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The map label for this gene is nrdR [H]

Identifier: 221229958

GI number: 221229958

Start: 1176704

End: 1177168

Strand: Direct

Name: nrdR [H]

Synonym: MLBr_01005

Alternate gene names: 221229958

Gene position: 1176704-1177168 (Clockwise)

Preceding gene: 221229957

Following gene: 221229959

Centisome position: 36.01

GC content: 61.08

Gene sequence:

>465_bases
ATGCATTGCCCGTTCTGCAGGCATTCCGATTCCAGGGTGATTGATTCGCGAGAAACTGATGAAGGCCAAGCGATTCGACG
CCGTCGGTCGTGCCCAGAGTGCGGGCGGCGGTTCACCACCGTAGAAACTGCTGTGGTGGCCGTCGTGAAGCGCAGCGGTG
TTACGGAGCCCTTCAGCCGGGGGAAGGTCATTCGCGGCGTCCGTCGGGCTTGTCAGGGTCGCCAAGTAGATGACGACGCG
CTGAACCTCTTGGCCCAGCAGGTGGAAGACACCGTTCGTGCTGCGGGGTTGCCAGAGGTCCCAAGTCACGAGGTTGGCCT
GGCGATCCTTGGGCCGTTACGCGAACTCGACGAAGTGGCTTATTTGCGTTTCGCGTCGGTATACCGATCCTTTTCGTCGG
CCGACGACTTCGAGCGCGAGATTGAGGCGCTTCGCGCACACCGCAGAGTATCCACTTCACGCTGA

Upstream 100 bases:

>100_bases
GAACGCGCATGTGTGGCGGCAGTATTCGTTGGTTGGGGCAGTGACAGGTATTCTCGGAACGTCTGCGATACCTTGACATC
AGCCCGGCAAAGGAGCGGTC

Downstream 100 bases:

>100_bases
CGGATTGCAGTGGATGGCTCGGTTCCCATTAGGCTGACTGCATGCCTTCCGATCTGTGCCCTGATCTTCAGGCACTGGCA
CCGCTGCTTGGTTCGTGGGT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MHCPFCRHSDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVVAVVKRSGVTEPFSRGKVIRGVRRACQGRQVDDDA
LNLLAQQVEDTVRAAGLPEVPSHEVGLAILGPLRELDEVAYLRFASVYRSFSSADDFEREIEALRAHRRVSTSR

Sequences:

>Translated_154_residues
MHCPFCRHSDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVVAVVKRSGVTEPFSRGKVIRGVRRACQGRQVDDDA
LNLLAQQVEDTVRAAGLPEVPSHEVGLAILGPLRELDEVAYLRFASVYRSFSSADDFEREIEALRAHRRVSTSR
>Mature_154_residues
MHCPFCRHSDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVVAVVKRSGVTEPFSRGKVIRGVRRACQGRQVDDDA
LNLLAQQVEDTVRAAGLPEVPSHEVGLAILGPLRELDEVAYLRFASVYRSFSSADDFEREIEALRAHRRVSTSR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=45.578231292517, Blast_Score=127, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17326; Mature: 17326

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCRHSDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVVAVVKRSGVTEPFSR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
GKVIRGVRRACQGRQVDDDALNLLAQQVEDTVRAAGLPEVPSHEVGLAILGPLRELDEVA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
YLRFASVYRSFSSADDFEREIEALRAHRRVSTSR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHCPFCRHSDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVVAVVKRSGVTEPFSR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
GKVIRGVRRACQGRQVDDDALNLLAQQVEDTVRAAGLPEVPSHEVGLAILGPLRELDEVA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
YLRFASVYRSFSSADDFEREIEALRAHRRVSTSR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA