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The map label for this gene is tyrA [H]

Identifier: 221230814

GI number: 221230814

Start: 2947033

End: 2948016

Strand: Reverse

Name: tyrA [H]

Synonym: MLBr_02472

Alternate gene names: 221230814

Gene position: 2948016-2947033 (Counterclockwise)

Preceding gene: 221230817

Following gene: 221230813

Centisome position: 90.21

GC content: 62.6

Gene sequence:

>984_bases
GTGTCAATCTTGGATGGTGGCTGGGACTGCGTCGGGCGACCGGTGTGCGTGCTTGGGCTGGGATTGATCGGCGGATCGAT
CATGCGGGCCACGGCGGAGGCCGGTCGTGAGGTTTTCGGCTATAATCGTTCAGTGAAAGGCGCGCAGAGCGCTCGGTCAG
ACGGTTTTGACGCCACTACCAAACTTGCTGACGCGTTAGTTCGCGCCGCCGATACCCACGCATTGATCGTGCTGGCTGTG
CCGATGCCGGCATTGCCGGCCATGCTCGCCCACATTCGCGAATTGGCGCCCAACTGTCCGCTCACTGATGTTACCAGCGT
CAAAACCGCGGTGCTCGACGCGGTTGTTTCGGTTGGTTTGCAGGCCCGCTTCGTCGGTGGTCACCCGATGACCGGCACTG
CGCAATCGGGTTGGGGCGCCGGACATGGCGGGTTGTTCAACAGGACTTCCTGGGTGCTTAGTGTAGACGACCATGTGGAC
CCCGCGGTGTGGTCAATGGTTATGACATTGGCGTTGGATTGCGGCGCGCTGGTATTACCGGCAAAATCCGACGAGCACGA
CGCCGCTGCAGCTGCCATTTCGCATATGCCGCACTTGCTCGCTGAAGCTTTGGCTGTAGCCGCCGCTGAGGTTCCGCTGG
CGTTCGCGGTGGCGGCAGGATCGTTCCGTGACGCCACCCGAGTAGCCGGAACCGCTCCGGACTTAGTGCGTGCGATGTGC
GAAGGAAACTCCGGCCAACTGCTGTCGTCCGTCGACCGGGTCATCGAGTTGCTTTGCCGTGCCCGCGACTCCCTGGCTTG
CAACAATTCAGTGGCTGAACTCGTCGAAGCGGGCCATGCCGCGCGCGCGCGTTACGACAGCTTCCCGCGCTCCGACATCG
TCACCGTCATCATCGGCGCGGAGAATTGGCGCGAAGACCTGGCGGCTGCAGGCCGAGCAGGTGGGGTGATCAGATCCGCT
CTGCCAAGCCTGGGTAGTCCATGA

Upstream 100 bases:

>100_bases
TTCTGCCCCCATGGGCGCTTACGCTAGTCGCCGACCGGGTCCCTTGACCAGATGACTGCTCGTGATCGACAGCACTTGGG
GCAACCACGACCCGCAAACT

Downstream 100 bases:

>100_bases
TAAACGCGTCGGCATCGACGATGGTGTTCCTGACCGGTGAACGCAACTTGATTCCGTCAAGGTGTATTGAGCTGGTGTAG
CTCACGGTGTCGGCTGCGAC

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSILDGGWDCVGRPVCVLGLGLIGGSIMRATAEAGREVFGYNRSVKGAQSARSDGFDATTKLADALVRAADTHALIVLAV
PMPALPAMLAHIRELAPNCPLTDVTSVKTAVLDAVVSVGLQARFVGGHPMTGTAQSGWGAGHGGLFNRTSWVLSVDDHVD
PAVWSMVMTLALDCGALVLPAKSDEHDAAAAAISHMPHLLAEALAVAAAEVPLAFAVAAGSFRDATRVAGTAPDLVRAMC
EGNSGQLLSSVDRVIELLCRARDSLACNNSVAELVEAGHAARARYDSFPRSDIVTVIIGAENWREDLAAAGRAGGVIRSA
LPSLGSP

Sequences:

>Translated_327_residues
MSILDGGWDCVGRPVCVLGLGLIGGSIMRATAEAGREVFGYNRSVKGAQSARSDGFDATTKLADALVRAADTHALIVLAV
PMPALPAMLAHIRELAPNCPLTDVTSVKTAVLDAVVSVGLQARFVGGHPMTGTAQSGWGAGHGGLFNRTSWVLSVDDHVD
PAVWSMVMTLALDCGALVLPAKSDEHDAAAAAISHMPHLLAEALAVAAAEVPLAFAVAAGSFRDATRVAGTAPDLVRAMC
EGNSGQLLSSVDRVIELLCRARDSLACNNSVAELVEAGHAARARYDSFPRSDIVTVIIGAENWREDLAAAGRAGGVIRSA
LPSLGSP
>Mature_326_residues
SILDGGWDCVGRPVCVLGLGLIGGSIMRATAEAGREVFGYNRSVKGAQSARSDGFDATTKLADALVRAADTHALIVLAVP
MPALPAMLAHIRELAPNCPLTDVTSVKTAVLDAVVSVGLQARFVGGHPMTGTAQSGWGAGHGGLFNRTSWVLSVDDHVDP
AVWSMVMTLALDCGALVLPAKSDEHDAAAAAISHMPHLLAEALAVAAAEVPLAFAVAAGSFRDATRVAGTAPDLVRAMCE
GNSGQLLSSVDRVIELLCRARDSLACNNSVAELVEAGHAARARYDSFPRSDIVTVIIGAENWREDLAAAGRAGGVIRSAL
PSLGSP

Specific function: Unknown

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR002912
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF01842 ACT; PF02153 PDH [H]

EC number: =1.3.1.12 [H]

Molecular weight: Translated: 33659; Mature: 33528

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILDGGWDCVGRPVCVLGLGLIGGSIMRATAEAGREVFGYNRSVKGAQSARSDGFDATT
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHH
KLADALVRAADTHALIVLAVPMPALPAMLAHIRELAPNCPLTDVTSVKTAVLDAVVSVGL
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
QARFVGGHPMTGTAQSGWGAGHGGLFNRTSWVLSVDDHVDPAVWSMVMTLALDCGALVLP
CEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEC
AKSDEHDAAAAAISHMPHLLAEALAVAAAEVPLAFAVAAGSFRDATRVAGTAPDLVRAMC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHCCCCHHHHHHHH
EGNSGQLLSSVDRVIELLCRARDSLACNNSVAELVEAGHAARARYDSFPRSDIVTVIIGA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHCCCCCCCEEEEEECC
ENWREDLAAAGRAGGVIRSALPSLGSP
CHHHHHHHHCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SILDGGWDCVGRPVCVLGLGLIGGSIMRATAEAGREVFGYNRSVKGAQSARSDGFDATT
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHH
KLADALVRAADTHALIVLAVPMPALPAMLAHIRELAPNCPLTDVTSVKTAVLDAVVSVGL
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
QARFVGGHPMTGTAQSGWGAGHGGLFNRTSWVLSVDDHVDPAVWSMVMTLALDCGALVLP
CEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEC
AKSDEHDAAAAAISHMPHLLAEALAVAAAEVPLAFAVAAGSFRDATRVAGTAPDLVRAMC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHCCCCHHHHHHHH
EGNSGQLLSSVDRVIELLCRARDSLACNNSVAELVEAGHAARARYDSFPRSDIVTVIIGA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHCCCCCCCEEEEEECC
ENWREDLAAAGRAGGVIRSALPSLGSP
CHHHHHHHHCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3106153; 9384377 [H]