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The map label for this gene is pntB [H]

Identifier: 220918304

GI number: 220918304

Start: 3554585

End: 3555979

Strand: Direct

Name: pntB [H]

Synonym: A2cp1_3207

Alternate gene names: 220918304

Gene position: 3554585-3555979 (Clockwise)

Preceding gene: 220918303

Following gene: 220918308

Centisome position: 70.68

GC content: 69.18

Gene sequence:

>1395_bases
GTGAGCCCGCGCACGCTGTTCATCGAGGCGGCGTACCTCGCCGCGTCGGTCCTGTTCATCCTCGGCCTCCGCAGCCTCAC
TATCCCGGACAAGGCCCGCCGCGGCATGCAGCTCGCCGCCGTCGGCATGCTGCTCGCGATCGTGGGCACGCTCGTGCACC
ACGATGTCGTCCACTACGGGTGGATCCTGGCCGGCCTGGCGCTCGGGTCGGCCATCGGCTACCCGCTCGGCGTCTACGTC
CCCATGACCGCGATGCCGCAGCGCATCGCCATCTCGCACATGTTCGGCGCGGTCGCCGCCACGCTGGTGGGCGTCGCGGA
GTACTGGCACCTGGGCAACGGCGCCCAGGTGGGCCGCGGCACGATGGCGGCGCTGGGCTTCGAGGTGCTGTTCGGCGCCC
TCACCATCACCGGCAGCTTCATGGCGTTCGGGAAGCTCCAGGAGCTGCTCCCCTCGCGGCCGGTCACCTTCCCCGGCCAG
AACGTGGTCTCGCTGCTGATGTTCGCCGCCGCGCTCGGGCTGTTCGGCTGGCTCATCCACGATCCCGGGGCGCACCCGGC
GGCGTTCTACGCCATGGTCGGGCTGGGGCTGCTGTTCGGGGTGTCGCTGGTGCTCCCCATCGGCGGCGCAGACATGCCGG
TGGTCATCTCCCTGCTCAACTCGTACGCCGGCCTGGCGTCGTCCGCGACGGGCTTCGCCATCGGCAACAACGTGCTCATC
ATCGCCGGGGCGCTCGACGGCGCCTCGGGCTTCATCCTGTCGATCATCATGAGCCGGGCGATGAACCGGTCGTTCACGAA
CGTGCTGTTCGGCGCGTTCGGCTCGGCGCCGGCGGCGTCCGCCAAGACCGCCCAGGGGCTGACGGTCCGCTCCATCACCC
CGGAGGACGCCGCCATCCAGCTCGCGTTCGCGCGGCTCGTGATCGTGGTCCCCGGCTACGGCATGGCTGTGGCGCAGGCG
CAGCACCAGGTCCGGGAGCTGGCCCAGCTCGTCGAGAAGAACGGCGGGACGGTGCTCTACGCCATCCACCCGGTGGCGGG
CCGCATGCCCGGCCACATGAACGTGCTGCTCGCCGAGGCGGACATCCCCTACGACAAGCTCAAGGAGATGGACGAGATCA
ACGACGAGTTCCAGAACGCCGACGTGGCCCTGGTGATCGGCGCGAACGACGTCGTCAACCCCGCGGCGCGGAACGATCGC
GCCTCGCCCATCTACGGGATGCCCATCCTCGACGTGGACAAGGCGAAGCAGGTCATCGTCATGAAGCGCTCGATGAACCC
GGGCTTCGCGGGCATCGAGAACGAGCTGTTCTACGCCGAGAACACCTCGATGCTGTTCGGCGACGCGAAGGCCTCGCTCG
CGAAGCTGGTGCACGAGGTGAAGCAGCAGTCCTGA

Upstream 100 bases:

>100_bases
CGGTCACCTCCGCGACCATCAACGTGGTGGGCGGCTTCATCATCACCGACCGCATGCTCAAGATGTTCAAGCGCGCCGAC
CGGGCGGGAGGCCAGAAGAA

Downstream 100 bases:

>100_bases
GCCTCGCGGCTCGCGCGCCGCCGGGCGGCGCCGGCGACGCGAGGACGGCACGGGCCCCGCGCACGACGCGCGAGGCCCGT
GCTGCCTCCGGCGCGAACGG

Product: NAD(P)(+) transhydrogenase

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSPRTLFIEAAYLAASVLFILGLRSLTIPDKARRGMQLAAVGMLLAIVGTLVHHDVVHYGWILAGLALGSAIGYPLGVYV
PMTAMPQRIAISHMFGAVAATLVGVAEYWHLGNGAQVGRGTMAALGFEVLFGALTITGSFMAFGKLQELLPSRPVTFPGQ
NVVSLLMFAAALGLFGWLIHDPGAHPAAFYAMVGLGLLFGVSLVLPIGGADMPVVISLLNSYAGLASSATGFAIGNNVLI
IAGALDGASGFILSIIMSRAMNRSFTNVLFGAFGSAPAASAKTAQGLTVRSITPEDAAIQLAFARLVIVVPGYGMAVAQA
QHQVRELAQLVEKNGGTVLYAIHPVAGRMPGHMNVLLAEADIPYDKLKEMDEINDEFQNADVALVIGANDVVNPAARNDR
ASPIYGMPILDVDKAKQVIVMKRSMNPGFAGIENELFYAENTSMLFGDAKASLAKLVHEVKQQS

Sequences:

>Translated_464_residues
MSPRTLFIEAAYLAASVLFILGLRSLTIPDKARRGMQLAAVGMLLAIVGTLVHHDVVHYGWILAGLALGSAIGYPLGVYV
PMTAMPQRIAISHMFGAVAATLVGVAEYWHLGNGAQVGRGTMAALGFEVLFGALTITGSFMAFGKLQELLPSRPVTFPGQ
NVVSLLMFAAALGLFGWLIHDPGAHPAAFYAMVGLGLLFGVSLVLPIGGADMPVVISLLNSYAGLASSATGFAIGNNVLI
IAGALDGASGFILSIIMSRAMNRSFTNVLFGAFGSAPAASAKTAQGLTVRSITPEDAAIQLAFARLVIVVPGYGMAVAQA
QHQVRELAQLVEKNGGTVLYAIHPVAGRMPGHMNVLLAEADIPYDKLKEMDEINDEFQNADVALVIGANDVVNPAARNDR
ASPIYGMPILDVDKAKQVIVMKRSMNPGFAGIENELFYAENTSMLFGDAKASLAKLVHEVKQQS
>Mature_463_residues
SPRTLFIEAAYLAASVLFILGLRSLTIPDKARRGMQLAAVGMLLAIVGTLVHHDVVHYGWILAGLALGSAIGYPLGVYVP
MTAMPQRIAISHMFGAVAATLVGVAEYWHLGNGAQVGRGTMAALGFEVLFGALTITGSFMAFGKLQELLPSRPVTFPGQN
VVSLLMFAAALGLFGWLIHDPGAHPAAFYAMVGLGLLFGVSLVLPIGGADMPVVISLLNSYAGLASSATGFAIGNNVLII
AGALDGASGFILSIIMSRAMNRSFTNVLFGAFGSAPAASAKTAQGLTVRSITPEDAAIQLAFARLVIVVPGYGMAVAQAQ
HQVRELAQLVEKNGGTVLYAIHPVAGRMPGHMNVLLAEADIPYDKLKEMDEINDEFQNADVALVIGANDVVNPAARNDRA
SPIYGMPILDVDKAKQVIVMKRSMNPGFAGIENELFYAENTSMLFGDAKASLAKLVHEVKQQS

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=463, Percent_Identity=40.6047516198704, Blast_Score=310, Evalue=3e-84,
Organism=Homo sapiens, GI122939153, Length=463, Percent_Identity=40.6047516198704, Blast_Score=310, Evalue=3e-84,
Organism=Escherichia coli, GI1787886, Length=451, Percent_Identity=46.7849223946785, Blast_Score=387, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17550456, Length=463, Percent_Identity=42.548596112311, Blast_Score=330, Evalue=8e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 48773; Mature: 48642

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRTLFIEAAYLAASVLFILGLRSLTIPDKARRGMQLAAVGMLLAIVGTLVHHDVVHYG
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
WILAGLALGSAIGYPLGVYVPMTAMPQRIAISHMFGAVAATLVGVAEYWHLGNGAQVGRG
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
TMAALGFEVLFGALTITGSFMAFGKLQELLPSRPVTFPGQNVVSLLMFAAALGLFGWLIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
DPGAHPAAFYAMVGLGLLFGVSLVLPIGGADMPVVISLLNSYAGLASSATGFAIGNNVLI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCEEE
IAGALDGASGFILSIIMSRAMNRSFTNVLFGAFGSAPAASAKTAQGLTVRSITPEDAAIQ
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHH
LAFARLVIVVPGYGMAVAQAQHQVRELAQLVEKNGGTVLYAIHPVAGRMPGHMNVLLAEA
HHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEC
DIPYDKLKEMDEINDEFQNADVALVIGANDVVNPAARNDRASPIYGMPILDVDKAKQVIV
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
MKRSMNPGFAGIENELFYAENTSMLFGDAKASLAKLVHEVKQQS
EEECCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPRTLFIEAAYLAASVLFILGLRSLTIPDKARRGMQLAAVGMLLAIVGTLVHHDVVHYG
CCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
WILAGLALGSAIGYPLGVYVPMTAMPQRIAISHMFGAVAATLVGVAEYWHLGNGAQVGRG
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
TMAALGFEVLFGALTITGSFMAFGKLQELLPSRPVTFPGQNVVSLLMFAAALGLFGWLIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
DPGAHPAAFYAMVGLGLLFGVSLVLPIGGADMPVVISLLNSYAGLASSATGFAIGNNVLI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCEEE
IAGALDGASGFILSIIMSRAMNRSFTNVLFGAFGSAPAASAKTAQGLTVRSITPEDAAIQ
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHH
LAFARLVIVVPGYGMAVAQAQHQVRELAQLVEKNGGTVLYAIHPVAGRMPGHMNVLLAEA
HHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEC
DIPYDKLKEMDEINDEFQNADVALVIGANDVVNPAARNDRASPIYGMPILDVDKAKQVIV
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
MKRSMNPGFAGIENELFYAENTSMLFGDAKASLAKLVHEVKQQS
EEECCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]