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The map label for this gene is 221230179

Identifier: 221230179

GI number: 221230179

Start: 1611453

End: 1612097

Strand: Direct

Name: 221230179

Synonym: MLBr_01351

Alternate gene names: NA

Gene position: 1611453-1612097 (Clockwise)

Preceding gene: 221230178

Following gene: 221230180

Centisome position: 49.31

GC content: 62.17

Gene sequence:

>645_bases
TTGCGATCACCACGGCGGTGCAAAATCTGTGCCGTGAGTGCTGACCAATTGGTTGTTGACCCGGTTGTTGCCGCGCATCG
ACTACTCGGTGCCACCATCACCGGCCGGGGAGTGTGTGCCATCGTCGTTGAGGTGGAGGCGTACGGTGGGGTTCCCGACG
GTCCCTGGCCCGACGCCGCCGCCCACTCCTACCACGGCCGGAACGACCGTAACGCTGTGATGTTTGGGCCGCCCGGCCGA
CTCTACACTTACTGTAGCCACGGCATCCATGTATGCGCCAATGTCTCGTGTGGACCGGATGGGACGGCTGCCGCAGTCCT
TATTCGGGCCGGTGCTCTCGAGAACGGCGCCGACGTCGCCCGGTCTCGGCGCGGCGCGTCAGTCCGTACTGTTGCGTTAG
CGCGTGGACCCGGAAATCTGTGCTCTGCTTTAGGAATTACTATGGATGACAACGGTATTGATGTATTTGCTGCTGACAGC
CCGGTGACATTGGTCCTCAATGAGGCTCAGGAAGCGATGTCGGGTCCACGTGTTGGAATCAGTCACGCAGCCGACCGACC
CTGGCGATTGTGGCTGCCGGGCCGACCCGAAGTCTCGACTTATCGTCGAAGTCCCCGAGCTCCGGCTCCCGGTGCTAGCG
ACTAG

Upstream 100 bases:

>100_bases
TGAGGTTAATTCATCGTGCGATGAATTCTGTCTCCTAACACGGAGTTGTCAAGAGCCACGGCGTGGTGGTGGTAATCCGC
TGCGCGCAACTCCGCTGCGC

Downstream 100 bases:

>100_bases
CCTCTTTTGGGTGTCTTCCAGCATCCTTAACGAGCTGGGCTGGCGTGGGTTGGTCGCGCAGTCCACTGACCTCGATGCTC
TAGCCGACGAGTTGCGGCGT

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MRSPRRCKICAVSADQLVVDPVVAAHRLLGATITGRGVCAIVVEVEAYGGVPDGPWPDAAAHSYHGRNDRNAVMFGPPGR
LYTYCSHGIHVCANVSCGPDGTAAAVLIRAGALENGADVARSRRGASVRTVALARGPGNLCSALGITMDDNGIDVFAADS
PVTLVLNEAQEAMSGPRVGISHAADRPWRLWLPGRPEVSTYRRSPRAPAPGASD

Sequences:

>Translated_214_residues
MRSPRRCKICAVSADQLVVDPVVAAHRLLGATITGRGVCAIVVEVEAYGGVPDGPWPDAAAHSYHGRNDRNAVMFGPPGR
LYTYCSHGIHVCANVSCGPDGTAAAVLIRAGALENGADVARSRRGASVRTVALARGPGNLCSALGITMDDNGIDVFAADS
PVTLVLNEAQEAMSGPRVGISHAADRPWRLWLPGRPEVSTYRRSPRAPAPGASD
>Mature_214_residues
MRSPRRCKICAVSADQLVVDPVVAAHRLLGATITGRGVCAIVVEVEAYGGVPDGPWPDAAAHSYHGRNDRNAVMFGPPGR
LYTYCSHGIHVCANVSCGPDGTAAAVLIRAGALENGADVARSRRGASVRTVALARGPGNLCSALGITMDDNGIDVFAADS
PVTLVLNEAQEAMSGPRVGISHAADRPWRLWLPGRPEVSTYRRSPRAPAPGASD

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=144, Percent_Identity=38.1944444444444, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI62632771, Length=144, Percent_Identity=38.1944444444444, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI62632765, Length=144, Percent_Identity=38.1944444444444, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_MYCLB (B8ZRG8)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503595.1
- ProteinModelPortal:   B8ZRG8
- SMR:   B8ZRG8
- EnsemblBacteria:   EBMYCT00000085399
- GeneID:   7326494
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000017493
- HOGENOM:   HBG664239
- OMA:   LCSGPGK
- ProtClustDB:   PRK00802
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 22314; Mature: 22314

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPRRCKICAVSADQLVVDPVVAAHRLLGATITGRGVCAIVVEVEAYGGVPDGPWPDAA
CCCCCCEEEEEECCCCEEHHHHHHHHHHHCCEECCCCEEEEEEEEEECCCCCCCCCCCCC
AHSYHGRNDRNAVMFGPPGRLYTYCSHGIHVCANVSCGPDGTAAAVLIRAGALENGADVA
CCCCCCCCCCCEEEECCCCCEEEEECCCEEEEEECCCCCCCHHEEEEEECCCCCCCHHHH
RSRRGASVRTVALARGPGNLCSALGITMDDNGIDVFAADSPVTLVLNEAQEAMSGPRVGI
HHCCCCCEEEEEEECCCCHHHHHCCCEECCCCEEEEECCCCEEEEEECHHHHHCCCCCCC
SHAADRPWRLWLPGRPEVSTYRRSPRAPAPGASD
CCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRSPRRCKICAVSADQLVVDPVVAAHRLLGATITGRGVCAIVVEVEAYGGVPDGPWPDAA
CCCCCCEEEEEECCCCEEHHHHHHHHHHHCCEECCCCEEEEEEEEEECCCCCCCCCCCCC
AHSYHGRNDRNAVMFGPPGRLYTYCSHGIHVCANVSCGPDGTAAAVLIRAGALENGADVA
CCCCCCCCCCCEEEECCCCCEEEEECCCEEEEEECCCCCCCHHEEEEEECCCCCCCHHHH
RSRRGASVRTVALARGPGNLCSALGITMDDNGIDVFAADSPVTLVLNEAQEAMSGPRVGI
HHCCCCCEEEEEEECCCCHHHHHCCCEECCCCEEEEECCCCEEEEEECHHHHHCCCCCCC
SHAADRPWRLWLPGRPEVSTYRRSPRAPAPGASD
CCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA