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The map label for this gene is deoC

Identifier: 221230803

GI number: 221230803

Start: 2926454

End: 2927134

Strand: Reverse

Name: deoC

Synonym: MLBr_02451

Alternate gene names: 221230803

Gene position: 2927134-2926454 (Counterclockwise)

Preceding gene: 221230804

Following gene: 221230800

Centisome position: 89.57

GC content: 64.02

Gene sequence:

>681_bases
GTGCAGGGCCAACCTACTCGGAAACAGTTGGCGGCGCTGGTTGACCATACCCTGCTCAAGTCCGAGGCGACCCATGCTGA
TGTGGCTGCTCTTGTTGCCGAAGCTGTTGAGCTGGGCGTCTACGCGGTGTGTGTCTCCCCGTCGATGGTGCCGGCCGCCG
TCGAAGCCGGTGCGGGTGGTTTGCGGGTTGCTACGGTGGTCGGGTTTCCGTCGGGCGAGCATGTGTCCATTGTCAAGGCG
CAAGAGGCAGTTCAGGCCGTAGCATCCGGTGCAACTGAGATCGACATGGTCATCGCCGTCGGTGCTGCGTTGGCTGGAGA
CCTCGATGCGGTGCGGTCCGATATCGAGATGGTGCGCTCCGCTATAGCCGGTGTCGTACTCAAGGTGATTGTGGAGTCGG
CGGTGCTGTTGGGCCAGGCAAACGAACGTACGCTGGCTGAAGTGTGTCACGTCGCGGAAGCCGCCGGCGCGGACTTCGTC
AAGACCTCGACTGGGTTTCATCCCGCTGGGGGAGCGTCGGTGCGTGCTGTCACGCTGATGACCGAGGCCGTCGGGGGCCG
GCTAGGGGTCAAGGCCAGCGGCGGCATCCGTACCGCCGTTGACGCGATCGCACTGCTGGACGCTGGTGCCACGAGGCTGG
GCCTGTCTTCCACTCGAGAAGTGCTGGATGGGCTCAGCTAA

Upstream 100 bases:

>100_bases
AGCCATGGCGTCCCGTCGTCGATGACTCCGAGATATTCGCTGCCGGTTGCCATCCCGGTATATCCGAAGGAATACAGCAA
GCCGACGAGGGACCGCGGTA

Downstream 100 bases:

>100_bases
ACTCTATTTGTTTTCCTGTGCAGGTCGAGCGATGGCTGCCGGGCGTCACGAAGCCCTTAGAGGTTAGCGAAACAGGGGTC
CTGACCGCCTGTGCTGTTGG

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MQGQPTRKQLAALVDHTLLKSEATHADVAALVAEAVELGVYAVCVSPSMVPAAVEAGAGGLRVATVVGFPSGEHVSIVKA
QEAVQAVASGATEIDMVIAVGAALAGDLDAVRSDIEMVRSAIAGVVLKVIVESAVLLGQANERTLAEVCHVAEAAGADFV
KTSTGFHPAGGASVRAVTLMTEAVGGRLGVKASGGIRTAVDAIALLDAGATRLGLSSTREVLDGLS

Sequences:

>Translated_226_residues
MQGQPTRKQLAALVDHTLLKSEATHADVAALVAEAVELGVYAVCVSPSMVPAAVEAGAGGLRVATVVGFPSGEHVSIVKA
QEAVQAVASGATEIDMVIAVGAALAGDLDAVRSDIEMVRSAIAGVVLKVIVESAVLLGQANERTLAEVCHVAEAAGADFV
KTSTGFHPAGGASVRAVTLMTEAVGGRLGVKASGGIRTAVDAIALLDAGATRLGLSSTREVLDGLS
>Mature_226_residues
MQGQPTRKQLAALVDHTLLKSEATHADVAALVAEAVELGVYAVCVSPSMVPAAVEAGAGGLRVATVVGFPSGEHVSIVKA
QEAVQAVASGATEIDMVIAVGAALAGDLDAVRSDIEMVRSAIAGVVLKVIVESAVLLGQANERTLAEVCHVAEAAGADFV
KTSTGFHPAGGASVRAVTLMTEAVGGRLGVKASGGIRTAVDAIALLDAGATRLGLSSTREVLDGLS

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=183, Percent_Identity=36.0655737704918, Blast_Score=85, Evalue=7e-17,
Organism=Escherichia coli, GI1790841, Length=208, Percent_Identity=35.0961538461538, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17533015, Length=227, Percent_Identity=28.1938325991189, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19922098, Length=196, Percent_Identity=33.6734693877551, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_MYCLB (B8ZT93)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002504219.1
- ProteinModelPortal:   B8ZT93
- SMR:   B8ZT93
- EnsemblBacteria:   EBMYCT00000087183
- GeneID:   7324764
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000017372
- HOGENOM:   HBG636421
- OMA:   WRAIETE
- ProtClustDB:   PRK00507
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 22527; Mature: 22527

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: ACT_SITE 161-161 ACT_SITE 191-191

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGQPTRKQLAALVDHTLLKSEATHADVAALVAEAVELGVYAVCVSPSMVPAAVEAGAGG
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHCCCCC
LRVATVVGFPSGEHVSIVKAQEAVQAVASGATEIDMVIAVGAALAGDLDAVRSDIEMVRS
EEEEEEEECCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AIAGVVLKVIVESAVLLGQANERTLAEVCHVAEAAGADFVKTSTGFHPAGGASVRAVTLM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHH
TEAVGGRLGVKASGGIRTAVDAIALLDAGATRLGLSSTREVLDGLS
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCHHHHHHHHCCCC
>Mature Secondary Structure
MQGQPTRKQLAALVDHTLLKSEATHADVAALVAEAVELGVYAVCVSPSMVPAAVEAGAGG
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHCCCCC
LRVATVVGFPSGEHVSIVKAQEAVQAVASGATEIDMVIAVGAALAGDLDAVRSDIEMVRS
EEEEEEEECCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AIAGVVLKVIVESAVLLGQANERTLAEVCHVAEAAGADFVKTSTGFHPAGGASVRAVTLM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHH
TEAVGGRLGVKASGGIRTAVDAIALLDAGATRLGLSSTREVLDGLS
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA