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The map label for this gene is aspC [H]

Identifier: 220918372

GI number: 220918372

Start: 3644360

End: 3645538

Strand: Direct

Name: aspC [H]

Synonym: A2cp1_3276

Alternate gene names: 220918372

Gene position: 3644360-3645538 (Clockwise)

Preceding gene: 220918371

Following gene: 220918375

Centisome position: 72.46

GC content: 77.86

Gene sequence:

>1179_bases
ATGGCCCGCCACCCCGCCCCCTCCCCCACCACCGCCACCCTCTCCGACCGCGTCTACAGCCCGACCGGCGGCCCGGTGCA
CCTGCCCCAGGGCCCGGTGTACGCGCTCAACGTGGGCGACACCTGGCGCGAGCCGCCCGCCTTCGCCCGCGCCGAGGCGC
AGCGCGTGGCCGATCACCCGGGCCTCCACGGCTACGCGCCGGTGCAGGGGGAGCCGGCGCTGCTCGACGCCATCCAGGAG
CGGCTGCAGGCGCGCGGCGGGGCGCCGGTCGCGCGCGAGGCGCTGCAGGTGGTGGTGGGCGCCACCGCGGGGCTCGCGGT
GGTGGTGGACGCGCTGCTCGACCCGGGCGACGAGGTGATCGTGCTCGCGCCCTACTGGCCGCTCATCCGCGGCATCGTGG
CGGCGCGCGGCGCCGTGCCGGTGGAGGTGCCGTTCTTCGACCGGCTCGACGCGCCGGGGTTCGACCCGGAGGCGGCGCTC
GCCGCCGCGGTGACGCCACGCACCGCGGCCATCTACGTGAACTCGCCCAACAACCCCACCGGCCGCTCGCTGCCCGACGA
GCTGGTGACCGCCCTGGCTCGCCTGGCGCGGCGCCACGCGCTGTGGGTGATCGCGGACGAGGTCTACGAGGACCTGCAGT
ACGGCACGCCGCGCCCGCCGCCGTGGACCCGCCCGGAGCTGCGCGAGCGCACCGTCGCGACCCACTCGTTCTCGAAGGCG
TACGCGCTCGCGGGCGCGCGGGTGGGCTACACGCACGGGCCCGAGGAGATCATGCGCGCGGTGCGGGCGGTGCAGACGTT
CAAGACCTACTGCGCGCCGCGTCCGTTCCAGATCGCCGCCGCCCGTGCGCTGCGCGAGGGCGACGCCTGGCTCGCGGAGA
CCCGCGCCATGTACGCGCAGGCCGGCCGCAGCGCCGCCGCCGCGCTCGGCGTGCTCGCGCCGGAGGCCGGGACGTTCCTG
TTCCTGGACGTGGCCCCGCACCTCCGGCCGGGCGAGGCGCTCGATGGCTTCCTGGCGCGCTGCCTCGAGGCGGGCGTGCT
GCTCACGCCGGGGCCGGCGACCGGCGCGGCGTACCGGACGCACGCGCGGCTCTGCTTCACCGCGGTCACGCCCGACGCGC
TCGGCGCGGCGCTGGCGCGGCTCGGGCCGCTGCTGGGGCGAACGAGCCGGCCCGACTGA

Upstream 100 bases:

>100_bases
GAGATGCGCCCCGAGTCGCGCGGCCAGCGCGGCCGCTGACGCGCACTGCCCGCCCTCCGCGGCCGGCGCGGGGGGCGGGC
GTCACCGCGCCGGCGACCCC

Downstream 100 bases:

>100_bases
GCGGCGCCGGTGGCTCCGCTCACCGCCCCGACGCGAGCCGGAGCGGCGGCGCGGAGGGCGGGTGGGGCTCCGCCCCGGCG
GCCACGCCGCGGAAGAAGCC

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MARHPAPSPTTATLSDRVYSPTGGPVHLPQGPVYALNVGDTWREPPAFARAEAQRVADHPGLHGYAPVQGEPALLDAIQE
RLQARGGAPVAREALQVVVGATAGLAVVVDALLDPGDEVIVLAPYWPLIRGIVAARGAVPVEVPFFDRLDAPGFDPEAAL
AAAVTPRTAAIYVNSPNNPTGRSLPDELVTALARLARRHALWVIADEVYEDLQYGTPRPPPWTRPELRERTVATHSFSKA
YALAGARVGYTHGPEEIMRAVRAVQTFKTYCAPRPFQIAAARALREGDAWLAETRAMYAQAGRSAAAALGVLAPEAGTFL
FLDVAPHLRPGEALDGFLARCLEAGVLLTPGPATGAAYRTHARLCFTAVTPDALGAALARLGPLLGRTSRPD

Sequences:

>Translated_392_residues
MARHPAPSPTTATLSDRVYSPTGGPVHLPQGPVYALNVGDTWREPPAFARAEAQRVADHPGLHGYAPVQGEPALLDAIQE
RLQARGGAPVAREALQVVVGATAGLAVVVDALLDPGDEVIVLAPYWPLIRGIVAARGAVPVEVPFFDRLDAPGFDPEAAL
AAAVTPRTAAIYVNSPNNPTGRSLPDELVTALARLARRHALWVIADEVYEDLQYGTPRPPPWTRPELRERTVATHSFSKA
YALAGARVGYTHGPEEIMRAVRAVQTFKTYCAPRPFQIAAARALREGDAWLAETRAMYAQAGRSAAAALGVLAPEAGTFL
FLDVAPHLRPGEALDGFLARCLEAGVLLTPGPATGAAYRTHARLCFTAVTPDALGAALARLGPLLGRTSRPD
>Mature_391_residues
ARHPAPSPTTATLSDRVYSPTGGPVHLPQGPVYALNVGDTWREPPAFARAEAQRVADHPGLHGYAPVQGEPALLDAIQER
LQARGGAPVAREALQVVVGATAGLAVVVDALLDPGDEVIVLAPYWPLIRGIVAARGAVPVEVPFFDRLDAPGFDPEAALA
AAVTPRTAAIYVNSPNNPTGRSLPDELVTALARLARRHALWVIADEVYEDLQYGTPRPPPWTRPELRERTVATHSFSKAY
ALAGARVGYTHGPEEIMRAVRAVQTFKTYCAPRPFQIAAARALREGDAWLAETRAMYAQAGRSAAAALGVLAPEAGTFLF
LDVAPHLRPGEALDGFLARCLEAGVLLTPGPATGAAYRTHARLCFTAVTPDALGAALARLGPLLGRTSRPD

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=357, Percent_Identity=24.3697478991597, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI56713254, Length=357, Percent_Identity=24.3697478991597, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI95147551, Length=315, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI169881279, Length=315, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI7705897, Length=358, Percent_Identity=24.8603351955307, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI33469970, Length=358, Percent_Identity=24.8603351955307, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI169881281, Length=238, Percent_Identity=25.2100840336134, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1786816, Length=291, Percent_Identity=31.2714776632302, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788722, Length=322, Percent_Identity=29.5031055900621, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1788627, Length=348, Percent_Identity=25.8620689655172, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790797, Length=256, Percent_Identity=27.34375, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787710, Length=275, Percent_Identity=25.8181818181818, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=394, Percent_Identity=26.9035532994924, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=394, Percent_Identity=26.9035532994924, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=304, Percent_Identity=27.3026315789474, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=24.4623655913978, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=303, Percent_Identity=27.0627062706271, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI28573069, Length=288, Percent_Identity=25.3472222222222, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646114, Length=288, Percent_Identity=25.3472222222222, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573067, Length=288, Percent_Identity=25.3472222222222, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573065, Length=288, Percent_Identity=25.3472222222222, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859735, Length=257, Percent_Identity=23.7354085603113, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41506; Mature: 41374

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHPAPSPTTATLSDRVYSPTGGPVHLPQGPVYALNVGDTWREPPAFARAEAQRVADHP
CCCCCCCCCCCEECCCCEECCCCCEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCC
GLHGYAPVQGEPALLDAIQERLQARGGAPVAREALQVVVGATAGLAVVVDALLDPGDEVI
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
VLAPYWPLIRGIVAARGAVPVEVPFFDRLDAPGFDPEAALAAAVTPRTAAIYVNSPNNPT
EECCHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCHHHHHHHEECCCEEEEEEECCCCCC
GRSLPDELVTALARLARRHALWVIADEVYEDLQYGTPRPPPWTRPELRERTVATHSFSKA
CCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
YALAGARVGYTHGPEEIMRAVRAVQTFKTYCAPRPFQIAAARALREGDAWLAETRAMYAQ
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
AGRSAAAALGVLAPEAGTFLFLDVAPHLRPGEALDGFLARCLEAGVLLTPGPATGAAYRT
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCHHHH
HARLCFTAVTPDALGAALARLGPLLGRTSRPD
HHEEEEEECCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ARHPAPSPTTATLSDRVYSPTGGPVHLPQGPVYALNVGDTWREPPAFARAEAQRVADHP
CCCCCCCCCCEECCCCEECCCCCEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCC
GLHGYAPVQGEPALLDAIQERLQARGGAPVAREALQVVVGATAGLAVVVDALLDPGDEVI
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
VLAPYWPLIRGIVAARGAVPVEVPFFDRLDAPGFDPEAALAAAVTPRTAAIYVNSPNNPT
EECCHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCHHHHHHHEECCCEEEEEEECCCCCC
GRSLPDELVTALARLARRHALWVIADEVYEDLQYGTPRPPPWTRPELRERTVATHSFSKA
CCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
YALAGARVGYTHGPEEIMRAVRAVQTFKTYCAPRPFQIAAARALREGDAWLAETRAMYAQ
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
AGRSAAAALGVLAPEAGTFLFLDVAPHLRPGEALDGFLARCLEAGVLLTPGPATGAAYRT
CCCHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCHHHH
HARLCFTAVTPDALGAALARLGPLLGRTSRPD
HHEEEEEECCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8907187; 10029535 [H]