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The map label for this gene is infC [H]

Identifier: 221230206

GI number: 221230206

Start: 1675740

End: 1676297

Strand: Direct

Name: infC [H]

Synonym: MLBr_01394

Alternate gene names: 221230206

Gene position: 1675740-1676297 (Clockwise)

Preceding gene: 221230204

Following gene: 221230207

Centisome position: 51.28

GC content: 58.42

Gene sequence:

>558_bases
TTGATTGGTCCAGGGGGGGAGCAGGTAGGCATCGTACGGATCGAGGATGCACTTCGCGTGGCTGCGGACGCCGATCTCGA
CCTTGTCGAAGTTGCCCCAAATGCCAGACCACCGGTTTGCAAGATCATGGACTACGGCAAGTACAAATACGAAGTGGCAC
AGAAGGCACGCGAATCCCGCCGCAACCAGCAGCAGACCGTCGTCAAAGAACAAAAGTTGCGACCAAAGATCGACGATCAT
GATTACGAGACCAAAAAGAGCCACGTGGTCCGTTTCCTGGAGGCGGGATCCAAGGTCAAAGTCACCATCATGTTTCGCGG
ACGTGAGCAGTCGCGACCCGAGCTGGGTTACCGATTACTGCAGCGACTGGGTGCGGACGTCGCCGATTACGGATTCGTCG
AAACATCAGCCAAACAGGATGGGCGCAACATGACGATGGTGCTGGCACCGCATCGCGGCGCGAAGACTCGCGCCAGCGCG
CGGCATCCGGAAGTACCGGGGGCTGGGTCAGTGCAAGATATCGATGCAACCGGCGACACCGATGGTTCACCGCACTAG

Upstream 100 bases:

>100_bases
GCTAAGTAGATGACTATTACGCCCACTATGGCCCAACAAGGGAGGCCCCATCAGCACTGAGACCCGTGTCAACGAGCGCA
TACGCGTACCTGAAGTCCGG

Downstream 100 bases:

>100_bases
CGAGTTAGCCAGCGCAGGAAGAACAGTAGAAACAGCAGAACTGAGGAAACATGCCCAAGGCCAAGACCCACAGTGGGGCG
TCGAAGCGGTTCCGGCGCAC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEVAQKARESRRNQQQTVVKEQKLRPKIDDH
DYETKKSHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFVETSAKQDGRNMTMVLAPHRGAKTRASA
RHPEVPGAGSVQDIDATGDTDGSPH

Sequences:

>Translated_185_residues
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEVAQKARESRRNQQQTVVKEQKLRPKIDDH
DYETKKSHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFVETSAKQDGRNMTMVLAPHRGAKTRASA
RHPEVPGAGSVQDIDATGDTDGSPH
>Mature_185_residues
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEVAQKARESRRNQQQTVVKEQKLRPKIDDH
DYETKKSHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFVETSAKQDGRNMTMVLAPHRGAKTRASA
RHPEVPGAGSVQDIDATGDTDGSPH

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=153, Percent_Identity=45.7516339869281, Blast_Score=133, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20481; Mature: 20481

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEVAQKARESR
CCCCCCCEEEEEEEHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHH
RNQQQTVVKEQKLRPKIDDHDYETKKSHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHH
QRLGADVADYGFVETSAKQDGRNMTMVLAPHRGAKTRASARHPEVPGAGSVQDIDATGDT
HHHCCCHHHCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCC
DGSPH
CCCCC
>Mature Secondary Structure
MIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEVAQKARESR
CCCCCCCEEEEEEEHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHH
RNQQQTVVKEQKLRPKIDDHDYETKKSHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHH
QRLGADVADYGFVETSAKQDGRNMTMVLAPHRGAKTRASARHPEVPGAGSVQDIDATGDT
HHHCCCHHHCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCC
DGSPH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]