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The map label for this gene is hisE

Identifier: 221230155

GI number: 221230155

Start: 1561989

End: 1562270

Strand: Direct

Name: hisE

Synonym: MLBr_01309

Alternate gene names: 221230155

Gene position: 1561989-1562270 (Clockwise)

Preceding gene: 221230154

Following gene: 221230156

Centisome position: 47.8

GC content: 59.57

Gene sequence:

>282_bases
GTGAAACAATCGCTGGCCGTGAAGACCTTCGAGGATCTGTTCGCCGAACTCAGCGAACGTGCCCGTACCCGGCCTACCGA
CAGTGCCACAGTGGCCTCCCTGGACGGTGGGATACATGCGCTGGGCAAAAAGATCCTAGAGGAGGCCGGCGAGGTGTGGT
TGGCTGCCGAACACGAACCCAAGGAAGTGTTGGCCGAAGAGATCAGCCAGTTGCTGTACTGGACCCAGGTGCTGATGATC
TCGCGCGGACTGTCGCTCGATGACGTCTATCGGAAGCTGTGA

Upstream 100 bases:

>100_bases
TGGCCATGCTCAACGGCACGTTGTTTGCGGTTTTGCCGCTGCGCGACTGGGGGCGTATCAAGTCGACCGGTGAAACCGCC
GCGACTTTGCTGGCTGGCAT

Downstream 100 bases:

>100_bases
GCATGCTGCGGGTTGCCGTTCCTAACAAAGGTGCGCTAAGCGAGCCGGCTACCGAGATCCTTGCTGAGGCTGGCTATCGA
CGACGCACTGATCCCAAAGA

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH

Number of amino acids: Translated: 93; Mature: 93

Protein sequence:

>93_residues
MKQSLAVKTFEDLFAELSERARTRPTDSATVASLDGGIHALGKKILEEAGEVWLAAEHEPKEVLAEEISQLLYWTQVLMI
SRGLSLDDVYRKL

Sequences:

>Translated_93_residues
MKQSLAVKTFEDLFAELSERARTRPTDSATVASLDGGIHALGKKILEEAGEVWLAAEHEPKEVLAEEISQLLYWTQVLMI
SRGLSLDDVYRKL
>Mature_93_residues
MKQSLAVKTFEDLFAELSERARTRPTDSATVASLDGGIHALGKKILEEAGEVWLAAEHEPKEVLAEEISQLLYWTQVLMI
SRGLSLDDVYRKL

Specific function: Unknown

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS2_MYCLB (B8ZRE4)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503571.1
- ProteinModelPortal:   B8ZRE4
- SMR:   B8ZRE4
- EnsemblBacteria:   EBMYCT00000085894
- GeneID:   7324991
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000017721
- HOGENOM:   HBG646527
- OMA:   VWMAAEY
- ProtClustDB:   PRK00400
- GO:   GO:0005737
- HAMAP:   MF_01020
- InterPro:   IPR008179
- InterPro:   IPR021130
- TIGRFAMs:   TIGR03188

Pfam domain/function: PF01503 PRA-PH

EC number: =3.6.1.31

Molecular weight: Translated: 10415; Mature: 10415

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSLAVKTFEDLFAELSERARTRPTDSATVASLDGGIHALGKKILEEAGEVWLAAEHEP
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCH
KEVLAEEISQLLYWTQVLMISRGLSLDDVYRKL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MKQSLAVKTFEDLFAELSERARTRPTDSATVASLDGGIHALGKKILEEAGEVWLAAEHEP
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCH
KEVLAEEISQLLYWTQVLMISRGLSLDDVYRKL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA