Click here to switch to the map view.

The map label for this gene is esxR

Identifier: 221230840

GI number: 221230840

Start: 3014056

End: 3014346

Strand: Reverse

Name: esxR

Synonym: MLBr_02531

Alternate gene names: 221230840

Gene position: 3014346-3014056 (Counterclockwise)

Preceding gene: 221230841

Following gene: 221230839

Centisome position: 92.24

GC content: 58.08

Gene sequence:

>291_bases
ATGACACAGATTATGTACAACTACCCGGCAATGTTGGACCACGCCGGGAATATGTCAGCCTGCGCCGGCGCTTTGCAGGG
GGTGGGCATCGACATCGCTGCCGAGCAAGCTGCGTTGCAAGCTTGCTGGGGGGGCGATACTGGGATTAGTTATCAGGCCT
GGCAGGTGCAGTGGAACCAGGCCACGGAAGAGATGGTGCGTGCCTACCATGCAATGGCCAACACTCACCAAAACAACACT
TTGGCTATGCTCACCCGCGACCAAGCTGAAGCCGCCAAATGGGGCGGCTAA

Upstream 100 bases:

>100_bases
CAGCAGAGACGTATGTGGCCACCGATGCTACGGCTGCGTCGACTTACACCACCGGGCTGTGATCCGACTACTAGACTAAA
AATAACCGAAAGGATTTGTT

Downstream 100 bases:

>100_bases
TCGTGCGGTCATGAAGGTCGATCCCAACGCCGTTGAGTTGACGGTCGATCACGCGTGGTTCATTGCGGAAGTCATTGGAG
CGGGTAGCTTCCCGTGGGTT

Product: putative cell surface protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MTQIMYNYPAMLDHAGNMSACAGALQGVGIDIAAEQAALQACWGGDTGISYQAWQVQWNQATEEMVRAYHAMANTHQNNT
LAMLTRDQAEAAKWGG

Sequences:

>Translated_96_residues
MTQIMYNYPAMLDHAGNMSACAGALQGVGIDIAAEQAALQACWGGDTGISYQAWQVQWNQATEEMVRAYHAMANTHQNNT
LAMLTRDQAEAAKWGG
>Mature_95_residues
TQIMYNYPAMLDHAGNMSACAGALQGVGIDIAAEQAALQACWGGDTGISYQAWQVQWNQATEEMVRAYHAMANTHQNNTL
AMLTRDQAEAAKWGG

Specific function: Unknown

COG id: COG4842

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ESXR_MYCLE (Q9CD33)

Other databases:

- EMBL:   AL583926
- PIR:   H87225
- RefSeq:   NP_302626.1
- ProteinModelPortal:   Q9CD33
- SMR:   Q9CD33
- EnsemblBacteria:   EBMYCT00000029289
- GeneID:   908479
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML2531
- NMPDR:   fig|272631.1.peg.1498
- Leproma:   ML2531
- GeneTree:   EBGT00050000016281
- HOGENOM:   HBG565735
- OMA:   SGYAGTM
- ProtClustDB:   CLSK790405
- BioCyc:   MLEP272631:ML2531-MONOMER
- InterPro:   IPR010310

Pfam domain/function: PF06013 WXG100

EC number: NA

Molecular weight: Translated: 10393; Mature: 10262

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
9.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQIMYNYPAMLDHAGNMSACAGALQGVGIDIAAEQAALQACWGGDTGISYQAWQVQWNQ
CCEEECCCCHHHCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCEEEEEEEHHH
ATEEMVRAYHAMANTHQNNTLAMLTRDQAEAAKWGG
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCC
>Mature Secondary Structure 
TQIMYNYPAMLDHAGNMSACAGALQGVGIDIAAEQAALQACWGGDTGISYQAWQVQWNQ
CEEECCCCHHHCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCEEEEEEEHHH
ATEEMVRAYHAMANTHQNNTLAMLTRDQAEAAKWGG
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002