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The map label for this gene is aroA [H]

Identifier: 220931880

GI number: 220931880

Start: 1124759

End: 1126051

Strand: Direct

Name: aroA [H]

Synonym: Hore_10370

Alternate gene names: 220931880

Gene position: 1124759-1126051 (Clockwise)

Preceding gene: 220931879

Following gene: 220931881

Centisome position: 43.63

GC content: 40.76

Gene sequence:

>1293_bases
GTGGAACTCAAAATAAAAAAGAGTAATCCCCTTAAGGGTGAAATAAATATTCCAGGTGATAAATCTATCTCACATCGTTC
GGTGATATTTACCTCTCTTGCAGAAGGAAGAAGTTTAATCAGGGGGTTTCTGGAAAGTGAGGACTGTTTAAATACCCTCA
GGGCTTTCCAGATGATGGGAGTTAATATTGAGAAGATAAAGCCTGGAGAATATATAGTAAATGGGGTTGGCCTTTATGGT
TTAAAAGAGCCTGGTGATGTCATTGACTGCGGTAATTCCGGAACTGGTATGAGGCTTTTATGTGGTCTTCTGGCTCCCCA
ACCTTTCTATAGTGTGTTGACAGGTGATAACTCTCTTCGAAATAGACCGATGGGAAGAGTGGTAAACCCTTTAAGACAGA
TGGGGGCCAGTATCTGGTGCCGTGATGGGGGGTATGCCCCTTTAAGCATTAAGGGGGAGAAACTTGAGGGAATTTCCTAC
ACTTTACCGGTTGCCAGTGCTCAGGTAAAATCCTCTCTGTTACTGGCAGGGTTGTATTCACAGGGAGATGTTTTTCTTAC
CGAACCAGGTCCCTCCCGGGACCATACCGAGAGAATGCTTAAGGGTTTTGGTGTAAAAGTTTATAAAAAAGGTAATTCTA
TAAAACTTCCCCATAGTGAGGACACTAAATTAACTCCCCAGGAGGTTTTAATACCCGGTGATATCTCTTCAGCTGCTTTT
TTTATTGTTGCTTCTTTAATAACACCGGGCAGTGAGATTCTCCTTAAAAATGTTGGTCTAAACCCGACCAGATGTGGTAT
AATTGATGTTGTAAGGCAGATGGGAGGGAACCTTGAATTGTTAAATGTAAGAGAGGTTAATGGGGAGAAATCAGCTGATA
TTTTAGTAAAATATAGTGAGTTAGAGGGTGTTCATATTGATGGAGATATTATACCGAGACTTATAGATGAAATACCGGTT
ATCGCAGTTCTGGCGTCCCAGGCCCGTGGGGAAACAGTTATTAGAGATGCTGCAGAATTAAAGGTTAAAGAGACTGATAG
AATCAAGGCTACCGTTACTGAACTCGGTAAATCAGGGGTTGATATTGAAGAATTACCTGATGGCATGGTTATTAAAGGCC
CCTGTTCTATTATAGGGGGAGTAAAATTAGAGAGCTATAAAGACCACAGAATAGCCATGTCCCTGGCTGTAGCTGGACTG
TTAGCTGAAGAACAGATTACTATTAAAAATAGTGAGTGTATTAACACATCTTTCCCGCAATTCAATAAACTATTACAGAA
ATTAATTCAATAA

Upstream 100 bases:

>100_bases
AAAATTAAGGTTTCACTAAGAAATAATGACGAAGAAGTACTTTATCGCTTTATGAAATCAGGGAGGCAGAGAAGAAAAGA
TTTAGAGAAGGTGATAACTG

Downstream 100 bases:

>100_bases
TACAGGTGATGAAGATGAAGAAAAACCTTGAGTATTTTTATGTACTTTTTTTAATTCCTTTTTTATGGGGTAGTACTTTT
TTGTTTACCAAGGTATGCCT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MELKIKKSNPLKGEINIPGDKSISHRSVIFTSLAEGRSLIRGFLESEDCLNTLRAFQMMGVNIEKIKPGEYIVNGVGLYG
LKEPGDVIDCGNSGTGMRLLCGLLAPQPFYSVLTGDNSLRNRPMGRVVNPLRQMGASIWCRDGGYAPLSIKGEKLEGISY
TLPVASAQVKSSLLLAGLYSQGDVFLTEPGPSRDHTERMLKGFGVKVYKKGNSIKLPHSEDTKLTPQEVLIPGDISSAAF
FIVASLITPGSEILLKNVGLNPTRCGIIDVVRQMGGNLELLNVREVNGEKSADILVKYSELEGVHIDGDIIPRLIDEIPV
IAVLASQARGETVIRDAAELKVKETDRIKATVTELGKSGVDIEELPDGMVIKGPCSIIGGVKLESYKDHRIAMSLAVAGL
LAEEQITIKNSECINTSFPQFNKLLQKLIQ

Sequences:

>Translated_430_residues
MELKIKKSNPLKGEINIPGDKSISHRSVIFTSLAEGRSLIRGFLESEDCLNTLRAFQMMGVNIEKIKPGEYIVNGVGLYG
LKEPGDVIDCGNSGTGMRLLCGLLAPQPFYSVLTGDNSLRNRPMGRVVNPLRQMGASIWCRDGGYAPLSIKGEKLEGISY
TLPVASAQVKSSLLLAGLYSQGDVFLTEPGPSRDHTERMLKGFGVKVYKKGNSIKLPHSEDTKLTPQEVLIPGDISSAAF
FIVASLITPGSEILLKNVGLNPTRCGIIDVVRQMGGNLELLNVREVNGEKSADILVKYSELEGVHIDGDIIPRLIDEIPV
IAVLASQARGETVIRDAAELKVKETDRIKATVTELGKSGVDIEELPDGMVIKGPCSIIGGVKLESYKDHRIAMSLAVAGL
LAEEQITIKNSECINTSFPQFNKLLQKLIQ
>Mature_430_residues
MELKIKKSNPLKGEINIPGDKSISHRSVIFTSLAEGRSLIRGFLESEDCLNTLRAFQMMGVNIEKIKPGEYIVNGVGLYG
LKEPGDVIDCGNSGTGMRLLCGLLAPQPFYSVLTGDNSLRNRPMGRVVNPLRQMGASIWCRDGGYAPLSIKGEKLEGISY
TLPVASAQVKSSLLLAGLYSQGDVFLTEPGPSRDHTERMLKGFGVKVYKKGNSIKLPHSEDTKLTPQEVLIPGDISSAAF
FIVASLITPGSEILLKNVGLNPTRCGIIDVVRQMGGNLELLNVREVNGEKSADILVKYSELEGVHIDGDIIPRLIDEIPV
IAVLASQARGETVIRDAAELKVKETDRIKATVTELGKSGVDIEELPDGMVIKGPCSIIGGVKLESYKDHRIAMSLAVAGL
LAEEQITIKNSECINTSFPQFNKLLQKLIQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=432, Percent_Identity=29.6296296296296, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320332, Length=471, Percent_Identity=27.1762208067941, Blast_Score=122, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46564; Mature: 46564

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKIKKSNPLKGEINIPGDKSISHRSVIFTSLAEGRSLIRGFLESEDCLNTLRAFQMMG
CCEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
VNIEKIKPGEYIVNGVGLYGLKEPGDVIDCGNSGTGMRLLCGLLAPQPFYSVLTGDNSLR
CCCEEECCCCEEEECEEEECCCCCCCEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCHHH
NRPMGRVVNPLRQMGASIWCRDGGYAPLSIKGEKLEGISYTLPVASAQVKSSLLLAGLYS
CCCHHHHHHHHHHCCCEEEECCCCCCEEEECCCEECCCEEECCCCHHHHHHHHHEEEECC
QGDVFLTEPGPSRDHTERMLKGFGVKVYKKGNSIKLPHSEDTKLTPQEVLIPGDISSAAF
CCCEEEECCCCCHHHHHHHHHHCCEEEEECCCEEECCCCCCCCCCHHHEEECCCCCHHHH
FIVASLITPGSEILLKNVGLNPTRCGIIDVVRQMGGNLELLNVREVNGEKSADILVKYSE
HHHHHHHCCCHHHHEECCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEC
LEGVHIDGDIIPRLIDEIPVIAVLASQARGETVIRDAAELKVKETDRIKATVTELGKSGV
CCCEEECHHHHHHHHHHCCEEEHHHHCCCCCHHHHHHHHCEECCCHHHHHHHHHHCCCCC
DIEELPDGMVIKGPCSIIGGVKLESYKDHRIAMSLAVAGLLAEEQITIKNSECINTSFPQ
CHHHCCCCCEEECCHHEECCCEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHH
FNKLLQKLIQ
HHHHHHHHHC
>Mature Secondary Structure
MELKIKKSNPLKGEINIPGDKSISHRSVIFTSLAEGRSLIRGFLESEDCLNTLRAFQMMG
CCEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
VNIEKIKPGEYIVNGVGLYGLKEPGDVIDCGNSGTGMRLLCGLLAPQPFYSVLTGDNSLR
CCCEEECCCCEEEECEEEECCCCCCCEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCHHH
NRPMGRVVNPLRQMGASIWCRDGGYAPLSIKGEKLEGISYTLPVASAQVKSSLLLAGLYS
CCCHHHHHHHHHHCCCEEEECCCCCCEEEECCCEECCCEEECCCCHHHHHHHHHEEEECC
QGDVFLTEPGPSRDHTERMLKGFGVKVYKKGNSIKLPHSEDTKLTPQEVLIPGDISSAAF
CCCEEEECCCCCHHHHHHHHHHCCEEEEECCCEEECCCCCCCCCCHHHEEECCCCCHHHH
FIVASLITPGSEILLKNVGLNPTRCGIIDVVRQMGGNLELLNVREVNGEKSADILVKYSE
HHHHHHHCCCHHHHEECCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEC
LEGVHIDGDIIPRLIDEIPVIAVLASQARGETVIRDAAELKVKETDRIKATVTELGKSGV
CCCEEECHHHHHHHHHHCCEEEHHHHCCCCCHHHHHHHHCEECCCHHHHHHHHHHCCCCC
DIEELPDGMVIKGPCSIIGGVKLESYKDHRIAMSLAVAGLLAEEQITIKNSECINTSFPQ
CHHHCCCCCEEECCHHEECCCEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHH
FNKLLQKLIQ
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA