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The map label for this gene is alr1 [H]

Identifier: 220918668

GI number: 220918668

Start: 3995515

End: 3996702

Strand: Direct

Name: alr1 [H]

Synonym: A2cp1_3576

Alternate gene names: 220918668

Gene position: 3995515-3996702 (Clockwise)

Preceding gene: 220918665

Following gene: 220918670

Centisome position: 79.44

GC content: 76.85

Gene sequence:

>1188_bases
ATGCCCGCCATGTCCATCGTCCCCTCAACCTGGGGTGGCCGGCCCGTGTGGGCCGAGATCGACCTCGACGCCCTCGCCCA
CAACGTTCGCCTCCTCGCCGCGCGTGCCTCGCCGGCCCGCCTCTATGCCGTGGTGAAGGCGAACGCCTACGGGCACGGCG
CGGTGGCGTGCGGGCGGGCAGCGCTGGAGGCCGGCGCCCACGGCCTCGCGGTGGTGTGCGTGGACGAGGCCGAGGAGCTG
CGCCGCGCCGGGGTGGAGGCGCCGCTGCTCGTCATCGGGAACACCCCGGCCAGCGACGCGGCGCGGGTGGTCGCGCTCCG
CCTCCGGCCCGCCGTCGGCGCCATGGACCTGGTGGAGGCGCTCTCGGCCGAGGCCCGCCGCCGCGGCGCGGAGGTCCCCA
TCCACCTCGAGCTGGAGAGCGGGCTGAACCGCCACGGCCTCCCGCCCGACGCGCTGGTGGCGCTGGCCGAGCGGGCGCGC
GCGCTCCCCGGCCTCCGGGTCGAGGGCCTGTTCACCCACTTCGCCGCGGCGGAGGAGGGCGACCAGCGCTTCACGCGCGC
CCAGTTCGAGGTGCTGCGCGAGACCTCGCGCCGGCTGCCCTGGGTGCCCGAGCGCCACTGCTCCGCCTCGGCCAGCATCC
TGCTCGACCACGAGATGGCGCTCGAGGCGGTCCGGGGCGGGCTCTCGCTGTACGGCTACCGGCCCGCGCCCTGGTGCGGG
ACCGACGCCGACCTGCGCCCGGTGATGTCGCTCCGCGCCCGGGTGGCGCGCGTCTCGGACGTGGACCGCGGCGCCACCGT
CGGCTACGGCCGCACCTGGGCCGCGAACCGCCCCACCCGCGTGGCGCTGGTCATGTGCGGCTACGCCGACGGGTACCGGC
GCAGCTTCGGCAACCGGACCCAGGTGCTGGTGCACGGCCGCCGCGCGCCGGTGGTGGGCCGCGTCGCCATGGACATGTGC
ATGGTGGACGTCACCGCGGTGCCCGGCGTGGCCCCCGGCGACGTCGTGACGCTCATCGGCCGCGACGGCGACGAGCGGGT
GGACGCGGACGACCTCGCCACCATCGCCGACACGATCTCCTGGGAGATCCTGGCCGGCATCTCCGCCCGCGTGCCGCGCC
TCTACCTGCGCGGCGGGCGCGCGGTGGAGGCGAGCACGCTGGTGGATCGGGCGCCGGTCGCGATCTAG

Upstream 100 bases:

>100_bases
CTGCGGGCACGCCTGCGCTGCTCGGTCCTCGTGTGCCCAGGCTCGGCGACGCCATCGTGTGCCTCGCGACGGGCCCCTCG
CAAACGGGAGGCGCTATAAG

Downstream 100 bases:

>100_bases
CCGCGCCTCCCCGCTACACCGGCTCGAGCCAGCCGTGCGGATCCGGCGCCTCGCCGCGCTGGACGGCGTGCACGGCCGCG
CGCAGCCGCTCGCCGACCGA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MPAMSIVPSTWGGRPVWAEIDLDALAHNVRLLAARASPARLYAVVKANAYGHGAVACGRAALEAGAHGLAVVCVDEAEEL
RRAGVEAPLLVIGNTPASDAARVVALRLRPAVGAMDLVEALSAEARRRGAEVPIHLELESGLNRHGLPPDALVALAERAR
ALPGLRVEGLFTHFAAAEEGDQRFTRAQFEVLRETSRRLPWVPERHCSASASILLDHEMALEAVRGGLSLYGYRPAPWCG
TDADLRPVMSLRARVARVSDVDRGATVGYGRTWAANRPTRVALVMCGYADGYRRSFGNRTQVLVHGRRAPVVGRVAMDMC
MVDVTAVPGVAPGDVVTLIGRDGDERVDADDLATIADTISWEILAGISARVPRLYLRGGRAVEASTLVDRAPVAI

Sequences:

>Translated_395_residues
MPAMSIVPSTWGGRPVWAEIDLDALAHNVRLLAARASPARLYAVVKANAYGHGAVACGRAALEAGAHGLAVVCVDEAEEL
RRAGVEAPLLVIGNTPASDAARVVALRLRPAVGAMDLVEALSAEARRRGAEVPIHLELESGLNRHGLPPDALVALAERAR
ALPGLRVEGLFTHFAAAEEGDQRFTRAQFEVLRETSRRLPWVPERHCSASASILLDHEMALEAVRGGLSLYGYRPAPWCG
TDADLRPVMSLRARVARVSDVDRGATVGYGRTWAANRPTRVALVMCGYADGYRRSFGNRTQVLVHGRRAPVVGRVAMDMC
MVDVTAVPGVAPGDVVTLIGRDGDERVDADDLATIADTISWEILAGISARVPRLYLRGGRAVEASTLVDRAPVAI
>Mature_394_residues
PAMSIVPSTWGGRPVWAEIDLDALAHNVRLLAARASPARLYAVVKANAYGHGAVACGRAALEAGAHGLAVVCVDEAEELR
RAGVEAPLLVIGNTPASDAARVVALRLRPAVGAMDLVEALSAEARRRGAEVPIHLELESGLNRHGLPPDALVALAERARA
LPGLRVEGLFTHFAAAEEGDQRFTRAQFEVLRETSRRLPWVPERHCSASASILLDHEMALEAVRGGLSLYGYRPAPWCGT
DADLRPVMSLRARVARVSDVDRGATVGYGRTWAANRPTRVALVMCGYADGYRRSFGNRTQVLVHGRRAPVVGRVAMDMCM
VDVTAVPGVAPGDVVTLIGRDGDERVDADDLATIADTISWEILAGISARVPRLYLRGGRAVEASTLVDRAPVAI

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=362, Percent_Identity=34.5303867403315, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1790487, Length=361, Percent_Identity=34.0720221606648, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42164; Mature: 42033

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAMSIVPSTWGGRPVWAEIDLDALAHNVRLLAARASPARLYAVVKANAYGHGAVACGRA
CCCCCCCCCCCCCCEEEEECCHHHHHCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHH
ALEAGAHGLAVVCVDEAEELRRAGVEAPLLVIGNTPASDAARVVALRLRPAVGAMDLVEA
HHHCCCCCEEEEEECCHHHHHHCCCCCCEEEECCCCCHHHHEEEEEEECCCCCHHHHHHH
LSAEARRRGAEVPIHLELESGLNRHGLPPDALVALAERARALPGLRVEGLFTHFAAAEEG
HHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCH
DQRFTRAQFEVLRETSRRLPWVPERHCSASASILLDHEMALEAVRGGLSLYGYRPAPWCG
HHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEEEEHHHHHHHHHHCCCEEECCCCCCCCC
TDADLRPVMSLRARVARVSDVDRGATVGYGRTWAANRPTRVALVMCGYADGYRRSFGNRT
CCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCE
QVLVHGRRAPVVGRVAMDMCMVDVTAVPGVAPGDVVTLIGRDGDERVDADDLATIADTIS
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
WEILAGISARVPRLYLRGGRAVEASTLVDRAPVAI
HHHHHCCHHCCCEEEECCCCEEEHHHHHCCCCCCC
>Mature Secondary Structure 
PAMSIVPSTWGGRPVWAEIDLDALAHNVRLLAARASPARLYAVVKANAYGHGAVACGRA
CCCCCCCCCCCCCEEEEECCHHHHHCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHH
ALEAGAHGLAVVCVDEAEELRRAGVEAPLLVIGNTPASDAARVVALRLRPAVGAMDLVEA
HHHCCCCCEEEEEECCHHHHHHCCCCCCEEEECCCCCHHHHEEEEEEECCCCCHHHHHHH
LSAEARRRGAEVPIHLELESGLNRHGLPPDALVALAERARALPGLRVEGLFTHFAAAEEG
HHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCH
DQRFTRAQFEVLRETSRRLPWVPERHCSASASILLDHEMALEAVRGGLSLYGYRPAPWCG
HHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEEEEHHHHHHHHHHCCCEEECCCCCCCCC
TDADLRPVMSLRARVARVSDVDRGATVGYGRTWAANRPTRVALVMCGYADGYRRSFGNRT
CCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCE
QVLVHGRRAPVVGRVAMDMCMVDVTAVPGVAPGDVVTLIGRDGDERVDADDLATIADTIS
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
WEILAGISARVPRLYLRGGRAVEASTLVDRAPVAI
HHHHHCCHHCCCEEEECCCCEEEHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]