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The map label for this gene is argS

Identifier: 221230035

GI number: 221230035

Start: 1316611

End: 1318263

Strand: Direct

Name: argS

Synonym: MLBr_01127

Alternate gene names: 221230035

Gene position: 1316611-1318263 (Clockwise)

Preceding gene: 221230030

Following gene: 221230036

Centisome position: 40.29

GC content: 60.19

Gene sequence:

>1653_bases
GTGACCCCTGCCGATCTGGCTGAGCTGCTCAAAACAACCGCTATTGTGGTGCTGGCTGAGCGCGGGCTCGATGCCGCTGC
GTTGCCGCAGACGGTCACCGTGGAGCGGCCGCGAAATCCTGAGCACGGAGATTACTCCAGCAACCTGGCCATGCAGCTGG
GCAAAAAAGTCGGTGCAAACCCGCTTGAACTAGCCGGATGGCTTGCCGAGGTGCTGGCGCAGGCCGGCGGCATCGCGGAC
GTAGAGGTGGCGGGACCGGGTTTCATCAACATGCGTCTTGACGCGTCGGCGCAGGCCATGATTGTCAACACCGTCATCAA
CGCCGATAAAAACTTCGGCCACTCCGATGACCTGGCTGGTTACCAGATCAACCTAGAATTCGTCTCGGCCAACCCGACCG
GACCGATCCACATCGGCGGCACTCGGTGGGCAGCTGTCGGGGACGCACTGGGTCGGTTGTTGTCGACGCAGGGTGCCGCT
GTGGTGCGCGAATACTATTTCAACGACCACGGCGCCCAGATCGACCGGTTCACCAACTCTTTGATCGCCGCGGCCAAAGG
CGAGCTCACTCCGGCCGACGGCTACGCTGGCACCTACGTAACCGACATCGCCGCGCAGGTGATGCAGCAGGCACCCTACG
CGCTGAGCCTGCCCGAATCCGAGATGCACGAGACCGTCCGCGAAATCGGCGTCGACTTGATGTTCACCCACATCAAAAAG
TCGTTGCACGAGTTCGGCACCGATTTCGATGTCTACACCCACGAAGACTCGATGCATGCCAGCGGCCGGGTCGATGAGGC
CATCGCCAGACTGCGCGATACCGGTAATGTTTACGAAAAGGATGGTGCACTCTGGTTGCGCACCAGCGCTTTTGGTGACG
ACAAGGACCGTGTCGTGATCAAGAGCGACGGCAAGCCGGCCTATATCGCCGGTGATCTTGCCTACTACCTGGACAAGCGG
CAACGCGGTTTCGACTTGTGCATCTACATGCTTGGTGCCGACCACCACGGATATATCGCCCGGCTCAAGGCTGCGGCCGC
CGCATTCGGCGATGACCCGGCCATCGTCGAGGTGCTCATCGGACAGATGGTGAACCTGGTTTGCGATGGACAGCTGGTCC
GGATGAGTAAGCGCTCAGGCAACGTGATTACGCTCGACGACCTGGTCGAGGCGATTGGTGTCGACGCCGCGCGCTACAGC
CTGATCCGCTCGTCGGTGGACACTCCGATTGACATTGACTTGGCACTGTGGTCCTCGTCCTCGAATGAAAACCCTGTTTA
TTATGTGCAATACGCGCATGCCCGCCTATCGGCATTGGCTCGTAACGCTGCCGAATTCGGACTGATTCCCGACACCGGAC
ACCTCGAGCTGCTCAGTCACGACAAGGAAGGTGCACTATTACGTACCGTCGGTGAATTCCCCCAGGTGCTCAAAACCGCT
GCTGCACTGCGTGAACCACACCGTGTATGCCGTTATTTGGAAGACCTCGCCGGAGATTACCACCGGTTCTATGACTCCTG
CCGGGTATTGCCCCAAGGCGACGAGAAGCCTACCGACCTGCACACCGCGCGTTTGGCCCTGTGCCAGGCCAATCGTCAGG
TTATTGCCAACGGGCTGGCGATCCTCGGAGTCAGTGCTCCGGAGCGGATGTGA

Upstream 100 bases:

>100_bases
GTCCCCACTTCTGACGGCTACGCCGTCTGAACTATTGCGAGGCTGGCTGCTACTGCGACGGATTCGGGCGTTATGGCCAC
AGCCCATAGGATGGACATTC

Downstream 100 bases:

>100_bases
ACGTACATACCGCCGGTCCTCGGCACGCTGAAAAAACCCGTCACACCGCGACTCCACAGCGTGTGCAACCCTCAGATGAC
CTGTTGCGATTAGCGTCAAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTPADLAELLKTTAIVVLAERGLDAAALPQTVTVERPRNPEHGDYSSNLAMQLGKKVGANPLELAGWLAEVLAQAGGIAD
VEVAGPGFINMRLDASAQAMIVNTVINADKNFGHSDDLAGYQINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAA
VVREYYFNDHGAQIDRFTNSLIAAAKGELTPADGYAGTYVTDIAAQVMQQAPYALSLPESEMHETVREIGVDLMFTHIKK
SLHEFGTDFDVYTHEDSMHASGRVDEAIARLRDTGNVYEKDGALWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKR
QRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPAIVEVLIGQMVNLVCDGQLVRMSKRSGNVITLDDLVEAIGVDAARYS
LIRSSVDTPIDIDLALWSSSSNENPVYYVQYAHARLSALARNAAEFGLIPDTGHLELLSHDKEGALLRTVGEFPQVLKTA
AALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEKPTDLHTARLALCQANRQVIANGLAILGVSAPERM

Sequences:

>Translated_550_residues
MTPADLAELLKTTAIVVLAERGLDAAALPQTVTVERPRNPEHGDYSSNLAMQLGKKVGANPLELAGWLAEVLAQAGGIAD
VEVAGPGFINMRLDASAQAMIVNTVINADKNFGHSDDLAGYQINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAA
VVREYYFNDHGAQIDRFTNSLIAAAKGELTPADGYAGTYVTDIAAQVMQQAPYALSLPESEMHETVREIGVDLMFTHIKK
SLHEFGTDFDVYTHEDSMHASGRVDEAIARLRDTGNVYEKDGALWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKR
QRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPAIVEVLIGQMVNLVCDGQLVRMSKRSGNVITLDDLVEAIGVDAARYS
LIRSSVDTPIDIDLALWSSSSNENPVYYVQYAHARLSALARNAAEFGLIPDTGHLELLSHDKEGALLRTVGEFPQVLKTA
AALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEKPTDLHTARLALCQANRQVIANGLAILGVSAPERM
>Mature_549_residues
TPADLAELLKTTAIVVLAERGLDAAALPQTVTVERPRNPEHGDYSSNLAMQLGKKVGANPLELAGWLAEVLAQAGGIADV
EVAGPGFINMRLDASAQAMIVNTVINADKNFGHSDDLAGYQINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAAV
VREYYFNDHGAQIDRFTNSLIAAAKGELTPADGYAGTYVTDIAAQVMQQAPYALSLPESEMHETVREIGVDLMFTHIKKS
LHEFGTDFDVYTHEDSMHASGRVDEAIARLRDTGNVYEKDGALWLRTSAFGDDKDRVVIKSDGKPAYIAGDLAYYLDKRQ
RGFDLCIYMLGADHHGYIARLKAAAAAFGDDPAIVEVLIGQMVNLVCDGQLVRMSKRSGNVITLDDLVEAIGVDAARYSL
IRSSVDTPIDIDLALWSSSSNENPVYYVQYAHARLSALARNAAEFGLIPDTGHLELLSHDKEGALLRTVGEFPQVLKTAA
ALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEKPTDLHTARLALCQANRQVIANGLAILGVSAPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1788184, Length=565, Percent_Identity=24.7787610619469, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320548, Length=557, Percent_Identity=26.032315978456, Blast_Score=123, Evalue=8e-29,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_MYCLB (B8ZR24)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503451.1
- ProteinModelPortal:   B8ZR24
- EnsemblBacteria:   EBMYCT00000085862
- GeneID:   7327228
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016532
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 59604; Mature: 59473

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPADLAELLKTTAIVVLAERGLDAAALPQTVTVERPRNPEHGDYSSNLAMQLGKKVGAN
CCHHHHHHHHHHHHEEEEECCCCCHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCC
PLELAGWLAEVLAQAGGIADVEVAGPGFINMRLDASAQAMIVNTVINADKNFGHSDDLAG
HHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCC
YQINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAAVVREYYFNDHGAQIDRFTNS
EEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
LIAAAKGELTPADGYAGTYVTDIAAQVMQQAPYALSLPESEMHETVREIGVDLMFTHIKK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCHHHHHHHHHH
SLHEFGTDFDVYTHEDSMHASGRVDEAIARLRDTGNVYEKDGALWLRTSAFGDDKDRVVI
HHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCEEEE
KSDGKPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPAIVEVLI
ECCCCCEEEEHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHH
GQMVNLVCDGQLVRMSKRSGNVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSS
HHHHHHHCCCHHEEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCC
SNENPVYYVQYAHARLSALARNAAEFGLIPDTGHLELLSHDKEGALLRTVGEFPQVLKTA
CCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
AALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEKPTDLHTARLALCQANRQVIANGLA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHCCEE
ILGVSAPERM
EEECCCCCCC
>Mature Secondary Structure 
TPADLAELLKTTAIVVLAERGLDAAALPQTVTVERPRNPEHGDYSSNLAMQLGKKVGAN
CHHHHHHHHHHHHEEEEECCCCCHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCC
PLELAGWLAEVLAQAGGIADVEVAGPGFINMRLDASAQAMIVNTVINADKNFGHSDDLAG
HHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCC
YQINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAAVVREYYFNDHGAQIDRFTNS
EEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
LIAAAKGELTPADGYAGTYVTDIAAQVMQQAPYALSLPESEMHETVREIGVDLMFTHIKK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCHHHHHHHHHH
SLHEFGTDFDVYTHEDSMHASGRVDEAIARLRDTGNVYEKDGALWLRTSAFGDDKDRVVI
HHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCEEEE
KSDGKPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAAFGDDPAIVEVLI
ECCCCCEEEEHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHH
GQMVNLVCDGQLVRMSKRSGNVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSS
HHHHHHHCCCHHEEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCC
SNENPVYYVQYAHARLSALARNAAEFGLIPDTGHLELLSHDKEGALLRTVGEFPQVLKTA
CCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
AALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEKPTDLHTARLALCQANRQVIANGLA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHCCEE
ILGVSAPERM
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA