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The map label for this gene is pgsA2 [H]

Identifier: 221229942

GI number: 221229942

Start: 1147815

End: 1148396

Strand: Direct

Name: pgsA2 [H]

Synonym: MLBr_00979

Alternate gene names: 221229942

Gene position: 1147815-1148396 (Clockwise)

Preceding gene: 221229940

Following gene: 221229944

Centisome position: 35.12

GC content: 57.73

Gene sequence:

>582_bases
ATGGTAGATTGCGTCCGTATTGCCAACCTCGCCAATATCCTGACTGGCTTGCGGCTGATGTTGGTCCCCGTTTTTTTGGT
TGCCTTGTTCGCTGGGAATGGCCACGAAATCGTCGGTCGGATAGCGGCTTTCGTGATCTTCACAGTTGCCTGCATTACCG
ATCGGTTAGACGGTTTGCTGGCCCGCCGCTACGGCATGGCGACTGAATTCGGTGCGTTCGTCGATCCGATCGCGGACAAG
ACCCTGATCGGGGCGGCGCTGATCGGACTTTCGATGCTTGGTGACCTGCCATGGTGGGTCACGGTGCTTATCATGACTCG
CGAGCTTGGAGTGACTTTATTGCGGTTGGCTGTTATTCATCGCGGGGTCATTCCGGCAAGTTGGGGTGGCAAACTCAAGA
CTGTGGTCCAGGCAGTAGCGATCGGTCTGTTCCTGCTGCCTTTGACGCAACTGTCAGTGCCGTTCCACGTGGGTGCAGCA
GTGGTGATGGCAGTTGCGGTCGTGCTTACGGTGGTCACGGGTGTCGACTACGTGGCTGGGACAATCAGGGCCGTCAGGGG
AGTGCACCAGACAGCCAGCTGA

Upstream 100 bases:

>100_bases
GTGAATTTTTGGTCACGGCTAACAGTATCGACATCAGGGACGCACGAGCTGGTCAACCGTTATTCTATTTGCCGTGTCGG
GGCAGCCTCCAACGGGTCCG

Downstream 100 bases:

>100_bases
TCACGGGAGCCATAGCAGGCCATCTGCGTTCATCTAGTGACTGACCGGATGAGGTGGAGCGCGATGGTGTCATTTAGTGC
GTGAAGTCATGGGCAACGTG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MVDCVRIANLANILTGLRLMLVPVFLVALFAGNGHEIVGRIAAFVIFTVACITDRLDGLLARRYGMATEFGAFVDPIADK
TLIGAALIGLSMLGDLPWWVTVLIMTRELGVTLLRLAVIHRGVIPASWGGKLKTVVQAVAIGLFLLPLTQLSVPFHVGAA
VVMAVAVVLTVVTGVDYVAGTIRAVRGVHQTAS

Sequences:

>Translated_193_residues
MVDCVRIANLANILTGLRLMLVPVFLVALFAGNGHEIVGRIAAFVIFTVACITDRLDGLLARRYGMATEFGAFVDPIADK
TLIGAALIGLSMLGDLPWWVTVLIMTRELGVTLLRLAVIHRGVIPASWGGKLKTVVQAVAIGLFLLPLTQLSVPFHVGAA
VVMAVAVVLTVVTGVDYVAGTIRAVRGVHQTAS
>Mature_193_residues
MVDCVRIANLANILTGLRLMLVPVFLVALFAGNGHEIVGRIAAFVIFTVACITDRLDGLLARRYGMATEFGAFVDPIADK
TLIGAALIGLSMLGDLPWWVTVLIMTRELGVTLLRLAVIHRGVIPASWGGKLKTVVQAVAIGLFLLPLTQLSVPFHVGAA
VVMAVAVVLTVVTGVDYVAGTIRAVRGVHQTAS

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=178, Percent_Identity=34.8314606741573, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20395; Mature: 20395

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDCVRIANLANILTGLRLMLVPVFLVALFAGNGHEIVGRIAAFVIFTVACITDRLDGLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRYGMATEFGAFVDPIADKTLIGAALIGLSMLGDLPWWVTVLIMTRELGVTLLRLAVIH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RGVIPASWGGKLKTVVQAVAIGLFLLPLTQLSVPFHVGAAVVMAVAVVLTVVTGVDYVAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TIRAVRGVHQTAS
HHHHHHHHHHCCC
>Mature Secondary Structure
MVDCVRIANLANILTGLRLMLVPVFLVALFAGNGHEIVGRIAAFVIFTVACITDRLDGLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRYGMATEFGAFVDPIADKTLIGAALIGLSMLGDLPWWVTVLIMTRELGVTLLRLAVIH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RGVIPASWGGKLKTVVQAVAIGLFLLPLTQLSVPFHVGAAVVMAVAVVLTVVTGVDYVAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TIRAVRGVHQTAS
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]