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The map label for this gene is yehU [H]

Identifier: 220918266

GI number: 220918266

Start: 3509902

End: 3511584

Strand: Direct

Name: yehU [H]

Synonym: A2cp1_3169

Alternate gene names: 220918266

Gene position: 3509902-3511584 (Clockwise)

Preceding gene: 220918261

Following gene: 220918267

Centisome position: 69.79

GC content: 73.92

Gene sequence:

>1683_bases
ATGATGGGCCGCCTGCTGCTCACGCTGTTCGAGGCGATGGCGGTCTTCTTCGTCCTGTTCCACCTCTACTCGCGCTCGCG
CGCCTTCCGGCCCGCCCGCACCGACTGGCTGCGGCCCCGCGCCAAGCTCTCGCTGCTGCTGTTCTTCACCGGCATCGCGA
TCCTCGGCACCTACCTCGGCCTCCCGCTCGCGGGCGGCGCCATCGCCAACACCCGCGCCGTGGGCGCGGTCCTGGGTGGC
ATGCTGGGCGGGCCGGCGGTGGGCGTGGCGGTGGGCCTGCTCTCGGGCGCGCACCGCCTCACCCTGGGCGGCTTCACCGC
CGGCGCTGGGGCCATCGCCACCACGCTGGAGGGGCTGATGGGCGGGCTGGTGCACCGGCGGCTCGCCTCGGCCGCGCCGG
ACCGGCTCATCTCCTGGAAGCTCGCCTTCGCGGTGACCGCCGCCGGCGAGGCGCTCCACATGGGCCTGCTGCTCGCCGTG
TCCCGGCCGTTCCACGAGTCGGTCCGCGTGGTGGAGGGCATCGGCGTGCCCATGATCCTGGCGAACTCGGTGGGCGCGGC
GCTGTTCATGACGCTGCTGCGCGACCGCCACGAGCGCTACGATCGCCTGGCCGCCGCCACCTCCGCGAAGGCGCTCCGGA
TCGCCGAGCGGACGCTGGGCCCCCTCGCGCGCGGCTTCGATCGCTCGGTCGCCGGCGAGCTGGCCTCCATCATCCAGGAG
GAGACCGGGGTGGGCGCGGTGGCCATCACCGACACCGAGACGGTGCTCGCGTTCGTGGGGCGCGGGTCCGACCACCACCG
GCCCGGCCTGCCCATCGCCTCGCCGCTGACCCGCGGCGCCATCGAGCGGCACGAGGTGGTGTTCGCGGACGGCGAGCACG
AGCACTACCGCTGCGCGGTCTCGGCGGCCTGCCCGCTCGACTCGGCGGTGGTCATCCCGCTGGTGGTGGACGGCGCGGCC
ATCGGGACGGTGCAGCTCCTCGAGACCGCGCGCACCCGGTTCCGGCGGCTGAACCGGTCGCTGGGCGAGGGCATCGCCGA
CCTGCTCTCCGACCAGCTCCTGCGGGCCCGCTTCCACGAGCAGAAGAGCCTGCTCGTCCTCACGGAGCTGAAGCTCCTGC
AGGCGCAGGTGGACCCGCACTTCCTGTTCAACGCGCTCAACACCGTGCACGCCGTCACCCGCACCGACCCGGAGCGTGCC
CGCGAGCTGCTCGGCCACCTCTCCGCGCTGTTCCGCAAGAACCTGAAGCGCTCCGCCCCGCTCTCCACGCTGGAGGAGGA
GCTGGAGCACGCCGGCGCCTACCTGGAGATCGAGAAGGCCCGCTTCGGCGACCGCCTGGCGGTCCTCACCGAGGTGGACC
CGGCGCTGCTGCGGCTGCGGCTGCCCACGTTCACGCTGCAGCCGCTCATCGAGAACGCGGTGAAGCACGGCCTCGGCGCG
ACGCTCGGGCAGGCCACCGCCCGCATCCGCGCCTACCGCCAGGGCGCCACGGCGGTGATCGAGATCGAGGACGACGCCGG
CGCCTACGCGCCGCGGGCCGGCGCCGACGGGATGGGCATGAGCCTGGTGGACCGGCGCATCAAGAACCTGCTGGGCGCGG
AGTGGGGGGTCACCGTCTCCTGCACGCCGAGCGCGCTGACGCGCGTGTCGGTGCGGGTGCCGTTCGAGGAGCGTCCCGCG
TGA

Upstream 100 bases:

>100_bases
CGGCGGACCGATCCCGGGCCCTCGTTTGCGCCCCCCGAGCGCCGGGCGCTATCGTCGCGCTCCCGCCGCCCGCCGCGGCG
GCCCGGAGGACCGGAACGCG

Downstream 100 bases:

>100_bases
TGCGCGCCGTCATCGTGGACGACGAGCCCAACGCCCGGGCCGAGCTGCGCGCGCTGCTCCAGGCCACCGGCGAGGTGGAG
ATCGCGGCCGACTGCGGCAA

Product: signal transduction histidine kinase LytS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MMGRLLLTLFEAMAVFFVLFHLYSRSRAFRPARTDWLRPRAKLSLLLFFTGIAILGTYLGLPLAGGAIANTRAVGAVLGG
MLGGPAVGVAVGLLSGAHRLTLGGFTAGAGAIATTLEGLMGGLVHRRLASAAPDRLISWKLAFAVTAAGEALHMGLLLAV
SRPFHESVRVVEGIGVPMILANSVGAALFMTLLRDRHERYDRLAAATSAKALRIAERTLGPLARGFDRSVAGELASIIQE
ETGVGAVAITDTETVLAFVGRGSDHHRPGLPIASPLTRGAIERHEVVFADGEHEHYRCAVSAACPLDSAVVIPLVVDGAA
IGTVQLLETARTRFRRLNRSLGEGIADLLSDQLLRARFHEQKSLLVLTELKLLQAQVDPHFLFNALNTVHAVTRTDPERA
RELLGHLSALFRKNLKRSAPLSTLEEELEHAGAYLEIEKARFGDRLAVLTEVDPALLRLRLPTFTLQPLIENAVKHGLGA
TLGQATARIRAYRQGATAVIEIEDDAGAYAPRAGADGMGMSLVDRRIKNLLGAEWGVTVSCTPSALTRVSVRVPFEERPA

Sequences:

>Translated_560_residues
MMGRLLLTLFEAMAVFFVLFHLYSRSRAFRPARTDWLRPRAKLSLLLFFTGIAILGTYLGLPLAGGAIANTRAVGAVLGG
MLGGPAVGVAVGLLSGAHRLTLGGFTAGAGAIATTLEGLMGGLVHRRLASAAPDRLISWKLAFAVTAAGEALHMGLLLAV
SRPFHESVRVVEGIGVPMILANSVGAALFMTLLRDRHERYDRLAAATSAKALRIAERTLGPLARGFDRSVAGELASIIQE
ETGVGAVAITDTETVLAFVGRGSDHHRPGLPIASPLTRGAIERHEVVFADGEHEHYRCAVSAACPLDSAVVIPLVVDGAA
IGTVQLLETARTRFRRLNRSLGEGIADLLSDQLLRARFHEQKSLLVLTELKLLQAQVDPHFLFNALNTVHAVTRTDPERA
RELLGHLSALFRKNLKRSAPLSTLEEELEHAGAYLEIEKARFGDRLAVLTEVDPALLRLRLPTFTLQPLIENAVKHGLGA
TLGQATARIRAYRQGATAVIEIEDDAGAYAPRAGADGMGMSLVDRRIKNLLGAEWGVTVSCTPSALTRVSVRVPFEERPA
>Mature_560_residues
MMGRLLLTLFEAMAVFFVLFHLYSRSRAFRPARTDWLRPRAKLSLLLFFTGIAILGTYLGLPLAGGAIANTRAVGAVLGG
MLGGPAVGVAVGLLSGAHRLTLGGFTAGAGAIATTLEGLMGGLVHRRLASAAPDRLISWKLAFAVTAAGEALHMGLLLAV
SRPFHESVRVVEGIGVPMILANSVGAALFMTLLRDRHERYDRLAAATSAKALRIAERTLGPLARGFDRSVAGELASIIQE
ETGVGAVAITDTETVLAFVGRGSDHHRPGLPIASPLTRGAIERHEVVFADGEHEHYRCAVSAACPLDSAVVIPLVVDGAA
IGTVQLLETARTRFRRLNRSLGEGIADLLSDQLLRARFHEQKSLLVLTELKLLQAQVDPHFLFNALNTVHAVTRTDPERA
RELLGHLSALFRKNLKRSAPLSTLEEELEHAGAYLEIEKARFGDRLAVLTEVDPALLRLRLPTFTLQPLIENAVKHGLGA
TLGQATARIRAYRQGATAVIEIEDDAGAYAPRAGADGMGMSLVDRRIKNLLGAEWGVTVSCTPSALTRVSVRVPFEERPA

Specific function: Unknown

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788446, Length=556, Percent_Identity=45.5035971223022, Blast_Score=463, Evalue=1e-131,
Organism=Escherichia coli, GI1788723, Length=544, Percent_Identity=29.0441176470588, Blast_Score=229, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: NA

Molecular weight: Translated: 59977; Mature: 59977

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGRLLLTLFEAMAVFFVLFHLYSRSRAFRPARTDWLRPRAKLSLLLFFTGIAILGTYLG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHC
LPLAGGAIANTRAVGAVLGGMLGGPAVGVAVGLLSGAHRLTLGGFTAGAGAIATTLEGLM
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
GGLVHRRLASAAPDRLISWKLAFAVTAAGEALHMGLLLAVSRPFHESVRVVEGIGVPMIL
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHH
ANSVGAALFMTLLRDRHERYDRLAAATSAKALRIAERTLGPLARGFDRSVAGELASIIQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ETGVGAVAITDTETVLAFVGRGSDHHRPGLPIASPLTRGAIERHEVVFADGEHEHYRCAV
HCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHCEEEEECCCCCCEEEEE
SAACPLDSAVVIPLVVDGAAIGTVQLLETARTRFRRLNRSLGEGIADLLSDQLLRARFHE
EECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKSLLVLTELKLLQAQVDPHFLFNALNTVHAVTRTDPERARELLGHLSALFRKNLKRSAP
CCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
LSTLEEELEHAGAYLEIEKARFGDRLAVLTEVDPALLRLRLPTFTLQPLIENAVKHGLGA
HHHHHHHHHHCCCEEEEHHHCCCCCEEEEECCCHHHHEEECCCHHHHHHHHHHHHHCCCH
TLGQATARIRAYRQGATAVIEIEDDAGAYAPRAGADGMGMSLVDRRIKNLLGAEWGVTVS
HHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
CTPSALTRVSVRVPFEERPA
ECHHHHCEEEEECCCCCCCC
>Mature Secondary Structure
MMGRLLLTLFEAMAVFFVLFHLYSRSRAFRPARTDWLRPRAKLSLLLFFTGIAILGTYLG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHC
LPLAGGAIANTRAVGAVLGGMLGGPAVGVAVGLLSGAHRLTLGGFTAGAGAIATTLEGLM
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
GGLVHRRLASAAPDRLISWKLAFAVTAAGEALHMGLLLAVSRPFHESVRVVEGIGVPMIL
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHH
ANSVGAALFMTLLRDRHERYDRLAAATSAKALRIAERTLGPLARGFDRSVAGELASIIQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ETGVGAVAITDTETVLAFVGRGSDHHRPGLPIASPLTRGAIERHEVVFADGEHEHYRCAV
HCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHCEEEEECCCCCCEEEEE
SAACPLDSAVVIPLVVDGAAIGTVQLLETARTRFRRLNRSLGEGIADLLSDQLLRARFHE
EECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKSLLVLTELKLLQAQVDPHFLFNALNTVHAVTRTDPERARELLGHLSALFRKNLKRSAP
CCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
LSTLEEELEHAGAYLEIEKARFGDRLAVLTEVDPALLRLRLPTFTLQPLIENAVKHGLGA
HHHHHHHHHHCCCEEEEHHHCCCCCEEEEECCCHHHHEEECCCHHHHHHHHHHHHHCCCH
TLGQATARIRAYRQGATAVIEIEDDAGAYAPRAGADGMGMSLVDRRIKNLLGAEWGVTVS
HHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
CTPSALTRVSVRVPFEERPA
ECHHHHCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]