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The map label for this gene is erpA [H]

Identifier: 220918722

GI number: 220918722

Start: 4051117

End: 4051500

Strand: Direct

Name: erpA [H]

Synonym: A2cp1_3630

Alternate gene names: 220918722

Gene position: 4051117-4051500 (Clockwise)

Preceding gene: 220918721

Following gene: 220918723

Centisome position: 80.55

GC content: 66.41

Gene sequence:

>384_bases
ATGGAAGCCACCACCATCGCCGCCCCGGCCGTATCCTCCCCCGATCTGGGCATCCCGAACTTCGTCAGCCTGACCTCGAA
GGCGATCGAGATGGTGAAGGACGCCATCGCGCGCGAGGGCCTCGCGGGCTACGGCATCCGCGTCGGCGTGATGGGCGGCG
GCTGCGCCGGGTTCCAGTACTCGATGGACTTCGAGAAGGACCCGCGCGACGGCGACCTCTCGCTCGAGCAGGACGGCATC
AAGCTCTACGTCGATCCGATGAGCTCGATGTACCTCCAGGGCGTGACCATCGACTACGTCGTGGGCCTGCAGGGCGCCGG
GTTCAAGTTCAACAACCCGAACGCCCGCACCACCTGCGGCTGCGGCTCGTCCTTCTCGTACTAG

Upstream 100 bases:

>100_bases
GGGTGCGCGGTCGAACCCGCGTTGAAGCGCCCCACCCTCCCTGTTAGACTCCTTGCGCCACGTCAACGAGGGTGCGCCCC
TCGATGGAGAACTCGAAGAA

Downstream 100 bases:

>100_bases
GCATTCGCCTCGCCGGCCCGCGTGGCCGGGCGGTGCGCGCGGGCCGGAGGGGAGACCCTTCGGCCCTTCGCGTCTGGAGG
AAGCGATGCTCGTGGTCCGC

Product: iron-sulfur cluster assembly accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MEATTIAAPAVSSPDLGIPNFVSLTSKAIEMVKDAIAREGLAGYGIRVGVMGGGCAGFQYSMDFEKDPRDGDLSLEQDGI
KLYVDPMSSMYLQGVTIDYVVGLQGAGFKFNNPNARTTCGCGSSFSY

Sequences:

>Translated_127_residues
MEATTIAAPAVSSPDLGIPNFVSLTSKAIEMVKDAIAREGLAGYGIRVGVMGGGCAGFQYSMDFEKDPRDGDLSLEQDGI
KLYVDPMSSMYLQGVTIDYVVGLQGAGFKFNNPNARTTCGCGSSFSY
>Mature_127_residues
MEATTIAAPAVSSPDLGIPNFVSLTSKAIEMVKDAIAREGLAGYGIRVGVMGGGCAGFQYSMDFEKDPRDGDLSLEQDGI
KLYVDPMSSMYLQGVTIDYVVGLQGAGFKFNNPNARTTCGCGSSFSY

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=105, Percent_Identity=34.2857142857143, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI160420328, Length=82, Percent_Identity=39.0243902439024, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786351, Length=114, Percent_Identity=46.4912280701754, Blast_Score=106, Evalue=4e-25,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=38.0952380952381, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=39.622641509434, Blast_Score=78, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193209025, Length=105, Percent_Identity=37.1428571428571, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25146411, Length=105, Percent_Identity=37.1428571428571, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=35.1851851851852, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=32.3809523809524, Blast_Score=71, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24642263, Length=82, Percent_Identity=40.2439024390244, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24649697, Length=120, Percent_Identity=35.8333333333333, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13381; Mature: 13381

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATTIAAPAVSSPDLGIPNFVSLTSKAIEMVKDAIAREGLAGYGIRVGVMGGGCAGFQY
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEE
SMDFEKDPRDGDLSLEQDGIKLYVDPMSSMYLQGVTIDYVVGLQGAGFKFNNPNARTTCG
ECCCCCCCCCCCCEEECCCEEEEECCCCCCEECCCEEEEEEECCCCCEEECCCCCCEEEC
CGSSFSY
CCCCCCC
>Mature Secondary Structure
MEATTIAAPAVSSPDLGIPNFVSLTSKAIEMVKDAIAREGLAGYGIRVGVMGGGCAGFQY
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEE
SMDFEKDPRDGDLSLEQDGIKLYVDPMSSMYLQGVTIDYVVGLQGAGFKFNNPNARTTCG
ECCCCCCCCCCCCEEECCCEEEEECCCCCCEECCCEEEEEEECCCCCEEECCCCCCEEEC
CGSSFSY
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA