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The map label for this gene is yggV [C]

Identifier: 221230071

GI number: 221230071

Start: 1371822

End: 1372484

Strand: Direct

Name: yggV [C]

Synonym: MLBr_01175

Alternate gene names: 221230071

Gene position: 1371822-1372484 (Clockwise)

Preceding gene: 221230070

Following gene: 221230081

Centisome position: 41.98

GC content: 63.35

Gene sequence:

>663_bases
GTGGGGGTATCTCCCAGCCGTGAAGCGGCGAGAGGGGTGGCGCTTGTGACCAAGCTATTGGTCGCTAGCCGTAACTGGAA
GAAGCTGGCAGAATTGCGCCGTGTGCTCGACAATGCCGGGTTGTCGGGGTTGACGCTGGTATCGCTGAACGACGTGGTGC
CGTTCGATGAGGCCCCGGAAGCCGGCGCCACTTTCGAGGACAACGCGTTGGCCAAGGCACGCGATGCGTTTGCAGCCACG
GGTTTGGCGAGTGTGGCCGACGACTCGGGTTTGGAGGCGGCTGCGCTGGGTGGCATGCCAGGGGTGCTGTCAGCGCGTTG
GTCGGGTAGTTACGGCGACGACGCCGGCAACACCGCGCTATTGCTGGCTCAATTGTGTGATGTGCCTGACGAGCGGCGCA
GCGCGGCATTCGTGTCGGCCTGTGCGCTGGTCTCGGAGTCCGACGAAGTCGTCGTCCGAGGGGTGTGGCCGGGCACGATT
GCCAGGGAGCCGCGCGGTTACGGTGGGTTTGGCTATGATTCGATCTTCATTCCTGACGGTCCTGGCCTGGGAGGCCGCAC
AGTGGCTCAATTAAGGCCGGCGGAAAAGGATGCGTTCTCGCATCGCTTCCGTGCGTTAACGTTGCTGATGCCTGCGCTGC
GTGTTCTTGCCATGCGAACGTGA

Upstream 100 bases:

>100_bases
TTGGCGCTGCCGTATCAGGGTATGTCCCCTGAGGGACCGCCACCGCCGAAGGCGTTCGGCAGCTGAGTGTGCCGGCGACG
ATGCAGAGCGGAGTGATGAT

Downstream 100 bases:

>100_bases
AGCTGGCCGCGATGCGAGAACGAGTGTGCGGCCAGGCGCTTCACGTTCGACTGTGTCTAAGCCCGAAGCGCGTCTTGACG
TCTTTGGTTTGGAAGTGCTC

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MGVSPSREAARGVALVTKLLVASRNWKKLAELRRVLDNAGLSGLTLVSLNDVVPFDEAPEAGATFEDNALAKARDAFAAT
GLASVADDSGLEAAALGGMPGVLSARWSGSYGDDAGNTALLLAQLCDVPDERRSAAFVSACALVSESDEVVVRGVWPGTI
AREPRGYGGFGYDSIFIPDGPGLGGRTVAQLRPAEKDAFSHRFRALTLLMPALRVLAMRT

Sequences:

>Translated_220_residues
MGVSPSREAARGVALVTKLLVASRNWKKLAELRRVLDNAGLSGLTLVSLNDVVPFDEAPEAGATFEDNALAKARDAFAAT
GLASVADDSGLEAAALGGMPGVLSARWSGSYGDDAGNTALLLAQLCDVPDERRSAAFVSACALVSESDEVVVRGVWPGTI
AREPRGYGGFGYDSIFIPDGPGLGGRTVAQLRPAEKDAFSHRFRALTLLMPALRVLAMRT
>Mature_219_residues
GVSPSREAARGVALVTKLLVASRNWKKLAELRRVLDNAGLSGLTLVSLNDVVPFDEAPEAGATFEDNALAKARDAFAATG
LASVADDSGLEAAALGGMPGVLSARWSGSYGDDAGNTALLLAQLCDVPDERRSAAFVSACALVSESDEVVVRGVWPGTIA
REPRGYGGFGYDSIFIPDGPGLGGRTVAQLRPAEKDAFSHRFRALTLLMPALRVLAMRT

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=205, Percent_Identity=44.390243902439, Blast_Score=143, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22987; Mature: 22856

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVSPSREAARGVALVTKLLVASRNWKKLAELRRVLDNAGLSGLTLVSLNDVVPFDEAPE
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
AGATFEDNALAKARDAFAATGLASVADDSGLEAAALGGMPGVLSARWSGSYGDDAGNTAL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEECCCCCCCCCCCCHHH
LLAQLCDVPDERRSAAFVSACALVSESDEVVVRGVWPGTIAREPRGYGGFGYDSIFIPDG
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCC
PGLGGRTVAQLRPAEKDAFSHRFRALTLLMPALRVLAMRT
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GVSPSREAARGVALVTKLLVASRNWKKLAELRRVLDNAGLSGLTLVSLNDVVPFDEAPE
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
AGATFEDNALAKARDAFAATGLASVADDSGLEAAALGGMPGVLSARWSGSYGDDAGNTAL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEECCCCCCCCCCCCHHH
LLAQLCDVPDERRSAAFVSACALVSESDEVVVRGVWPGTIAREPRGYGGFGYDSIFIPDG
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCC
PGLGGRTVAQLRPAEKDAFSHRFRALTLLMPALRVLAMRT
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]