTGGCATAT
TTTAGACTTGCACTCATATA

Product: glycerol-3-phosphate dehydrogenase (NAD(P)(+))

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSDRISIIGGGSWGTAIAYLLAINGKKVLMYVRDNNQKDSINKKRVNNKYFPDHQLPEGIEATTDIKEVVSFSNIVFLAV
PTHATRAVMKKINHLLNEEQILVSTAKGIEEVNFLRNSQIIKEYCNNKIAVLSGPTHAEEVIDGLPTAVVVASRDKEVAE
SIQDIMMSSTFRVYTNPDVVGVEMGGAVKNIIAVAAGIADGLGYGDNTMAALITRGLHEMSRLGVHFGGKLLTFAGLAGM
GDLVVTCTSNHSRNRRFGIKVGKGMNTEEALSSVNQVVEGVRTTRAVYDWYQGKKLNFELPITSQIYQVLFNDKNPLDAV
NELMLRGPKHEIEEVVDDVNW

Sequences:

>Translated_341_residues
MSDRISIIGGGSWGTAIAYLLAINGKKVLMYVRDNNQKDSINKKRVNNKYFPDHQLPEGIEATTDIKEVVSFSNIVFLAV
PTHATRAVMKKINHLLNEEQILVSTAKGIEEVNFLRNSQIIKEYCNNKIAVLSGPTHAEEVIDGLPTAVVVASRDKEVAE
SIQDIMMSSTFRVYTNPDVVGVEMGGAVKNIIAVAAGIADGLGYGDNTMAALITRGLHEMSRLGVHFGGKLLTFAGLAGM
GDLVVTCTSNHSRNRRFGIKVGKGMNTEEALSSVNQVVEGVRTTRAVYDWYQGKKLNFELPITSQIYQVLFNDKNPLDAV
NELMLRGPKHEIEEVVDDVNW
>Mature_340_residues
SDRISIIGGGSWGTAIAYLLAINGKKVLMYVRDNNQKDSINKKRVNNKYFPDHQLPEGIEATTDIKEVVSFSNIVFLAVP
THATRAVMKKINHLLNEEQILVSTAKGIEEVNFLRNSQIIKEYCNNKIAVLSGPTHAEEVIDGLPTAVVVASRDKEVAES
IQDIMMSSTFRVYTNPDVVGVEMGGAVKNIIAVAAGIADGLGYGDNTMAALITRGLHEMSRLGVHFGGKLLTFAGLAGMG
DLVVTCTSNHSRNRRFGIKVGKGMNTEEALSSVNQVVEGVRTTRAVYDWYQGKKLNFELPITSQIYQVLFNDKNPLDAVN
ELMLRGPKHEIEEVVDDVNW

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=349, Percent_Identity=29.2263610315186, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI24307999, Length=347, Percent_Identity=29.971181556196, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1790037, Length=330, Percent_Identity=41.8181818181818, Blast_Score=275, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI32564399, Length=349, Percent_Identity=31.5186246418338, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI193210136, Length=358, Percent_Identity=30.7262569832402, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32564403, Length=358, Percent_Identity=30.7262569832402, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17507425, Length=334, Percent_Identity=27.8443113772455, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI193210134, Length=346, Percent_Identity=28.9017341040462, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324513, Length=342, Percent_Identity=28.0701754385965, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320181, Length=356, Percent_Identity=26.4044943820225, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI22026922, Length=343, Percent_Identity=30.0291545189504, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI17136200, Length=354, Percent_Identity=30.225988700565, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI17136204, Length=354, Percent_Identity=30.225988700565, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI17136202, Length=354, Percent_Identity=30.225988700565, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI45551945, Length=261, Percent_Identity=26.8199233716475, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281362270, Length=261, Percent_Identity=26.8199233716475, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648969, Length=251, Percent_Identity=25.8964143426295, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_HALOH (B8CWZ1)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508805.1
- ProteinModelPortal:   B8CWZ1
- SMR:   B8CWZ1
- GeneID:   7314643
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_10550
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 37435; Mature: 37304

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 189-189 BINDING 107-107 BINDING 107-107 BINDING 138-138 BINDING 253-253 BINDING 279-279

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRISIIGGGSWGTAIAYLLAINGKKVLMYVRDNNQKDSINKKRVNNKYFPDHQLPEGI
CCCCEEEEECCCHHHHHHHHHEECCCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCC
EATTDIKEVVSFSNIVFLAVPTHATRAVMKKINHLLNEEQILVSTAKGIEEVNFLRNSQI
CHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHH
IKEYCNNKIAVLSGPTHAEEVIDGLPTAVVVASRDKEVAESIQDIMMSSTFRVYTNPDVV
HHHHHCCEEEEEECCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCEE
GVEMGGAVKNIIAVAAGIADGLGYGDNTMAALITRGLHEMSRLGVHFGGKLLTFAGLAGM
EEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
GDLVVTCTSNHSRNRRFGIKVGKGMNTEEALSSVNQVVEGVRTTRAVYDWYQGKKLNFEL
CCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
PITSQIYQVLFNDKNPLDAVNELMLRGPKHEIEEVVDDVNW
CHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SDRISIIGGGSWGTAIAYLLAINGKKVLMYVRDNNQKDSINKKRVNNKYFPDHQLPEGI
CCCEEEEECCCHHHHHHHHHEECCCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCC
EATTDIKEVVSFSNIVFLAVPTHATRAVMKKINHLLNEEQILVSTAKGIEEVNFLRNSQI
CHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHH
IKEYCNNKIAVLSGPTHAEEVIDGLPTAVVVASRDKEVAESIQDIMMSSTFRVYTNPDVV
HHHHHCCEEEEEECCCHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCEE
GVEMGGAVKNIIAVAAGIADGLGYGDNTMAALITRGLHEMSRLGVHFGGKLLTFAGLAGM
EEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
GDLVVTCTSNHSRNRRFGIKVGKGMNTEEALSSVNQVVEGVRTTRAVYDWYQGKKLNFEL
CCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
PITSQIYQVLFNDKNPLDAVNELMLRGPKHEIEEVVDDVNW
CHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA