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The map label for this gene is oxyS [H]

Identifier: 221230912

GI number: 221230912

Start: 3189244

End: 3190176

Strand: Reverse

Name: oxyS [H]

Synonym: MLBr_02663

Alternate gene names: 221230912

Gene position: 3190176-3189244 (Counterclockwise)

Preceding gene: 221230914

Following gene: 221230911

Centisome position: 97.62

GC content: 59.27

Gene sequence:

>933_bases
GTGCTCTTCCGTCAACTGGAGTACTTCGTCGCGGTAGCCCAGGAGCGGCACTTCGCCAGAGCGGCCGAAAGGTGCTACGT
TTCGCAACCTGCGCTCTCATCCGCGATCGCCAAACTCGAACGTGAGCTGAACGTCACACTGATTAACCGGGGGCACAGCT
TTGAGGGCCTAACGCCCGAAGGGGAGCGCCTGGTCGTGTGGGCCAAGCGTATTCTCGCCGAACACGATGCATTCAAGGCA
GAGGTGCATGCAGTGCGGTCCGGGATCACTGGTACGCTTCGATTAGGCACGGTGCCTACTGCCTCGACGACAGCGTCCCT
GGTCCTCTCGGCTTTTTGTTCGGAGCACCCATTGATAAAAGTGCAAATCTGCTCCCGACTGCCTGTCACTGAACTGCACC
GACGGCTGGGCGATTTTGAGCTCGATGCCGTCATCGTACACTCCGCGCCTGACGACACTCACGCTGTGGACCTGGTGCCG
CTTTACCATGAACATTACGTGTTGGTATCGCCGGCGGATATGTTGCCGCCTGGGGCGTCGGTGTTGGCATGGCCAGAAGC
CTCGCAGCTGCCGCTGGCTTTACTCACGCCCGACATGCGAGACCGCCAGCTTATTGATAGGGCCTTTGCTGGTCACGCGA
TCACTGCTACCCCGCAAGTAGAGACCGACTCTGTCGCTTCGTTATTCGCTCAAGTGGCGACTGGAAATTGGGCGTGCATT
GTTCCGCACACCTGGCTGTGGACGACGCCGATAGGCGCAGAGATCCGTGCGGTAGAAATGGTTGATCCGGTTCTGAAAGC
CGACGTCGCACTCGCCACCAACTCCGCCGGGCCAGGTTCTCCGGTAGCCCGTGCGCTCGTCGCATCCGCCAAGCAACTGG
CGTTGAACGAATTTTTTGAAGCTCAGTTAGCGGGAATCACTCGTAGACGCTGA

Upstream 100 bases:

>100_bases
TTAGAAATCTATTTGCGGTTGCTTCGAGTGGGTAGGTTGGATGGGCTGGTAGCGACGCGTTAGCCTCAGCGAGATTGGTA
CCCAAAGGGAGGAGGTACGG

Downstream 100 bases:

>100_bases
CCGATATTGCGGCATTGCGGCGTTCGTGGGTTTGAGGCGCGCGAGGCGTCCGTTTTTCACCTCCACGGTTGGATGCCACG
AGCTCGAAGTCAACGATTGA

Product: putative LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLFRQLEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTPEGERLVVWAKRILAEHDAFKA
EVHAVRSGITGTLRLGTVPTASTTASLVLSAFCSEHPLIKVQICSRLPVTELHRRLGDFELDAVIVHSAPDDTHAVDLVP
LYHEHYVLVSPADMLPPGASVLAWPEASQLPLALLTPDMRDRQLIDRAFAGHAITATPQVETDSVASLFAQVATGNWACI
VPHTWLWTTPIGAEIRAVEMVDPVLKADVALATNSAGPGSPVARALVASAKQLALNEFFEAQLAGITRRR

Sequences:

>Translated_310_residues
MLFRQLEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTPEGERLVVWAKRILAEHDAFKA
EVHAVRSGITGTLRLGTVPTASTTASLVLSAFCSEHPLIKVQICSRLPVTELHRRLGDFELDAVIVHSAPDDTHAVDLVP
LYHEHYVLVSPADMLPPGASVLAWPEASQLPLALLTPDMRDRQLIDRAFAGHAITATPQVETDSVASLFAQVATGNWACI
VPHTWLWTTPIGAEIRAVEMVDPVLKADVALATNSAGPGSPVARALVASAKQLALNEFFEAQLAGITRRR
>Mature_310_residues
MLFRQLEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTPEGERLVVWAKRILAEHDAFKA
EVHAVRSGITGTLRLGTVPTASTTASLVLSAFCSEHPLIKVQICSRLPVTELHRRLGDFELDAVIVHSAPDDTHAVDLVP
LYHEHYVLVSPADMLPPGASVLAWPEASQLPLALLTPDMRDRQLIDRAFAGHAITATPQVETDSVASLFAQVATGNWACI
VPHTWLWTTPIGAEIRAVEMVDPVLKADVALATNSAGPGSPVARALVASAKQLALNEFFEAQLAGITRRR

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=32.1285140562249, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=267, Percent_Identity=28.0898876404494, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790399, Length=102, Percent_Identity=42.156862745098, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367136, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=122, Percent_Identity=36.0655737704918, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788887, Length=174, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=22.9965156794425, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787530, Length=218, Percent_Identity=25.6880733944954, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787589, Length=163, Percent_Identity=29.4478527607362, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33722; Mature: 33722

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFRQLEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
GERLVVWAKRILAEHDAFKAEVHAVRSGITGTLRLGTVPTASTTASLVLSAFCSEHPLIK
CCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
VQICSRLPVTELHRRLGDFELDAVIVHSAPDDTHAVDLVPLYHEHYVLVSPADMLPPGAS
EEECCCCCHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEECCCEEEEECHHHCCCCCC
VLAWPEASQLPLALLTPDMRDRQLIDRAFAGHAITATPQVETDSVASLFAQVATGNWACI
EEECCCCCCCCEEEECCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHCCCEEEE
VPHTWLWTTPIGAEIRAVEMVDPVLKADVALATNSAGPGSPVARALVASAKQLALNEFFE
ECCCEEEECCCCCCEEEHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
AQLAGITRRR
HHHHHHHCCC
>Mature Secondary Structure
MLFRQLEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
GERLVVWAKRILAEHDAFKAEVHAVRSGITGTLRLGTVPTASTTASLVLSAFCSEHPLIK
CCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
VQICSRLPVTELHRRLGDFELDAVIVHSAPDDTHAVDLVPLYHEHYVLVSPADMLPPGAS
EEECCCCCHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEEEECCCEEEEECHHHCCCCCC
VLAWPEASQLPLALLTPDMRDRQLIDRAFAGHAITATPQVETDSVASLFAQVATGNWACI
EEECCCCCCCCEEEECCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHCCCEEEE
VPHTWLWTTPIGAEIRAVEMVDPVLKADVALATNSAGPGSPVARALVASAKQLALNEFFE
ECCCEEEECCCCCCEEEHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
AQLAGITRRR
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA