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The map label for this gene is gluP [H]

Identifier: 220918079

GI number: 220918079

Start: 3302815

End: 3303897

Strand: Direct

Name: gluP [H]

Synonym: A2cp1_2980

Alternate gene names: 220918079

Gene position: 3302815-3303897 (Clockwise)

Preceding gene: 220918077

Following gene: 220918080

Centisome position: 65.67

GC content: 78.86

Gene sequence:

>1083_bases
ATGCACACGGACGCCCCACGCCCTCGGGACGGGCTCGCGGCCCGGCTGCGCGCCGCGCCCGGCACGGTGGCCCTCGCCGC
CGCGGATCTCGCCGTCTTCGGGTGGGTGGCGGCCCATGGCTCCACGACCGACCCCGCGCTCCTCGCCCGAATGGGCGCGC
TCGACCATGCGCGCGTGTGGGATGGCGAGCCCTGGCGCCTCCTCACCGCCGCGTTCCTGCACGTCGGCCCCGTTCACCTG
GTGTGGAACCTGGCGTTCGGGGTGCCGCTCTGCGCGCTGGTGGAGCGGGCCATCGGCACCCGCCGCTTCCTCGCCGTGTA
CGTGGCGAGCGCGCTGGGCGGCTCCGCCGCCTCGATGCTGGCCGCGATGCCGATGTCGGCGGGCGCCTCGGGGGCGCTGT
TCGGCGTCGCCGGCGCCATGCTGGCGCTGTACCGGCGCGCGGTGGGGTCCTGGCGCGCGTTCCTCGCCTCGCGCGACATC
ATCCTGAACGGGATCCTGCTCGTCGGGTTCGCGCTGGCGGGGCTGTTCCTGCCCATCGACGGGTGGGCGCACGCCGGCGG
GCTCGCCACCGGCGCTTGGCTCGGCTGGATCGCCTCGCGCCCGGCGCCCCGTCGAGCCCGGGCCTGGCTCCCGCCCGCCG
CCGCGCTCGGCCTCGCGATCGCGCTGGCGCTGCGACCCGATCCCCGGTGGGCGGCGAACCGCAGCGAGCTGGAGGCGATG
CACGCCGCGCTGCGCGACGGCGACCGCACGCGGGCGCGCGCGGTGCTGGACGCCGCGCGCGCCCGCGGCAACGACGCCGC
CGGGCTGCCGTACTACGAGGGGCTGCTGCTCGCGCAGGAGGGGGATCTCGACGGTGCGCTGGAGCGGCTGCGGCCGCTCG
CGTCCGCCGCGCAGGGTCCGGCGGGCGAGGAGGCGCGGAGGGCGCTCGCCGCGGTGGCGAAGCGCCTGGGCGTGCTGCTC
GTGGTCGGCGACGGGCGCCCGCCCGATCCGGCGCGCGGCCGGGCGCTGCTCGACGAGGCCTGTGGCGCCGGGGACGCGGA
CGCCTGCCGGCTCGCCGCCGACGCCGCCGCGCTGGATCGGTGA

Upstream 100 bases:

>100_bases
GCGTGGGTTGACGATGGTGTCGGCGTCGCTCATCGATCCGGACGGTATCCGAACGCGAGCGGCCGCACGAACCCGGGGTC
ACGGTACACTCCCGCGCCGC

Downstream 100 bases:

>100_bases
ACCCCCGGCGCGGAACGGACCATCGGTCCGGCTCCCGCGTTCACCTCTCGTGCATCCTCATTGGGGCGGACCGCCGCGCC
CGCGTCGGTTCCGGACCGCG

Product: Rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MHTDAPRPRDGLAARLRAAPGTVALAAADLAVFGWVAAHGSTTDPALLARMGALDHARVWDGEPWRLLTAAFLHVGPVHL
VWNLAFGVPLCALVERAIGTRRFLAVYVASALGGSAASMLAAMPMSAGASGALFGVAGAMLALYRRAVGSWRAFLASRDI
ILNGILLVGFALAGLFLPIDGWAHAGGLATGAWLGWIASRPAPRRARAWLPPAAALGLAIALALRPDPRWAANRSELEAM
HAALRDGDRTRARAVLDAARARGNDAAGLPYYEGLLLAQEGDLDGALERLRPLASAAQGPAGEEARRALAAVAKRLGVLL
VVGDGRPPDPARGRALLDEACGAGDADACRLAADAAALDR

Sequences:

>Translated_360_residues
MHTDAPRPRDGLAARLRAAPGTVALAAADLAVFGWVAAHGSTTDPALLARMGALDHARVWDGEPWRLLTAAFLHVGPVHL
VWNLAFGVPLCALVERAIGTRRFLAVYVASALGGSAASMLAAMPMSAGASGALFGVAGAMLALYRRAVGSWRAFLASRDI
ILNGILLVGFALAGLFLPIDGWAHAGGLATGAWLGWIASRPAPRRARAWLPPAAALGLAIALALRPDPRWAANRSELEAM
HAALRDGDRTRARAVLDAARARGNDAAGLPYYEGLLLAQEGDLDGALERLRPLASAAQGPAGEEARRALAAVAKRLGVLL
VVGDGRPPDPARGRALLDEACGAGDADACRLAADAAALDR
>Mature_360_residues
MHTDAPRPRDGLAARLRAAPGTVALAAADLAVFGWVAAHGSTTDPALLARMGALDHARVWDGEPWRLLTAAFLHVGPVHL
VWNLAFGVPLCALVERAIGTRRFLAVYVASALGGSAASMLAAMPMSAGASGALFGVAGAMLALYRRAVGSWRAFLASRDI
ILNGILLVGFALAGLFLPIDGWAHAGGLATGAWLGWIASRPAPRRARAWLPPAAALGLAIALALRPDPRWAANRSELEAM
HAALRDGDRTRARAVLDAARARGNDAAGLPYYEGLLLAQEGDLDGALERLRPLASAAQGPAGEEARRALAAVAKRLGVLL
VVGDGRPPDPARGRALLDEACGAGDADACRLAADAAALDR

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 37229; Mature: 37229

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTDAPRPRDGLAARLRAAPGTVALAAADLAVFGWVAAHGSTTDPALLARMGALDHARVW
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC
DGEPWRLLTAAFLHVGPVHLVWNLAFGVPLCALVERAIGTRRFLAVYVASALGGSAASML
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AAMPMSAGASGALFGVAGAMLALYRRAVGSWRAFLASRDIILNGILLVGFALAGLFLPID
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GWAHAGGLATGAWLGWIASRPAPRRARAWLPPAAALGLAIALALRPDPRWAANRSELEAM
CCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
HAALRDGDRTRARAVLDAARARGNDAAGLPYYEGLLLAQEGDLDGALERLRPLASAAQGP
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEECCCHHHHHHHHHHHHHHHCCC
AGEEARRALAAVAKRLGVLLVVGDGRPPDPARGRALLDEACGAGDADACRLAADAAALDR
CCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHTDAPRPRDGLAARLRAAPGTVALAAADLAVFGWVAAHGSTTDPALLARMGALDHARVW
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC
DGEPWRLLTAAFLHVGPVHLVWNLAFGVPLCALVERAIGTRRFLAVYVASALGGSAASML
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AAMPMSAGASGALFGVAGAMLALYRRAVGSWRAFLASRDIILNGILLVGFALAGLFLPID
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GWAHAGGLATGAWLGWIASRPAPRRARAWLPPAAALGLAIALALRPDPRWAANRSELEAM
CCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
HAALRDGDRTRARAVLDAARARGNDAAGLPYYEGLLLAQEGDLDGALERLRPLASAAQGP
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHCEEEEECCCHHHHHHHHHHHHHHHCCC
AGEEARRALAAVAKRLGVLLVVGDGRPPDPARGRALLDEACGAGDADACRLAADAAALDR
CCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]